Menée au Japon entre 1995 et 1999 par questionnaire auprès de 42 328 hommes et 48 176 femmes (durée moyenne de suivi : 15 ans), cette étude analyse, en fonction du sexe, l'association entre une consommation de différents types de viande et le risque de cancer de l'estomac (2 701 cas)

Meat consumption and gastric cancer risk: The Japan Public Health Center-based Prospective Study

Wilunda, Calistus ; Yamaji, Taiki ; Iwasaki, Motoki ; Inoue, Manami ; Tsugane, Shoichiro ; Sawada, Norie

The association of meat consumption with gastric cancer is inconclusive.We examined the association of meat consumption with gastric cancer risk among Japanese males and females.This cohort study included 42,328 male and 48,176 female participants of the Japan Public Health Center-based Prospective Study, who were aged 45 to 74 y at recruitment. Dietary intake data were collected from January 1, 1995 to December 31, 1999 using a validated food frequency questionnaire. HRs and 95% CIs for [...]

Menée au Japon par questionnaire auprès de 48 222 hommes (âge : 40-69 ans ; durée moyenne de suivi : 18,8 ans), cette étude analyse l'association entre une consommation de café et le risque de cancer de la prostate (1 617 cas)

Association between coffee consumption and risk of prostate cancer in Japanese men: a population-based cohort study in Japan

Imatoh, Takuya ; Sawada, Norie ; Yamaji, Taiki ; Iwasaki, Motoki ; Inoue, Manami ; Tsugane, Shoichiro

Background: Although numerous epidemiological studies have examined whether coffee consumption is associated with prostate cancer risk, the results remain controversial. Moreover, there are few studies in Asian populations. Therefore, we investigated the association between coffee consumption and the risk of prostate cancer in a large-scale prospective population-based cohort study in Japan. Methods: Study subjects were 48,222 men (40 to 69 years) who completed a questionnaire that included [...]

Menée à partir de données 2012-2014 des cohortes "the Nurses’ Health Studies" et "the Health Professionals Follow-Up Study" portant sur 214 797 participants (âge moyen : 43 et 54 ans), cette étude analyse l'association entre des bactéries impliquées dans le métabolisme du soufre d'origine alimentaire et le risque de cancer colorectal (3 217 cas), en fonction du sexe

Association Between the Sulfur Microbial Diet and Risk of Colorectal Cancer

Wang, Yiqing ; Nguyen, Long H. ; Mehta, Raaj S. ; Song, Mingyang ; Huttenhower, Curtis ; Chan, Andrew T.

Sulfur-metabolizing bacteria that reduce dietary sulfur to hydrogen sulfide have been associated with colorectal cancer (CRC). However, there are limited studies investigating the association between diet and sulfur-metabolizing bacteria in the development of CRC.To develop a dietary score that correlates with gut sulfur–metabolizing bacteria and to examine its association with CRC risk.This prospective cohort study included data from the Health Professionals Follow-up Study (1986-2014), [...]

A partir d'une revue systématique de la littérature publiée jusqu'en mars 2020 (23 études), cette méta-analyse évalue l'association entre une exposition professionnelle ou non aux gaz d'échappement diesel et le risque de lymphome non hodgkinien

Diesel exhaust exposure and risk of non-Hodgkin lymphoma: a meta-analysis

Vilardi, Valeria ; Boffetta, Paolo

Objective: We aimed at carrying out a systematic review and meta-analysis of epidemiological studies on the association between occupational and non-occupational exposures to diesel exhaust and risk of non-Hodgkin lymphoma. Methods: We conducted a systematic search of the literature and identified 16 cohort studies and 7 case-control studies that analyzed non-Hodgkin lymphoma alone or combined with Hodgkin lymphoma or multiple myeloma, from which we extracted 29 independent risk estimates. We [...]

Menée sur la période 2002-2014 auprès de 2 461 patients atteints d'un lymphome et 2 253 témoins, cette étude analyse l'association entre la vaccination contre l'hépatite A, l'hépatite B, la fièvre jaune ou la grippe et le risque de développer un lymphome, par sous-type

Vaccination History and Risk of Lymphoma and Its Major Subtypes

Kleinstern, Geffen ; Larson, Melissa C ; Ansell, Stephen M ; Thompson, Carrie A ; Nowakowski, Grzegorz S ; Call, Timothy G ; Robinson, Dennis P ; Maurer, Matthew J ; Mwangi, Raphael ; Feldman, Andrew L ; Kay, Neil E ; Novak, Anne J ; Habermann, Thomas M ; Slager, Susan L ; Cerhan, James R

Background: Vaccinations have been hypothesized to play a role in lymphoma etiology, but there are few studies, mixed results and limited data on lymphoma subtypes. Herein, we investigate the association of vaccinations with risk of major lymphoma subtypes. Methods: We studied 2461 lymphoma cases and 2253 controls enrolled from 2002-2014. Participants self-reported history of vaccinations against hepatitis A, hepatitis B, yellow fever and influenza. Polytomous logistic regression was used to [...]

A partir d'une revue systématique de la littérature publiée jusqu'en juin 2020 (37 études), cette méta-analyse évalue l'association entre l'indice de masse corporelle autour de l'âge de 18 ans et le risque de cancer du sein (39 733 patientes), de l'endomètre (4 539 patientes) et de l'ovaire (2 692 patientes)

Early-life body mass index and risks of breast, endometrial, and ovarian cancers: a dose–response meta-analysis of prospective studies

Byun, Dohyun ; Hong, SungEun ; Ryu, Seaun ; Nam, Yeonju ; Jang, Hajin ; Cho, Yoonkyoung ; Keum, NaNa ; Oh, Hannah

Background: The evidence for the associations between early-life adiposity and female cancer risks is mixed. Little is known about the exact shape of the relationships and whether the associations are independent of adult adiposity. Methods: We conducted dose–response meta-analyses of prospective studies to summarise the relationships of early-life body mass index (BMI) with breast, endometrial, and ovarian cancer risks. Pubmed and Embase were searched through June 2020 to identify relevant [...]

Menée à partir de données des registres américains des cancers et de données 2011-2020 d'une étude portant sur 480 porteurs d'un variant constitutionnel pathogène ou probablement pathogène de TP53, cette étude analyse l'incidence du cancer et les caractéristiques de la maladie dans cette population

Cancer incidence, patterns, and genotype-phenotype associations in individuals with pathogenic or likely pathogenic germline TP53 variants: an observational cohort study

de Andrade, Kelvin César ; Khincha, Payal P. ; Hatton, Jessica N. ; Frone, Megan N. ; Wegman-Ostrosky, Talia ; Mai, Phuong L. ; Best, Ana F. ; Savage, Sharon A.

Background: Li-Fraumeni syndrome, caused primarily by pathogenic or likely pathogenic germline TP53 variants, is a rare, variably penetrant, cancer predisposition syndrome with very high risks of cancer starting in childhood, including the risk of multiple primary malignancies over an individual's lifespan. We aimed to characterise and quantify cancer incidence, patterns, and genotype–phenotype associations in individuals with pathogenic or likely pathogenic germline TP53 variants. Methods: [...]

Menée entre 2016 et 2020 auprès de 1 985 témoins et 2 200 patients atteints d'un cancer de la prostate, cette étude multicentrique analyse l'association entre l'obésité générale ou abdominale et le risque de cancer de la prostate chez les hommes africains

Overall and central obesity and prostate cancer risk in African men

Agalliu, Ilir ; Lin, Wei-Kaung Jerry ; Zhang, Janice S. ; Jacobson, Judith S. ; Rohan, Thomas E. ; Adusei, Ben ; Snyper, Nana Yaa F. ; Andrews, Caroline ; Sidahmed, Elkhansa ; Mensah, James E. ; Biritwum, Richard ; Adjei, Andrew A. ; Okyne, Victoria ; Ainuson-Quampah, Joana ; Fernandez, Pedro ; Irusen, Hayley ; Odiaka, Emeka ; Folasire, Oluyemisi Folake ; Ifeoluwa, Makinde Gabriel ; Aisuodionoe-Shadrach, Oseremen I. ; Nwegbu, Maxwell Madueke ; Pentz, Audrey ; Chen, Wenlong Carl ; Joffe, Maureen ; Neugut, Alfred I. ; Diallo, Thierno Amadou ; Jalloh, Mohamed ; Rebbeck, Timothy R. ; Adebiyi, Akindele Olupelumi ; Hsing, Ann W.

Purpose: African men are disproportionately affected by prostate cancer (PCa). Given the increasing prevalence of obesity in Africa, and its association with aggressive PCa in other populations, we examined the relationship of overall and central obesity with risks of total and aggressive PCa among African men. Methods: Between 2016 and 2020, we recruited 2,200 PCa cases and 1,985 age-matched controls into a multi-center, hospital-based case–control study in Senegal, Ghana, Nigeria, and South [...]