Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
Rechercher des publications
Pour retrouver les publications signalées par Nota Bene Cancer (archives indexées à partir du n°127 du 1" mars 2012) :
Sommaire du n° 491 du 11 juin 2021
Comportements individuels (4)
Menée à partir des données 1990-2019 de 3 625 enquêtes réalisées dans 204 pays, cette étude cartographie la prévalence du tabagisme chez les jeunes dans le monde et analyse leurs comportements tabagiques
Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990-2019: a systematic analysis...
Menée à partir des données 1990-2019 de 3 625 enquêtes réalisées dans 204 pays, cette étude cartographie la prévalence du tabagisme chez les jeunes dans le monde et analyse leurs comportements tabagiques
Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019
Kendrick, Parkes J. ; Reitsma, Marissa B. ; Abbasi-Kangevari, Mohsen ; Abdoli, Amir ; Abdollahi, Mohammad ; Abedi, Aidin ; Abhilash, E. S. ; Aboyans, Victor ; Adebayo, Oladimeji M. ; Advani, Shailesh M. ; Ahinkorah, Bright Opoku ; Ahmad, Sohail ; Ahmadi, Keivan ; Ahmed, Haroon ; Aji, Budi ; Akalu, Yonas ; Akunna, Chisom Joyqueenet ; Alahdab, Fares ; Al-Aly, Ziyad ; Alanezi, Fahad Mashhour ; Alanzi, Turki M. ; Alhabib, Khalid F. ; Ali, Tilahun ; Alif, Sheikh Mohammad ; Alipour, Vahid ; Aljunid, Syed Mohamed ; Alomari, Mahmoud A. ; Amin, Tarek Tawfik ; Amini, Saeed ; Amu, Hubert ; Ancuceanu, Robert ; Anderson, Jason A. ; Andrei, Catalina Liliana ; Andrei, Tudorel ; Ansari-Moghaddam, Alireza ; Antony, Benny ; Anvari, Davood ; Arabloo, Jalal ; Arian, Nicholas D. ; Arora, Monika ; Artanti, Kurnia Dwi ; Asmare, Wondwossen Niguse ; Atnafu, Desta Debalkie ; Ausloos, Marcel ; Awan, Asma Tahir ; Ayano, Getinet ; Aynalem, Getie Lake ; Azari, Samad ; B, Darshan B. ; Badiye, Ashish D. ; Baig, Atif Amin ; Banach, Maciej ; Banerjee, Srikanta K. ; Barker-Collo, Suzanne Lyn ; Bärnighausen, Till Winfried ; Barqawi, Hiba Jawdat ; Basu, Sanjay ; Bayati, Mohsen ; Bazargan-Hejazi, Shahrzad ; Bekuma, Tariku Tesfaye ; Bennett, Derrick A. ; Bensenor, Isabela M. ; Benzian, Habib ; Benziger, Catherine P. ; Berman, Adam E. ; Bhagavathula, Akshaya Srikanth ; Bhala, Neeraj ; Bhardwaj, Nikha ; Bhardwaj, Pankaj ; Bhattacharyya, Krittika ; Bibi, Sadia ; Bijani, Ali ; Biondi, Antonio ; Braithwaite, Dejana ; Brenner, Hermann ; Brunoni, Andre R. ; Burkart, Katrin ; Burugina Nagaraja, Sharath ; Butt, Zahid A. ; Caetano dos Santos, Florentino Luciano ; Car, Josip ; CARRERAS, Giulia ; Castaldelli-Maia, Joao Mauricio ; Cattaruzza, Maria Sofia Sofia ; Chang, Jung-Chen ; Chaturvedi, Pankaj ; Chen, Simiao ; Chido-Amajuoyi, Onyema Greg ; Chu, Dinh-Toi ; Chung, Sheng-Chia ; Ciobanu, Liliana G. ; Costa, Vera Marisa ; Couto, Rosa A. S. ; Dagnew, Baye ; Dai, Xiaochen ; Damasceno, Albertino Antonio Moura ; Damiani, Giovanni ; Dandona, Lalit ; Dandona, Rakhi ; Daneshpajouhnejad, Parnaz ; Darega Gela, Jiregna ; Derbew Molla, Meseret ; Desta, Abebaw Alemayehu ; Dharmaratne, Samath Dhamminda ; Dhimal, Meghnath ; Eagan, Arielle Wilder ; Ebrahimi Kalan, Mohammad ; Edvardsson, Kristina ; Effiong, Andem ; El Tantawi, Maha ; Elbarazi, Iffat ; Esmaeilnejad, Saman ; Fadhil, Ibtihal ; Faraon, Emerito Jose A. ; Farwati, Medhat ; Farzadfar, Farshad ; Fazlzadeh, Mehdi ; Feigin, Valery L. ; Feldman, Rachel ; Filip, Irina ; Filippidis, Filippos ; Fischer, Florian ; Flor, Luisa Sorio ; Foigt, Nataliya A. ; Folayan, Morenike Oluwatoyin ; Foroutan, Masoud ; Gad, Mohamed M. ; GALLUS, Silvano ; Geberemariyam, Biniyam Sahiledengle ; Gebregiorgis, Birhan Gebresillassie ; Getacher, Lemma ; Getachew Obsa, Abera ; Ghafourifard, Mansour ; Ghanei Gheshlagh, Reza ; Ghashghaee, Ahmad ; Ghith, Nermin ; Gil, Gabriela Fernanda ; Gill, Paramjit Singh ; Ginawi, Ibrahim Abdelmageed ; Goharinezhad, Salime ; Golechha, Mahaveer ; Gopalani, Sameer Vali ; GORINI, Giuseppe ; Grivna, Michal ; Guha, Avirup ; Guimarães, Rafael Alves ; Guo, Yuming ; Gupta, Rajat Das ; Gupta, Rajeev ; Gupta, Tarun ; Gupta, Vin ; Hafezi-Nejad, Nima ; Haider, Mohammad Rifat ; Hamadeh, Randah R. ; Hankey, Graeme J. ; Hargono, Arief ; Hay, Simon I. ; Heidari, Golnaz ; Herteliu, Claudiu ; Hezam, Kamal ; Hird, Thomas R. ; Holla, Ramesh ; Hosseinzadeh, Mehdi ; Hostiuc, Mihaela ; Hostiuc, Sorin ; Househ, Mowafa ; Hsiao, Thomas ; Huang, Junjie ; Ibeneme, Charles Ugochukwu ; Ibitoye, Segun Emmanuel ; Ilic, Irena M. ; Ilic, Milena D. ; Inbaraj, Leeberk Raja ; Irvani, Seyed Sina Naghibi ; Islam, Jessica Y. ; Islam, Rakibul M. ; Islam, Sheikh Mohammed Shariful ; Islami, Farhad ; Iso, Hiroyasu ; Itumalla, Ramaiah ; Jaafari, Jalil ; Jain, Vardhmaan ; Jakovljevic, Mihajlo ; Jang, Sung-In ; Jayaram, Shubha ; Jeemon, Panniyammakal ; Jha, Ravi Prakash ; Jonas, Jost B. ; Jürisson, Mikk ; Kabir, Ali ; Kabir, Zubair ; Kalankesh, Leila R. ; Kanchan, Tanuj ; Kandel, Himal ; Kapoor, Neeti ; Karch, Andre ; Karimi, Salah Eddin ; Kebede, Kindie Mitiku ; Kelkay, Bayew ; Kennedy, Ryan David ; Khader, Yousef Saleh ; Khan, Ejaz Ahmad ; Khayamzadeh, Maryam ; Kim, Gyu Ri ; Kimokoti, Ruth W. ; Kivimäki, Mika ; Kosen, Soewarta ; Koulmane Laxminarayana, Sindhura Lakshmi ; Koyanagi, Ai ; Krishan, Kewal ; Kugbey, Nuworza ; Kumar, G. Anil ; Kumar, Nithin ; Kurmi, Om P. ; Kusuma, Dian ; Lacey, Ben ; Landires, Iván ; Lasrado, Savita ; Lauriola, Paolo ; Lee, Doo Woong ; Lee, Yo Han ; Leung, Janni ; Li, Shanshan ; Lin, Hualiang ; Liu, Wei ; Lugo, Alessandra ; Madhava Kunjathur, Shilpashree ; Majeed, Azeem ; Maleki, Afshin ; Malekzadeh, Reza ; Malta, Deborah Carvalho ; Mamun, Abdullah A. ; Manjunatha, Narayana ; Mansouri, Borhan ; Mansournia, Mohammad Ali ; Martini, Santi ; Mathur, Manu Raj ; Mathur, Prashant ; Mazidi, Mohsen ; McKee, Martin ; Medina-Solís, Carlo Eduardo ; Mehata, Suresh ; Mendoza, Walter ; Menezes, Ritesh G. ; Miazgowski, Bartosz ; Michalek, Irmina Maria ; Miller, Ted R. ; Mini, G. K. ; Mirica, Andreea ; Mirrakhimov, Erkin M. ; Mirzaei, Hamed ; Misra, Sanjeev ; Mohammad, Yousef ; Mohammadian-Hafshejani, Abdollah ; Mohammed, Shafiu ; Mokdad, Ali H. ; Molokhia, Mariam ; Monasta, Lorenzo ; Moni, Mohammad Ali ; Moradzadeh, Rahmatollah ; Morrison, Shane Douglas ; Mossie, Tilahun Belete ; Mubarik, Sumaira ; Mullany, Erin C. ; Murray, Christopher J. L. ; Nagaraju, Shankar Prasad ; Naghavi, Mohsen ; Naik, Nitish ; Nalini, Mahdi ; Nangia, Vinay ; Naqvi, Atta Abbas ; Narasimha Swamy, Sreenivas ; Naveed, Muhammad ; Nazari, Javad ; Nduaguba, Sabina O. ; Negoi, Ruxandra Irina ; Neupane Kandel, Sandhya ; Nguyen, Huong Lan Thi ; Nigatu, Yeshambel T. ; Nixon, Molly R. ; Nnaji, Chukwudi A. ; Noubiap, Jean Jacques ; Nowak, Christoph ; Nuñez-Samudio, Virginia ; Ogbo, Felix Akpojene ; Oguntade, Ayodipupo Sikiru ; Oh, In-Hwan ; Olagunju, Andrew T. ; Owolabi, Mayowa O. ; P A, Mahesh ; Pakshir, Keyvan ; Pan, Liping ; Pana, Adrian ; Panagiotakos, Demosthenes ; Panda-Jonas, Songhomitra ; Pandey, Ashok ; Parekh, Utsav ; Park, Eun-Cheol ; Park, Eun-Kee ; Pashazadeh Kan, Fatemeh ; Pathak, Mona ; Pawar, Shrikant ; Pestell, Richard G. ; Pham, Hai Quang ; Pinheiro, Marina ; Pokhrel, Khem Narayan ; Pourshams, Akram ; Prashant, Akila ; Radfar, Amir ; Rahimi-Movaghar, Vafa ; Rahman, Mohammad Hifz Ur ; Rahman, Muhammad Aziz ; Rahmani, Amir Masoud ; Ram, Pradhum ; Rana, Juwel ; Ranabhat, Chhabi Lal ; Rathi, Priya ; Rawaf, David Laith ; Rawaf, Salman ; Rawassizadeh, Reza ; Renzaho, Andre M. N. ; Rezapour, Aziz ; Riaz, Mavra A. ; Roever, Leonardo ; Ronfani, Luca ; Roshandel, Gholamreza ; Roy, Ambuj ; Roy, Bedanta ; Saddik, Basema ; Sahebkar, Amirhossein ; Salehi, Sana ; Salimzadeh, Hamideh ; Samy, Abdallah M. ; Sanabria, Juan ; Santric-Milicevic, Milena M. ; Sao Jose, Bruno Piassi ; Sathian, Brijesh ; Sawhney, Monika ; Saya, Ganesh Kumar ; Schwendicke, Falk ; Seidu, Abdul-Aziz ; Senthil Kumar, Nachimuthu ; Sepanlou, Sadaf G. ; Shafaat, Omid ; Shah, Syed Mahboob ; Shaikh, Masood Ali ; Shannawaz, Mohammed ; Sharafi, Kiomars ; Sheikh, Aziz ; Sheikhbahaei, Sara ; Shigematsu, Mika ; Shiri, Rahman ; Shishani, Kawkab ; Shivakumar, K. M. ; Shivalli, Siddharudha ; Shrestha, Roman ; Siabani, Soraya ; Sidemo, Negussie Boti ; Sigfusdottir, Inga Dora ; Sigurvinsdottir, Rannveig ; Silva, João Pedro ; Singh, Ambrish ; Singh, Jasvinder A. ; Singh, Virendra ; Sinha, Dhirendra Narain ; Skryabin, Valentin Yurievich ; Skryabina, Anna Aleksandrovna ; Soroush, Ali ; Soyiri, Ireneous N. ; Sreeramareddy, Chandrashekhar T. ; Stein, Dan J. ; Steiropoulos, Paschalis ; Stortecky, Stefan ; Straif, Kurt ; Suliankatchi Abdulkader, Rizwan ; Sulo, Gerhard ; Sundström, Johan ; Tabuchi, Takahiro ; Tadesse, Eyayou Girma ; Tamiru, Animut Tagele ; Tareke, Minale ; Tareque, Md Ismail ; Tarigan, Ingan Ukur ; Thakur, Bhaskar ; Thankappan, Kavumpurathu Raman ; Thapar, Rekha ; Tolani, Musliu Adetola ; Tovani-Palone, Marcos Roberto ; Tran, Bach Xuan ; Tripathy, Jaya Prasad ; Tsegaye, Gebiyaw Wudie ; Tymeson, Hayley D. ; Ullah, Saif ; Unim, Brigid ; Updike, Rachel L. ; Uthman, Olalekan A. ; Vacante, Marco ; Vardavas, Constantine ; Venketasubramanian, Narayanaswamy ; Verma, Madhur ; Vidale, Simone ; Vo, Bay ; Vu, Giang Thu ; Waheed, Yasir ; Wang, Yanzhong ; Welding, Kevin ; Werdecker, Andrea ; Whisnant, Joanna L. ; Wickramasinghe, Nuwan Darshana ; Wubishet, Befikadu Legesse ; Yamagishi, Kazumasa ; Yano, Yuichiro ; Yazdi-Feyzabadi, Vahid ; Yeshaw, Yigizie ; Yimmer, Mohammed Zewdu ; Yonemoto, Naohiro ; Yousefi, Zabihollah ; Yu, Chuanhua ; Yunusa, Ismaeel ; Yusefzadeh, Hasan ; Zaman, Muhammed Shahriar ; Zamani, Mohammad ; Zamanian, Maryam ; Zastrozhin, Mikhail Sergeevich ; Zastrozhina, Anasthasia ; Zhang, Jianrong ; Zhang, Zhi-Jiang ; Zhong, Chenwen ; Zuniga, Yves Miel H. ; Gakidou, Emmanuela
Background: Chewing tobacco and other types of smokeless tobacco use have had less attention from the global health community than smoked tobacco use. However, the practice is popular in many parts of the world and has been linked to several adverse health outcomes. Understanding trends in prevalence with age, over time, and by location and sex is important for policy setting and in relation to monitoring and assessing commitment to the WHO Framework Convention on Tobacco Control. Methods: We [...]
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and initiation among young people in 204 countries and territories...
Menée à partir des données 1990-2019 de 3 625 enquêtes réalisées dans 204 pays, cette étude cartographie la prévalence du tabagisme chez les jeunes dans le monde et analyse leurs comportements tabagiques
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and initiation among young people in 204 countries and territories, 1990-2019
Reitsma, Marissa B. ; Flor, Luisa S. ; Mullany, Erin C. ; Gupta, Vin ; Hay, Simon I. ; Gakidou, Emmanuela
Background: Universally, smoking cessation rates among established smokers are poor. Preventing young people from starting use of and becoming addicted to tobacco products remains a key strategy to end the tobacco epidemic. Previous country-specific studies have found that initiation of smoking tobacco use occurs predominantly among young people and have found mixed progress in reducing the prevalence of smoking tobacco use among young people. Current and comparable estimates for all countries [...]
Tobacco use in young people: being emic to end the epidemic
Menée à partir des données 1990-2019 de 3 625 enquêtes réalisées dans 204 pays, cette étude cartographie la prévalence du tabagisme chez les jeunes dans le monde et analyse leurs comportements tabagiques
Tobacco use in young people: being emic to end the epidemic
Kunst, Anton E.
In their Article in The Lancet Public Health, Marissa Reitsma and colleagues report their comprehensive analysis of smoking tobacco use in young people from more than 3000 tobacco surveys from 204 countries and territories around the world. The result is an invaluable overview of an epidemic that causes millions of deaths every year. Their detailed mapping of the prevalence of smoking tobacco use in young people (aged 15–24 years) will be a reference for policy and research in the years to [...]
Menée aux Etats-Unis par enquête auprès de 14 531 élèves de collège ou de lycée, cette étude analyse leur utilisation de la cigarette électronique en 2020
Characteristics of e-Cigarette Use Behaviors Among US Youth, 2020
Menée aux Etats-Unis par enquête auprès de 14 531 élèves de collège ou de lycée, cette étude analyse leur utilisation de la cigarette électronique en 2020
Characteristics of e-Cigarette Use Behaviors Among US Youth, 2020
Wang, Teresa W. ; Gentzke, Andrea S. ; Neff, Linda J. ; Glidden, Emily V. ; Jamal, Ahmed ; Park-Lee, Eunice ; Ren, Chunfeng ; Cullen, Karen A. ; King, Brian A. ; Hacker, Karen A.
Comprehensive surveillance of e-cigarette use behaviors among youth is important for informing strategies to address this public health epidemic.To characterize e-cigarette use behaviors among US youth in 2020.The 2020 National Youth Tobacco Survey, a nationally representative, cross-sectional, school-based survey of middle school (grades 6-8) and high school (grades 9-12) students, was conducted from January 16, 2020, to March 16, 2020. A total of 14 531 students from 180 schools participated [...]
The Decline in e-Cigarette Use Among Youth in the United States—An Encouraging Trend but an Ongoing Public Health Challenge
Menée aux Etats-Unis par enquête auprès de 14 531 élèves de collège ou de lycée, cette étude analyse leur utilisation de la cigarette électronique en 2020
The Decline in e-Cigarette Use Among Youth in the United States—An Encouraging Trend but an Ongoing Public Health Challenge
Choi, Briana M. ; Abraham, Ivo
The 2014 Surgeon General’s report The Health Consequences of Smoking—50 Years of Progress warned that given the then-current rate of cigarette smoking among US youth, 5.6 million individuals younger than 18 years would die prematurely from smoking-related illness, ie, 1 of every 13 youth aged 17 years or younger. Preventing young people from smoking and protecting them from the dual health dangers of nicotine and combustion hinge in good part on disrupting the developmental, familial, social, [...]
Menée en Angleterre sur la période 2011-2020 par enquête auprès de 5 081 adultes fumeurs, cette étude analyse l'évolution de l'utilisation de la cigarette électronique dans des situations où il est interdit de fumer
Smokers’ use of e-cigarettes in situations where smoking is not permitted in England: quarterly trends 2011-2020 and associations with sociodemogra...
Menée en Angleterre sur la période 2011-2020 par enquête auprès de 5 081 adultes fumeurs, cette étude analyse l'évolution de l'utilisation de la cigarette électronique dans des situations où il est interdit de fumer
Smokers’ use of e-cigarettes in situations where smoking is not permitted in England: quarterly trends 2011-2020 and associations with sociodemographic and smoking characteristics
Jackson, Sarah E ; Beard, Emma ; Brown, Jamie
To examine how the proportion of dual users of cigarettes and e-cigarettes who use e-cigarettes in situations where smoking is not permitted has changed since e-cigarettes became popular in England, and to characterise those who do so.Data were from 5,081 adults in England who reported current smoking and current use of e-cigarettes (‘dual users’) participating in a nationally-representative monthly survey between April 2011 and February 2020. We modelled quarterly changes in prevalence of [...]
Menée aux Pays-Bas par enquête auprès de 1 044 participants, cette étude analyse les connaissances concernant l'association entre le papillomavirus humain et le cancer de l'oropharynx
Public awareness of the association between human papillomavirus and oropharyngeal cancer
Menée aux Pays-Bas par enquête auprès de 1 044 participants, cette étude analyse les connaissances concernant l'association entre le papillomavirus humain et le cancer de l'oropharynx
Public awareness of the association between human papillomavirus and oropharyngeal cancer
Verhees, Femke ; Demers, Imke ; Schouten, Leo J ; Lechner, Matt ; Speel, Ernst-Jan M ; Kremer, Bernd
Early diagnosis of human papillomavirus (HPV) associated oropharyngeal cancer (OPC) is associated with improved survival. To achieve early diagnosis, it might be beneficial to increase awareness of the link between HPV and OPC. This increase of awareness could also be an important way to increase vaccination rates. The aim of our study was to explore the current public knowledge in the Netherlands regarding the association of HPV with OPC.An online cross-sectional survey was used and sent by [...]
Vaccins (2)
Menée en Australie auprès de 400 hommes homosexuels, cette étude analyse la prévalence des infections par le papillomavirus humain (HPV) avant et après la mise en oeuvre, en 2013, d'un programme de vaccination quadrivalente pour les garçons en milieu scolaire
Prevalence of human papillomavirus in young men who have sex with men after the implementation of gender-neutral HPV vaccination: a repeated cross-...
Menée en Australie auprès de 400 hommes homosexuels, cette étude analyse la prévalence des infections par le papillomavirus humain (HPV) avant et après la mise en oeuvre, en 2013, d'un programme de vaccination quadrivalente pour les garçons en milieu scolaire
Prevalence of human papillomavirus in young men who have sex with men after the implementation of gender-neutral HPV vaccination: a repeated cross-sectional study
Machalek, Dorothy A. ; Fairley, Christopher K. ; Garland, Suzanne M. ; Tabrizi, Sepehr N. ; Cornall, Alyssa M. ; Hocking, Jane S. ; Bradshaw, Catriona S. ; Chen, Marcus Y. ; Chow, Eric P. F. ; Wigan, Rebecca ; Atchison, Steph ; Balgovind, Prisha ; Murray, Gerald L.
Background: Anal infection with high-risk human papillomavirus (HPV) genotypes 16 and 18 and anal cancer are overrepresented in men who have sex with men (MSM). This study investigated HPV prevalence in young MSM before and after the implementation of a school-based quadrivalent HPV (genotypes 6, 11, 16, and 18) vaccination programme for boys in Australia in 2013. Methods: In this repeated cross-sectional study, MSM aged 16–20 years were recruited from two successive birth cohorts via sexual [...]
Human papillomavirus vaccinations matter!
Menée en Australie auprès de 400 hommes homosexuels, cette étude analyse la prévalence des infections par le papillomavirus humain (HPV) avant et après la mise en
Human papillomavirus vaccinations matter!
van der Sande, Marianne A. B. ; van der Loeff, Maarten F. Schim
In the 20th century, a range of vaccines enabled major medical breakthroughs that helped to prevent disease, protect public health, and reduce inequities in health care. Crucially, once these vaccines had been proven safe and effective, health gains relied on timely delivery and high uptake. Eric Chow and colleagues report in The Lancet Infectious Diseases about the efficacy of male human papillomavirus (HPV) vaccination against the prevalence of high-risk HPV infections in young men who have [...]
Menée en Finlande à partir des données de 2 essais randomisés de phase III portant sur des échantillons de sérum de jeunes filles vaccinées contre le papillomavirus humain, cette étude analyse la persistance des anticorps neutralisants jusqu'à 12 ans après le vaccin, qu'il soit bivalent ou quadrivalent
Sustainability of neutralising antibodies induced by bivalent or quadrivalent HPV vaccines and correlation with efficacy: a combined follow-up anal...
Menée en Finlande à partir des données de 2 essais randomisés de phase III portant sur des échantillons de sérum de jeunes filles vaccinées contre le papillomavirus humain, cette étude analyse la persistance des anticorps neutralisants jusqu'à 12 ans après le vaccin, qu'il soit bivalent ou quadrivalent
Sustainability of neutralising antibodies induced by bivalent or quadrivalent HPV vaccines and correlation with efficacy: a combined follow-up analysis of data from two randomised, double-blind, multicentre, phase 3 trials
Mariz, Filipe Colaço ; Gray, Penelope ; Bender, Noemi ; Eriksson, Tiina ; Kann, Hanna ; Apter, Dan ; Paavonen, Jorma ; Pajunen, Emma ; Prager, Kristina M. ; Sehr, Peter ; Surcel, Helja-Marja ; Waterboer, Tim ; Müller, Martin ; Pawlita, Michael ; Lehtinen, Matti
Background: Quadrivalent and bivalent vaccines against oncogenic human papillomavirus (HPV) are used worldwide with different reported overall efficacies against HPV infections. Although protective concentrations of vaccine-induced antibodies are still not formally defined, we evaluated the sustainability of neutralising antibodies in vaccine trial participants 2–12 years after vaccination and the correlation with reported vaccine efficacy. Methods: We did a follow-up analysis of data from the [...]
Elimination of cervical cancer depends on HPV vaccination and primary HPV screening
Menée en Finlande à partir des données de 2 essais randomisés de phase III portant sur des échantillons de sérum de jeunes filles vaccinées contre le papillomavirus humain, cette étude analyse la persistance des anticorps neutralisants jusqu'à 12 ans après le vaccin, qu'il soit bivalent ou quadrivalent
Elimination of cervical cancer depends on HPV vaccination and primary HPV screening
Harper, Diane M. ; Jimbo, Masahito
WHO has put forth a challenge for the next century to reduce the incidence of cervical cancer globally to fewer than four cases per 100 000 women, a level equated with elimination. Globally, the range of cervical cancer incidence is far from the WHO goal, with one of the lowest human development index (HDI) countries Eswatini at 75·3 cases per 100 000 women, and the higher HDI regions at 10·4 cases per 100 000 women. Historically, cervical cancer incidence has steadily decreased because of [...]