Menée à partir de données 2018-2019 d'un registre des cancers canadiens portant sur 175 patients atteints d'un cancer colorectal et âgés de moins de 50 ans, cette étude analyse l'association entre des facteurs médicaux, liés au mode de vie ou à l'alimentation et le risque de développer précocement la maladie

Risk factors for early-onset colorectal cancer: a population-based case–control study in Ontario, Canada

Chang, Vicky C. ; Cotterchio, Michelle ; De, Prithwish ; Tinmouth, Jill

Purpose: There has been an alarming increase in colorectal cancer (CRC) incidence among young adults aged < 50 years, and factors driving this upward trend are unknown. This study investigated associations between various medical, lifestyle, and dietary factors and risk of early-onset CRC (EO-CRC). Methods: A population-based case–control study was conducted in Ontario, Canada during 2018–2019. EO-CRC cases aged 20–49 years (n = 175) were identified from the Ontario Cancer Registry; sex- and [...]

Menée à partir de données 1984-2017 des cohortes "the Nurses’ Health Studies" et "the Health Professionals Follow-Up Study" portant sur 176 916 femmes et 49 885 hommes (durée de suivi : 5 936 386 personnes-années), cette étude analyse l'association entre l'apport alimentaire en flavonoïdes et le risque de gliome (536 cas)

A prospective study of dietary flavonoid intake and risk of glioma in US men and women

Bever, Alaina M ; Cassidy, Aedín ; Rimm, Eric B ; Stampfer, Meir J ; Cote, David J

Flavonoids are a diverse group of plant constituents with demonstrated neuroprotective and anti-tumor effects. Flavonoid intake may decrease the risk of glioma, but the possibility of an association has not yet been investigated in humans.We evaluated the association between dietary flavonoid consumption and the risk of glioma.We followed participants in the female Nurses’ Health Study (1984–2014; n = 81,688) and Nurses’ Health Study II (1991–2017; n = 95,228) and the male Health Professionals [...]

Menée en Chine entre 2018 et 2020 sur 1 053 futurs pères (âge moyen : 33,8 ans), cet essai randomisé évalue l'efficacité, du point de vue de l'abstinence tabagique validée biochimiquement à 6 mois, d'une intervention associant de brefs conseils, un substitut nicotinique et un contact référent

Brief Advice, Nicotine Replacement Therapy Sampling, and Active Referral for Expectant Fathers Who Smoke Cigarettes: A Randomized Clinical Trial

Luk, Tzu Tsun ; Lam, Tai Hing ; Leung, Wing Cheong ; Leung, Kwok-Yin ; Cheung, Ka Wang ; Kwa, Carina ; Siong, Kar-Hung ; Tang, Kwok-Keung ; Lee, Kai-Wan ; Hsieh, Chi Ju ; Wu, Yongda Socrates ; Li, William Ho-Cheung ; Wang, Man Ping

Pregnancy presents an opportunity to engage expectant fathers in smoking cessation, but evidence from randomized clinical trials is scarce.To evaluate the effectiveness of a proactive, combined intervention for smoking cessation in expectant fathers.This pragmatic randomized clinical trial in prenatal clinics in 7 public hospitals in Hong Kong proactively recruited and enrolled 1053 participants from October 10, 2018, to February 8, 2020. Included male adults were 18 years or older, smoked [...]

Cet article passe en revue les études estimant qu'associer le dépistage du cancer du poumon à une intervention de sevrage tabagique pourrait prévenir plus de décès par cancer du poumon que le dépistage seul

Pairing smoking cessation with lung cancer screening may save lives

Fillon, Mike

A new study has found that offering smoking cessation interventions to current smokers simultaneously with lung cancer screenings provides more years of lifesaving benefit than screening alone at very little added expense. The study appeared in the Journal of the National Cancer Institute (JNCI; published online January 23, 2021. doi:10.1093/jnci/djab002). The Centers for Medicare and Medicaid Services and guidelines from national health organizations, including the American Cancer Society, [...]

Menée en mai 2020 auprès de 1 564 participants âgés de 15 à 24 ans, cette étude décrit une méthode d'identification des messages forts permettant de communiquer sur l'utilisation de la cigarette électronique auprès des jeunes

Identifying message themes to prevent e-cigarette use among youth and young adults

Rath, Jessica M. ; Romberg, Alexa R. ; Perks, Siobhan N. ; Edwards, Domonique ; Vallone, Donna M. ; Hair, Elizabeth C.

In 2020, almost 20% of high school students reported current e-cigarette use. Mass media tobacco prevention campaigns are effective for preventing tobacco use among youth and young adults but selecting messages that will have maximum impact on the target audience is a significant challenge for campaign developers. This study describes the method for identification of potential messaging targets for a national anti-vape mass media campaign using criteria proposed by Hornik and Woolf in their [...]