Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
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Sommaire du n° 542 du 28 octobre 2022
Qualité de vie, soins de support (3)
A partir d'une revue de la littérature (11 études), cette étude identifie les caractéristiques des interventions d'aide à la décision concernant la préservation de la fertilité des patients atteints d'un cancer
Supporting decision-making regarding fertility preservation in patients with cancer: An integrative review
A partir d'une revue de la littérature (11 études), cette étude identifie les caractéristiques des interventions d'aide à la décision concernant la préservation de la fertilité des patients atteints d'un cancer
Supporting decision-making regarding fertility preservation in patients with cancer: An integrative review
Han, Jeehee ; Park, Sangwoo ; Kim, Sung Hae
Introduction : Recent reproductive technology for cancer patients has provided multiple options to preserve their fertility. Preserving fertility can increase quality of life of cancer patients. However, medical service providers and patients face difficulties in the decision-making process for the fertility preserving treatment because studies focusing on the concept of decision-making and various intervention materials are lack. This review aims to identify the attributes of interventions of [...]
Menée en France à l'Institut Gustave Roussy à partir de données portant sur 187 patients atteints d'un cancer et inclus dans un essai de phase I, cette étude prospective analyse leur qualité de vie, leur sexualité et leurs besoins en soins de support
Evaluation of supportive care needs, sexuality and quality of life in phase 1 trials: a prospective monocentric study
Menée en France à l'Institut Gustave Roussy à partir de données portant sur 187 patients atteints d'un cancer et inclus dans un essai de phase I, cette étude prospective analyse leur qualité de vie, leur sexualité et leurs besoins en soins de support
Evaluation of supportive care needs, sexuality and quality of life in phase 1 trials: a prospective monocentric study
Hilmi, Marc ; Naoun, Natacha ; Boilève, Alice ; Geraud, Arthur ; Bayle, Arnaud ; Pages, Arnaud ; Aupomerol, Marion ; Rouanne, Matthieu ; Madec, François-Xavier ; Pommeret, Fanny ; Massard, Christophe ; Baldini, Capucine ; Scotté, Florian ; Champiat, Stéphane
Purpose : Patients enrolled in oncology phase 1 trials (ph1) usually have advanced heavily pre-treated cancers with few therapeutic options. Quality of life (QoL) is one of the key cancer-treatment outcome measures, especially in ph1, and sexuality is an important part of Qol but rarely explored. This prospective study aims to assess supportive care needs, QoL and sexuality in ph1. Methods : Between September 2020 and June 2021, we prospectively recruited patients enrolled in ph1 at Gustave [...]
A partir d'une revue systématique de la littérature publiée entre 2005 et 2022 (21 études incluant 1 377 aidants), cette étude analyse l'intérêt, pour les aidants de patients adultes atteints d'un gliome de haut grade, de différentes stratégies de soins de support
Benefits of supportive strategies for carers of people with high-grade glioma: a systematic review
A partir d'une revue systématique de la littérature publiée entre 2005 et 2022 (21 études incluant 1 377 aidants), cette étude analyse l'intérêt, pour les aidants de patients adultes atteints d'un gliome de haut grade, de différentes stratégies de soins de support
Benefits of supportive strategies for carers of people with high-grade glioma: a systematic review
Jones, Diana ; Pinkham, Mark B. ; Wallen, Matthew P. ; Hart, Nicolas H. ; Joseph, Ria ; Strodl, Esben ; Ownsworth, Tamara ; Beesley, Vanessa ; Crichton, Megan ; Chan, Raymond J.
Purpose : To systematically review and examine current evidence for the carer-reported benefits of supportive care strategies for carers of adults with high-grade glioma (HGG). Methods : Four databases (CINAHL, EMBASE, PubMed, PsycINFO) were searched for articles published between January 2005 and April 2022 that assessed strategies for addressing the supportive care needs of carers of adults with HGG (WHO grade 3–4). Study selection and critical appraisal were conducted independently by three [...]
Observation (2)
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Temporal changes of the incidence of childhood B-cell precursor acute lymphoblastic leukaemia in Germany during the COVID-19 pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Temporal changes of the incidence of childhood B-cell precursor acute lymphoblastic leukaemia in Germany during the COVID-19 pandemic
Borkhardt, Arndt ; Schüz, Joachim ; Trübenbach, Claudia ; Wellbrock, Maike ; Spix, Claudia ; Erdmann, Friederike
Acute lymphoblastic leukaemia is the most common malignancy in children, but despite a growing body of research, its aetiology remains incompletely understood and there is a lack of primary preventive measures. The complex interplay between genetic predispositions—be it inherited or somatically acquired during fetal development—and postnatal environmental triggers has become a focus of research into childhood acute lymphoblastic leukaemia (ALL). There is evidence that specific patterns of [...]
Evaluating the Short-term Environmental and Clinical Effects of a Radiation Oncology Department's Response to the COVID-19 Pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Evaluating the Short-term Environmental and Clinical Effects of a Radiation Oncology Department's Response to the COVID-19 Pandemic
Cheung, Ronald ; Ito, Emma ; Lopez, Marianela ; Rubinstein, Ed ; Keller, Harald ; Cheung, Fred ; Liu, Zhihui Amy ; Liu, Fei-Fei ; Wong, Philip
Purpose: During the COVID-19 pandemic, many radiation oncology departments worldwide adopted the use of shorter and more intense hypofractionated regimens. Hospital foot traffic was reduced through virtual care. This study's primary objective was to assess the collective environmental effect of these strategic changes by identifying sources of carbon dioxide equivalents (CO2e). The rate of radiation-related adverse events from the increased use of hypofractionated treatments was assessed. [...]
Immunogenicity of COVID-19 mRNA vaccines in patients with acute myeloid leukemia and myelodysplastic syndrome
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Immunogenicity of COVID-19 mRNA vaccines in patients with acute myeloid leukemia and myelodysplastic syndrome
Helfgott, David C. ; Racine-Brzostek, Sabrina ; Short, Kelsey J. ; Zhao, Zhen ; Christos, Paul ; Nino, Itzel ; Niu, Tina ; Contreras, Jorge ; Ritchie, Ellen K. ; Desai, Pinkal ; Samuel, Michael ; Roboz, Gail J.
Immunocompromised patients are susceptible to complications from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The mRNA vaccines BNT162b2 and mRNA-1273 are effective in immunocompetent adults, but have diminished activity in immunocompromised patients. We measured anti-spike SARS-CoV-2 antibody (anti-S) response, avidity, and surrogate neutralizing antibody activity in COVID-19 vaccinated patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Anti-S was [...]
Gender, bladder cancer healthcare and burden of COVID-19
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Gender, bladder cancer healthcare and burden of COVID-19
khansary, Shahede ; Tavilani, Heidar ; Ghasemi, Hadi
Bladder cancer as one of the main comorbid diseases might be more susceptible to develop COVID-19 infection with a higher mortality risk during the COVID-19 pandemic. The European Association of Urology (EAU) recommended a comprehensive panel for bladder cancer diagnosis and treatment during this global health problem. The urgent need for treatments of COVID-19 during the pandemic has persuaded researchers to evaluate the different medications, which may lead to drug shortages. Therefore, in [...]
B-cell malignancies treated with targeted drugs and SARS-CoV-2 infection: A European Hematology Association Survey (EPICOVIDEHA)
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
B-cell malignancies treated with targeted drugs and SARS-CoV-2 infection: A European Hematology Association Survey (EPICOVIDEHA)
Maria Stefania Infante, ; Jon Salmanton-García, ; Ana Fernández-Cruz, ; et al.
Patients with lymphoproliferative diseases (LPD) are vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Here, we describe and analyze the outcome of 366 adult patients with chronic lymphocytic leukemia (CLL) or non-Hodgkin Lymphoma (NHL) treated with targeted drugs and laboratory-confirmed COVID-19 diagnosed between February 2020 and January 2022. Median follow-up was 70.5 days (IQR 0-609). Most used targeted drugs were Bruton-kinase inhibitors (BKIs) (N= 201, [...]
SARS-CoV-2 infection in patients with chronic lymphocytic leukemia: The Italian Hematology Alliance on COVID-19 cohort
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
SARS-CoV-2 infection in patients with chronic lymphocytic leukemia: The Italian Hematology Alliance on COVID-19 cohort
Merli, Michele ; Ferrarini, Isacco ; Merli, Francesco ; Busca, Alessandro ; Mina, Roberto ; Falini, Brunangelo ; Bruna, Riccardo ; Cairoli, Roberto ; Marchetti, Monia ; Romano, Alessandra ; Cavo, Michele ; Arcaini, Luca ; Trentin, Livio ; Cattaneo, Chiara ; Derenzini, Enrico ; Fracchiolla, Nicola Stefano ; Marchesi, Francesco ; Scattolin, Annamaria ; Billio, Atto ; Bocchia, Monica ; Massaia, Massimo ; Gambacorti-Passerini, Carlo ; Mauro, Francesca Romana ; Gentile, Massimo ; Mohamed, Sara ; Della Porta, Matteo Giovanni ; Coviello, Elisa ; Cilloni, Daniela ; Visani, Giuseppe ; Federici, Augusto Bramante ; Tisi, Maria Chiara ; Cudillo, Laura ; Galimberti, Sara ; Gherlinzoni, Filippo ; Pagano, Livio ; Guidetti, Anna ; Bertù, Lorenza ; Corradini, Paolo ; Passamonti, Francesco ; Visco, Carlo
COVID-19, the disease caused by SARS-CoV-2, is still afflicting thousands of people across the globe. Few studies on COVID-19 in chronic lymphocytic leukemia (CLL) are available. Here, we analyzed data from the CLL cohort of the Italian Hematology Alliance on COVID-19 (NCT04352556), which included 256 CLL patients enrolled between February 25, 2020 and February 1, 2021. Median age was 70 years (range 38-94) with male preponderance (60.1%). Approximately half of patients (n=127) had received at [...]
Health influence of SARS-CoV-2 (COVID-19) on cancer: a review
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Health influence of SARS-CoV-2 (COVID-19) on cancer: a review
Rachel Parise ; Yiran E. Li ; Rishi M. Nadar ; Sindhu Ramesh ; Jun Ren ; Manoj Yogish Govindarajulu ; Timothy Moore ; Muralikrishnan Dhanasekaran
The novel coronavirus, namely, SARS-CoV-2 (COVID-19), broke out two years ago and has caused major global health issues. Adequate treatment options are still lacking for the management of COVID-19 viral infections. Many patients afflicted with COVID-19 may range from asymptomatic to severe symptomatic, triggering poor clinical outcomes, morbidity, and mortality. Cancer is one of the leading causes of death worldwide. It is pertinent to re-examine cancer prevalence during the COVID-19 pandemic [...]
Association between social connectedness and stress or anxiety among older cancer survivors during the 2020–2021 winter surge of the COVID-19 pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Association between social connectedness and stress or anxiety among older cancer survivors during the 2020–2021 winter surge of the COVID-19 pandemic
Poghosyan, Hermine ; Margaryan, Yeva ; Jeon, Sangchoon ; Edelman, E. Jennifer ; Yu, James B.
Introduction : Our goal was to estimate a relative decreased rate of social connectedness to family and friends, increased rate of stress or anxiety during the 2020–2021 winter surge of the COVID-19 pandemic, and investigate the association between social connectedness and stress or anxiety among a nationally representative sample of older adults with cancer history. Materials and Methods : We used population-based, nationally representative cross-sectional data from the Medicare Current [...]
Management of acute promyelocytic leukemia in the setting of acute COVID-19 infection
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Management of acute promyelocytic leukemia in the setting of acute COVID-19 infection
Shim, Kevin G. ; Crain, Mallory ; Augustin, Kristan ; Oetjen, Karolyn A.
Acute promyelocytic leukemia (APL) often presents with significant coagulopathy which may result in both hemorrhagic and thrombotic complications. The emergence of the COVID-19 pandemic has complicated the initial treatment and diagnosis of APL owing to the viral infection's own associated coagulopathy. Here we report two cases of APL newly diagnosed in the setting of COVID-19 infection and considerations in their management. Included is a discussion of strategies for the dosing of arsenic [...]
Menée dans 11 pays d'Afrique sub-saharienne à partir de données de 12 registres des cancers portant sur un total de 5 423 patientes atteintes d'un cancer de l'ovaire, cette étude analyse l'évolution de l'incidence de la maladie sur différentes périodes
Trends in the Incidence of Ovarian Cancer in sub-Saharan Africa
Menée dans 11 pays d'Afrique sub-saharienne à partir de données de 12 registres des cancers portant sur un total de 5 423 patientes atteintes d'un cancer de l'ovaire, cette étude analyse l'évolution de l'incidence de la maladie sur différentes périodes
Trends in the Incidence of Ovarian Cancer in sub-Saharan Africa
Gizaw, Muluken ; Parkin, Donald Maxwell ; Stöter, Ole ; Korir, Anne ; Kamate, Bakarou ; Liu, Biying ; Bojang, Lamin ; N'Da, Guy ; Manraj, Shyam S. ; Bukirwa, Phiona ; Chokunonga, Eric ; Chingonzoh, Tatenda ; Peko, Jean-Félix ; Finesse, Anne ; Somdyala, Nontuthuzelo ; Ladipo, Akinade ; Kantelhardt, Eva Johanna
Ovarian cancer (OC) is one of the commonest cancers of women in sub-Saharan Africa (SSA), although to date no data have been available on time trends in incidence to better understand the disease pattern in the region. We estimate time trends by histological subtype from 12 population-based cancer registries in 11 countries: Kenya (Nairobi), Mauritius, Seychelles, Uganda (Kampala), Congo (Brazzaville), Zimbabwe (Bulawayo and Harare), Cote d'Ivoire (Abidjan), The Gambia, Mali (Bamako), Nigeria [...]
Approches psycho-sociales (2)
Menée en Chine à partir de données portant sur 588 patients atteints d'un cancer, cette étude de cohorte transversale analyse les facteurs associés au risque de pensées suicidaires
Incidence and risk factors for suicidal ideation in a sample of Chinese patients with mixed cancer types
Menée en Chine à partir de données portant sur 588 patients atteints d'un cancer, cette étude de cohorte transversale analyse les facteurs associés au risque de pensées suicidaires
Incidence and risk factors for suicidal ideation in a sample of Chinese patients with mixed cancer types
Lai, Qianlin ; Huang, Hong ; Zhu, Yinting ; Shu, Siwei ; Chen, Yaner ; Luo, Yuanyuan ; Zhang, Lili ; Yang, Zhihui
Purpose : Suicidal ideation (SI) is often overlooked as a risk factor for people with cancer. Because it is often a precursor for suicidal behavior, it is critical to identify and address SI in a timely manner. This study investigated SI incidence and risk factors in a cohort of Chinese patients with mixed cancer types. Method : Data from this cross-sectional study were collected from 588 patients receiving medical therapy for tumors at Nanfang Hospital and the Integrated Hospital of [...]
Menée aux Etats-Unis par enquête auprès de 154 patientes ayant survécu à un cancer gynécologique, cette étude identifie les facteurs psychosociaux associés à la peur de la récidive de la maladie
Psychosocial Predictors of Fear of Cancer Recurrence in a Cohort of Gynecologic Cancer Survivors
Menée aux Etats-Unis par enquête auprès de 154 patientes ayant survécu à un cancer gynécologique, cette étude identifie les facteurs psychosociaux associés à la peur de la récidive de la maladie
Psychosocial Predictors of Fear of Cancer Recurrence in a Cohort of Gynecologic Cancer Survivors
Mell, Carlie A. ; Jewett, Patricia I. ; Teoh, Deanna ; Vogel, Rachel I. ; Everson-Rose, Susan A.
Objective : To describe fear of cancer recurrence in a cohort of women with gynecologic cancers and to identify psychosocial predictors of elevated fear of recurrence. Methods : Survey data from an ongoing cohort study of gynecologic cancer survivors were used (n=154). Relationships between fear of cancer recurrence measured by the 6-item Cancer Worry Scale in the most recent survey and psychosocial factors (cancer-related distress, depression, anxiety, hopelessness, and posttraumatic growth) [...]
Analyses économiques et systèmes de soins (2)
Menée aux Etats-Unis à partir de données portant sur 964 aidants de patients afro-américains ayant survécu à un cancer, cette étude analyse leurs difficultés financières et les coûts associés à leur situation d'aidant
Caregiver costs and financial burden in caregivers of African American cancer survivors
Menée aux Etats-Unis à partir de données portant sur 964 aidants de patients afro-américains ayant survécu à un cancer, cette étude analyse leurs difficultés financières et les coûts associés à leur situation d'aidant
Caregiver costs and financial burden in caregivers of African American cancer survivors
Hastert, Theresa A. ; Kyko, Jaclyn M. ; Ruterbusch, Julie J. ; Robinson, Jamaica R. M. ; Kamen, Charles S. ; Beebe-Dimmer, Jennifer L. ; Nair, Mrudula ; Thompson, Hayley S. ; Schwartz, Ann G.
Purpose : People with cancer commonly rely on loved ones as informal caregivers during and after treatment. Costs related to caregiving and their association with caregiver financial burden are not well understood. Methods : Results include data from 964 caregivers of African American cancer survivors in the Detroit Research on Cancer Survivors (ROCS) cohort. Caregiving costs include those related to medications, logistics (e.g., transportation), and medical bills. Financial burden measures [...]
Cette étude analyse le rapport coût-efficacité de la mise en oeuvre des recommandations sur le dépistage du cancer du sein comportant une mammographie et une IRM du sein chez les femmes ayant survécu à un lymphome hodgkinien pédiatrique et ayant reçu une radiothérapie du thorax
Health Benefits and Cost-Effectiveness of Children's Oncology Group Breast Cancer Screening Guidelines for Chest-Irradiated Hodgkin Lymphoma Survivors
Cette étude analyse le rapport coût-efficacité de la mise en oeuvre des recommandations sur le dépistage du cancer du sein comportant une mammographie et une IRM du sein chez les femmes ayant survécu à un lymphome hodgkinien pédiatrique et ayant reçu une radiothérapie du thorax
Health Benefits and Cost-Effectiveness of Children's Oncology Group Breast Cancer Screening Guidelines for Chest-Irradiated Hodgkin Lymphoma Survivors
F. Lennie Wong ; Janie M. Lee ; Wendy M. Leisenring ; Joseph P. Neglia ; Rebecca M. Howell ; Susan A. Smith ; Kevin C. Oeffinger ; Chaya S. Moskowitz ; Tara O. Henderson ; Ann Mertens ; Paul C. Nathan ; Yutaka Yasui ; Wendy Landier ; Gregory T. Armstrong ; Leslie L. Robison ; Smita Bhatia
PURPOSE : To evaluate the outcomes and cost-effectiveness of the Children's Oncology Group Guideline recommendation for breast cancer (BC) screening using mammography (MAM) and breast magnetic resonance imaging (MRI) in female chest-irradiated childhood Hodgkin lymphoma (HL) survivors. Digital breast tomosynthesis (DBT), increasingly replacing MAM in practice, was also examined. METHODS : Life years (LYs), quality-adjusted LYs (QALYs), BC mortality, health care costs, and false-positive screen [...]
Sensibilisation et communication (1)
A partir d'une revue systématique de la littérature, cette étude évalue les interventions pour aider les patients atteints d'un cancer à décider de leur participation à un essai clinique
Interventions supporting cancer patients in making decisions regarding participation in clinical trials - a systematic review
A partir d'une revue systématique de la littérature, cette étude évalue les interventions pour aider les patients atteints d'un cancer à décider de leur participation à un essai clinique
Interventions supporting cancer patients in making decisions regarding participation in clinical trials - a systematic review
Hillersdal, Line ; Nielsen, Zandra Engelbak ; Nørmark, Ane Taudorf ; Knoop, Ann ; Piil, Karin
Objectives : Existing research on the perspectives of patients with cancer and health care professionals indicates that patient decision making on cancer clinical trial participation is a complex process and may be poorly understood, possibly compromising their decision to participate. This systematic review investigates interventions that support patients in their decision-making processes regarding whether to participate or not and assesses the qualities of the interventions, measures used [...]