A partir d'une revue systématique de la littérature (35 études), cette étude identifie les besoins en soins pour améliorer la qualité de la vie sexuelle des patients atteints d'un cancer ou ayant survécu à la maladie (âge : 18-39 ans)

Sexual health-related care needs among young adult cancer patients and survivors: a systematic literature review

Lehmann, Vicky ; Laan, Ellen T. M. ; Den Oudsten, Brenda L.

Purpose : Young adult cancer patients and survivors have age-specific care needs, but care needs related to sexual health are poorly understood. A systematic literature review was conducted to examine sexual health-related care needs among patients/survivors diagnosed with cancer during young adulthood (age: 18–39 years). The prevalence and types needs were assessed along with associated patient factors. Methods : Four major databases were screened to identify relevant studies, which were also [...]

Menée aux Etats-Unis par questionnaire auprès de patients atteints d'un cancer de la tête et du cou et de leurs aidants, cette étude analyse les disparités dans leurs perceptions de la qualité de vie du patient après la fin des traitements anticancéreux

Disparity of perception of quality of life between head and neck cancer patients and caregivers

Kassir, Zachary M. ; Li, Jinhong ; Harrison, Christine ; Johnson, Jonas T. ; Nilsen, Marci L.

Background : Caregivers are invaluable sources of support for individuals recovering from head and neck cancer (HNC). Accordingly, minimizing caregiver distress is essential to promote the well-being of both caregivers and their patients. This study assessed if psychosocial distress (i.e., anxiety and depression) among HNC caregivers is associated with a difference in how caregivers and their patients perceive patients’ quality of life (QOL) after treatment completion. Methods : Caregivers’ and [...]

Menée en Serbie à partir de données du registre national des cancers, cette étude analyse l'évolution, sur la période 1999-2018, de l'incidence des cancers d'origine primitive inconnue et de la mortalité, puis évalue l'association entre le ratio incidence/mortalité et l'indice de développement humain

Cancer of unknown primary - incidence, mortality trend, and mortality-to-incidence ratio is associated with human development index in Central Serbia, 1999–2018: Evidence from the national cancer registry

Ignjatović, Aleksandra ; Stojanović, Miodrag ; Milošević, Zoran ; Anđelković Apostolović, Marija ; Filipović, Tamara ; Rančić, Nataša ; Marković, Roberta ; Topalović, Marija ; Stojanović, Dijana ; Otašević, Suzana

Objectives : The aim was to estimate the trend of incidence, mortality and mortality-to-incidence ratio (MIR) in Central Serbia in 1999–2018 and its possible association with the c(HDI). Methods : In this study, cancer of unknown primary (CUP) was included as C77-C80 codes. Trend analysis was performed in the Joinpoint Regression Programme version 4.8.0.1. HDI combines life expectancy, educational attainment and gross national income. HDI values for Serbia are extracted from the global bank [...]

Menée aux Etats-Unis à partir des données d'une enquête nationale conduite sur la période 2002-2018, cette étude analyse la présence de maladies chroniques et de comorbidités chez 30 728 adultes ayant survécu à un cancer

Chronic comorbid conditions among adult cancer survivors in the United States: Results from the National Health Interview Survey, 2002-2018

Jiang, Changchuan ; Deng, Lei ; Karr, Matthew A. ; Wen, Yumeng ; Wang, Qian ; Perimbeti, Stuthi ; Shapiro, Charles L. ; Han, Xuesong

Background : Cancer survivors develop other chronic medical conditions because of shared risk factors and delayed effects of cancer treatment. This study investigated trends in the prevalence of chronic diseases and estimated their population sizes among adult cancer survivors in the United States from 2002 to 2018. Methods : Using 2002-2018 National Health Interview Survey data, this study calculated the age-sex-race/ethnicity–adjusted prevalences and estimated the population sizes for the [...]

Menée à partir des données du registre irlandais des cancers portant sur 3 704 patients pédiatriques atteints d'un cancer sur la période 1994-2012 (âge au diagnostic : 0-19 ans), cette étude analyse les disparités socioéconomiques dans les traitements anticancéreux reçus

Social inequalities in treatment receipt for childhood cancers in Ireland: a population-based analysis

Molcho, Michal ; Thomas, Audrey A ; Walsh, Paul M ; Skinner, Roderick ; Sharp, Linda

Treatment advances over the past five decades have resulted in significant improvements in survival from childhood cancer. Although survival rates are relatively high, social disparities in outcomes have been sometimes observed. In a population-based study, we investigated social inequalities by sex and deprivation in treatment receipt in childhood cancer in Ireland. Cancers incident in people aged 0-19 during 1994-2012 and treatments received were abstracted from the National Cancer Registry [...]

Menée aux Etats-Unis à partir de données portant sur 410 000 adultes, cette étude prospective analyse l'association entre l'âge au début du tabagisme et lors de la cessation et la mortalité par cancer

Association of Smoking Initiation and Cessation Across the Life Course and Cancer Mortality: Prospective Study of 410 000 US Adults

Thomson, Blake ; Emberson, Jonathan ; Lacey, Ben ; Lewington, Sarah ; Peto, Richard ; Islami, Farhad

Smoking remains the leading cause of cancer mortality in the US. Prior research has shown that smokers who start younger have greater mortality risk than those who start later, and quitting (especially at younger ages) substantially reduces that risk. However, the relevance of age at smoking initiation and cessation to cancer mortality in contemporary populations, particularly across the life course, is not well established.

Menée à partir des données des registres américains des cancers et de la base Medicare portant sur 2 686 patients âgés de plus de 65 ans et atteints d'un lymphome hodgkinien diagnostiqué sur la période 2000-2013 (âge moyen : 75,7 ans), cette étude de cohorte analyse l'association entre l'intensité des différents traitements reçus et la mortalité spécifique à 3 ans

Association of Treatment Intensity With Survival in Older Patients With Hodgkin Lymphoma

Rodday, Angie Mae ; Hahn, Theresa ; Kumar, Anita J. ; Lindenauer, Peter K. ; Friedberg, Jonathan W. ; Evens, Andrew M. ; Parsons, Susan K.

Importance : Hodgkin lymphoma is an aggressive blood cancer that is highly curable in younger patients who receive multiagent chemotherapy. Worse survival in older patients may reflect less-aggressive treatment, competing risks of death, or different disease biological factors. Objective :To examine the association between treatment intensity and cause-specific mortality among older adults with Hodgkin lymphoma. Design, Setting, and Participants :This was a population-based cohort study of [...]

Menée au Danemark, cette étude analyse l'évolution, sur la période 1997-2018, de l'incidence des néoplasies intraépithéliales de haut grade du pénis et du carcinome épidermoïde du pénis, ainsi que l'évolution de la survie relative à 5 ans et de la mortalité

Incidence of penile intraepithelial neoplasia and incidence and survival of penile cancer in Denmark, 1997 to 2018

Olesen, Tina Bech ; Sand, Freja L. ; Aalborg, Gitte L. ; Munk, Christian ; Kjaer, Susanne K.

Purpose : Squamous cell carcinoma (SCC) of the penis is rare. Some studies have suggested that the incidence is increasing but the available literature is equivocal. We examined the incidence of high-grade penile intraepithelial neoplasia (PeIN), the incidence and 5-year relative survival as well as mortality of penile SCC in Denmark over the latest 20 years. Methods : New cases of high-grade PeIN and penile cancer were identified from high-quality nationwide registries. Age-standardized [...]

Menée à partir des données des registres américains des cancers sur la période 2000-2018, cette étude analyse l'évolution de l'incidence du cancer du pancréas, en fonction de l'âge et du sexe du patient

Incidence of Pancreatic Cancer by Age and Sex in the US, 2000-2018

Gaddam, Srinivas ; Abboud, Yazan ; Oh, Janice ; Samaan, Jamil S. ; Nissen, Nicholas N. ; Lu, Shelly C. ; Lo, Simon K.

Pancreatic cancer is the fourth leading cause of cancer death with a 5-year survival rate of approximately 10%.1 Noncomparative data from 2013 showed increasing incidence of pancreatic cancer in older White women and men and in younger non-Hispanic White women.2 However, there are limited data on recent trends in pancreatic cancer incidence. The aim of this study was to perform an age- and sex-specific time trend analysis of pancreatic cancer incidence rates. Methods : Pancreatic cancer [...]

Menée aux Etats-Unis par enquête auprès de médecins oncologues (227 répondants), cette étude analyse leurs connaissances et leurs pratiques concernant les conseils génétiques et l'utilisation de tests génétiques pour leurs patientes atteintes d'un cancer du sein, selon l'origine ethnique de la patiente

Genetic Counseling and Testing in African American Patients With Breast Cancer: A Nationwide Survey of US Breast Oncologists

Foluso O. Ademuyiwa ; Patricia Salyer ; Yu Tao ; Jingqin Luo ; Whitney L. Hensing ; Abisola Afolalu ; Lindsay L. Peterson ; Katherine Weilbaecher ; Ashley J. Housten ; Ana A. Baumann ; Monica Desai ; Susan Jones ; Erin Linnenbringer ; Jennifer Plichta ; Laura Bierut

PURPOSE : To determine if physicians' self-reported knowledge, attitudes, and practices regarding genetic counseling and testing (GCT) vary by patients' race. METHODS : We conducted a nationwide 49-item survey among breast oncology physicians in the United States. We queried respondents about their own demographics, clinical characteristics, knowledge, attitudes, practices, and perceived barriers in providing GCT to patients with breast cancer. RESULTS : Our survey included responses from 277 [...]

Menée aux Etats-Unis à partir de données portant sur 200 patients atteints d'un carcinome ou d'un adénocarcinome du canal salivaire, cette étude rétrospective analyse l'efficacité, du point de vue du taux de réponse objective, de la survie sans récidive, de la survie sans progression et de la survie globale, de différentes stratégies thérapeutiques (traitements systémiques ou localisés, contexte curatif ou palliatif)

Treatment patterns and outcomes of palliative systemic therapy in patients with salivary duct carcinoma and adenocarcinoma, not otherwise specified

Sousa, Luana G. ; Wang, Kaiwen ; Torman, Danice ; Binks, Bailee J. ; Rubin, Maria Laura ; Andersen, Clark R. ; Lewis, Whitney E. ; Rivera, Melvin J. ; Kaya, Diana ; El-Naggar, Adel K. ; Hanna, Ehab Y. ; Esmaeli, Bita ; Frank, Steven J. ; Bell, Diana ; Glisson, Bonnie S. ; Rodon, Jordi ; Meric-Bernstam, Funda ; Lee, J. Jack ; Ferrarotto, Renata

Background : Salivary duct carcinoma (SDC) and adenocarcinoma, not otherwise specified (adeno-NOS), are rare salivary gland cancers. Data on the efficacy of systemic therapy for these diseases are limited. Methods : Data were retrospectively collected from patients seen at The University of Texas MD Anderson Cancer Center during 1990 to 2020. Objective response rate (ORR) was assessed per RECIST v1.1. Recurrence-free survival (RFS), progression-free survival (PFS), and overall survival (OS) [...]

Menée à partir de données des registres américains des cancers portant sur 96 948 patients ayant survécu à un cancer pédiatrique diagnostiqué entre 1975 et 2016, cette étude analyse le risque de suicide (89 décès par suicide)

Risk of suicide among individuals with a history of childhood cancer

Barnes, Justin M. ; Johnson, Kimberly J. ; Grove, Jeremy L. ; Srivastava, Amar J. ; Osazuwa-Peters, Nosayaba ; Perkins, Stephanie M.

BACKGROUND : Previous studies have described suicidal ideation among survivors of childhood cancer, but small numbers of events limit the understanding of suicide risk. The objectives of this study were to assess whether childhood cancer survivors are at increased risk of suicide in comparison with the general population and to determine risk factors associated with risk in a population-based cohort. METHODS : First primary malignancies among individuals aged 0 to 19 years from 1975 to 2016 [...]

Mené sur 176 patients ayant survécu à un cancer, cet essai randomisé évalue l'intérêt d'un programme en ligne destiné à améliorer leur sentiment d'auto-efficacité dans la prise en charge de leur santé

Cancer health self-efficacy improvement in a randomized controlled trial

Leach, Corinne R. ; Hudson, Shawna V. ; Diefenbach, Michael A. ; Wiseman, Kara P. ; Sanders, Amy ; Coa, Kisha ; Chantaprasopsuk, Sicha ; Stephens, Robert L. ; Alfano, Catherine M.

Background : eHealth interventions can help cancer survivors self-manage their health outside the clinic. Little is known about how best to engage and assist survivors across the age and cancer treatment spectra. Methods : The American Cancer Society conducted a randomized controlled trial that assessed efficacy of, and engagement with, Springboard Beyond Cancer, an eHealth self-management program for cancer survivors. Intent-to treat analyses assessed effects of intervention engagement for [...]

Menée aux Etats-Unis par enquête téléphonique auprès de 480 patients ayant survécu à un cancer colorectal, cette étude analyse leurs symptômes d'anxiété et de dépression selon leur orientation sexuelle

Anxiety and Depression in Colorectal Cancer Survivors: Are there differences by sexual orientation?

Boehmer, Ulrike ; Ozonoff, Al ; Winter, Michael ; Berklein, Flora ; Potter, Jennifer ; Ceballos, Rachel M. ; Clark, Melissa A.

Objective : To examine sexual minority compared to heterosexual survivors’ health-related anxiety, anxiety, and depression. Methods : Four-hundred-eighty eligible survivors participated in a telephone survey, which measured their anxiety and depression. These survivors were diagnosed with stage I, II, or III colorectal cancer an average of three years prior to the survey and were recruited from four cancer registries. As explanatory factors, we considered individual, social and contextual [...]

Mené sur 75 jeunes couples dont la femme est atteinte d'un cancer du sein, cet essai randomisé évalue l'intérêt d'une intervention dispensée en ligne pour les aider à faire face à la maladie

Couplelinks Online Intervention for Young Couples Facing Breast Cancer: A Randomized Controlled Trial

Fergus, Karen ; Ahmad, Saunia ; Gardner, Sandra ; Ianakieva, Iana ; McLeod, Deborah ; Stephen, Joanne ; Carter, Wendy ; Periera, Amanda ; Warner, Ellen ; Panchaud, Jim

Abstract : Young women with breast cancer and their partners are more distressed than couples who are affected later in life. While dyadic interventions in the context of cancer are promising, there are access barriers, particularly for younger couples. Objective : This study evaluated Couplelinks, a professionally facilitated, web-based program designed to help couples improve their conjoint coping. Method : This RCT employed a waitlist control evaluation of the program. Outcomes included [...]

Menée aux Etats-Unis, cette étude analyse l'utilisation des thérapies ciblées dispensées par voie orale et autorisées par la FDA entre 2011 et 2018, et évalue les coûts de santé

Real-world Use of and Spending on New Oral Targeted Cancer Drugs in the US, 2011-2018

Fu, Mengyuan ; Naci, Huseyin ; Booth, Christopher M. ; Gyawali, Bishal ; Cosgrove, Austin ; Toh, Sengwee ; Xu, Ziyue ; Guan, Xiaodong ; Ross-Degnan, Dennis ; Wagner, Anita K.

Launch prices of new cancer drugs in the US have substantially increased in recent years despite growing concerns about the quantity and quality of evidence supporting their approval by the US Food and Drug Administration (FDA).To assess the use of and spending on new oral targeted cancer drugs among US residents with employer-sponsored insurance between 2011 and 2018, stratified by the strength of available evidence of benefit.In this cross-sectional study, dispensing claims for oral targeted [...]

Cette étude analyse les facteurs associés aux disparités dans l'utilisation des services de télémédecine

Disparities in telehealth use: How should the supportive care community respond?

Dixit, Niharika ; Van Sebille, Ysabella ; Crawford, Gregory B. ; Ginex, Pamela K. ; Ortega, Paz Fernandez ; Chan, Raymond J.

Telehealth use has increased in the setting of the COVID-19 pandemic. However, there are disparities in telehealth use based on age, income, race/ethnicity, low health, digital literacy, and limited English proficiency. There are multilevel barriers to telehealth use at the patient, health systems, telehealth portal, and policy levels. To ensure equity in telehealth services and to leverage these services to maximize the reach of health care services, concerted efforts are needed to design [...]

A partir d'une revue systématique de la littérature, cette étude analyse la fréquence et la qualité de la mesure, dans les essais cliniques, de l'utilisation de produits tabagiques par les patients atteints d'un cancer génito-urinaire

Persistent deficiencies in the measurement and reporting of tobacco use in contemporary genitourinary oncology clinical trials

Zhao, Calvin ; Myrie, Akya ; Feuer, Zachary ; Roberts, Timothy ; Sherman, Scott E. ; Bjurlin, Marc A. ; Matulewicz, Richard S.

Smoking is a causal or contributory factor for nearly all genitourinary cancers and exerts significant influence on treatment, quality of life, and survival outcomes. In order to understand the influence smoking has on the outcomes of contemporary therapies, pertinent smoking-related data must be systematically collected and report. We sought to determine how often and how rigorously smoking status is collected and reported in publications of clinical trials in genitourinary cancers by [...]