Menée à partir de données 1980-2018 des cohortes "the Nurses’ Health Studies" et "the Health Professionals Follow-Up Study" portant sur 180 832 femmes et 45 560 hommes (durée de suivi : 5 873 671 personnes-années), cette étude analyse l'association entre la consommation de fruits à coque (arachide, noix, etc...) et le risque de cancer (44 561 cas), en particulier le cancer du poumon, du sein, de la vessie, de la prostate et le cancer colorectal

Association of nut consumption with risk of total cancer and 5 specific cancers: evidence from 3 large prospective cohort studies

Fang, Zhe ; Wu, You ; Li, Yanping ; Zhang, Xuehong ; Willett, Walter C ; Eliassen, A Heather ; Rosner, Bernard ; Song, Mingyang ; Mucci, Lorelei A ; Giovannucci, Edward L

The associations between nut consumption and cancer risk have not been extensively investigated.We aimed to examine the associations between nut consumption, especially specific types of nuts (peanut, tree nut, walnut, and tree nut other than walnut), and cancer risk. Nut consumption was assessed by FFQ at baseline and updated every 2–4 y in the Nurses’ Health Study (1980–2014), the Nurses’ Health Study II (1991–2015), and the Health Professionals Follow-up Study (1986–2018). We examined the [...]

Menée à partir de données portant sur 101 095 participants (durée médiane de suivi : 10 ans), cette étude chinoise analyse l'association entre une exposition in utero ou au début de l'enfance à la grande famine (1959-1961) et le risque de cancer (3 560 cas) ainsi que la mortalité associée (1 749 décès)

In utero and childhood exposure to the Great Chinese Famine and risk of cancer in adulthood: the Kailuan Study

Zhang, Xinyuan ; Wang, Gang ; Forman, Michele R ; Fu, Qingjiang ; Rogers, Connie J ; Wu, Shouling ; Gao, Xiang

The risk of cancer in adulthood can be influenced by exposure to environmental factors (e.g., food shortage and stress) in early life.This study compared the risk of cancer morbidity and mortality between Chinese adults who were or were not exposed to the Great Chinese Famine (1959–1961) in utero or during early childhood.The Kailuan Study participants (n = 101,095) were classified into 5 famine exposure groups by birth year collected at study baseline (2006–2007): after 1961 (unexposed), [...]

Menée auprès de 512 patientes atteintes d'un cancer du côlon et de 516 témoins, cette étude analyse l'association entre la concentration des hormones sexuelles circulantes et le risque de développer la maladie, puis évalue, à l'aide d'une méta-analyse, la relation dose-effet entre la concentration en oestrone ou en oestradiol et le risque de cancer colorectal, de cancer du côlon et du rectum chez les femmes ménopausées

Endogenous Circulating Sex Hormone Concentrations and Colon Cancer Risk in Postmenopausal Women: A Prospective Study and Meta-Analysis

Mori, Nagisa ; Keski-Rahkonen, Pekka ; Gicquiau, Audrey ; Rinaldi, Sabina ; Dimou, Niki ; Harlid, Sophia ; Harbs, Justin ; Van Guelpen, Bethany ; Aune, Dagfinn ; Cross, Amanda J ; Tsilidis, Konstantinos K ; Severi, Gianluca ; Kvaskoff, Marina ; Fournier, Agnès ; Kaaks, Rudolf ; Fortner, Renée Turzanski ; Schulze, Matthias B ; Jakszyn, Paula ; Sánchez, María-José ; Colorado-Yohar, Sandra M ; Ardanaz, Eva ; Travis, Ruth ; Watts, Eleanor L ; Masala, Giovanna ; Krogh, Vittorio ; Tumino, Rosario ; Sacerdote, Carlotta ; Panico, Salvatore ; de-Mesquita, Bas Bueno- ; Gram, Inger Torhild ; Waaseth, Marit ; Gunter, Marc J ; Murphy, Neil

Observational studies have consistently reported that postmenopausal hormone therapy use is associated with lower colon cancer risk. However, epidemiological studies examining the associations between circulating concentrations of endogenous estrogens and colorectal cancer have reported inconsistent results.We investigated the associations between circulating concentrations of estrone, estradiol, free estradiol, testosterone, free testosterone, androstenedione, dehydroepiandrosterone (DHEA), [...]