Mené aux Etats-Unis sur 360 patients ayant survécu à un cancer, cet essai randomisé compare l'efficacité, du point de vue de la réduction de la sévérité des douleurs musculo-squelettiques chroniques, de l'électro-acupuncture et de l'acupuncture auriculaire (ou auriculothérapie)

Effectiveness of Electroacupuncture or Auricular Acupuncture vs Usual Care for Chronic Musculoskeletal Pain Among Cancer Survivors: The PEACE Randomized Clinical Trial

Mao, Jun J. ; Liou, Kevin T. ; Baser, Raymond E. ; Bao, Ting ; Panageas, Katherine S. ; Romero, Sally A. D. ; Li, Q. Susan ; Gallagher, Rollin M. ; Kantoff, Philip W.

Importance : The opioid crisis creates challenges for cancer pain management. Acupuncture confers clinical benefits for chronic nonmalignant pain, but its effectiveness in cancer survivors remains uncertain. Objective : To determine the effectiveness of electroacupuncture or auricular acupuncture for chronic musculoskeletal pain in cancer survivors. Design, Setting, and Participants : The Personalized Electroacupuncture vs Auricular Acupuncture Comparativeness Effectiveness (PEACE) trial is a [...]

Menée en France par deux enquêtes transversales auprès de 150 oncologues et de 197 médecins généralistes, cette étude analyse leurs points de vue concernant l'intérêt de l'homéopathie comme soin de support chez des patients atteints d'un cancer

Perceptions of homeopathy in supportive cancer care among oncologists and general practitioners in France

Bagot, J. L. ; Theunissen, I. ; Serral, A.

Objectives : In France, homeopathy is the most frequently used complementary therapy in supportive care in oncology (SCO); its use is steadily increasing. However, data is limited about the perception and relevance of homeopathy by oncologists and general practitioners (GPs) both with and without homeopathic training (HGPs and NHGPs, respectively). Our aim was to evaluate French physicians’ perceptions of homeopathy to clarify its place in SCO through two original observation survey-based [...]

Cette étude passe en revue les enjeux de la prise en charge d'une cachéxie chez les patients atteints d'un cancer du pancréas

Pancreatic cancer cachexia: three dimensions of a complex syndrome

Kordes, Maximilian ; Larsson, Lars ; Engstrand, Lars ; Löhr, J. Matthias

Cancer cachexia is a multifactorial syndrome that is characterised by a loss of skeletal muscle mass, is commonly associated with adipose tissue wasting and malaise, and responds poorly to therapeutic interventions. Although cachexia can affect patients who are severely ill with various malignant or non-malignant conditions, it is particularly common among patients with pancreatic cancer. Pancreatic cancer often leads to the development of cachexia through a combination of distinct factors, [...]

Mené sur 45 patientes ayant survécu à un cancer du sein, cet essai randomisé évalue les facteurs associés à leur adhésion à une intervention d'activité physique de faible ou de haute intensité

Adherence to a lower versus higher intensity physical activity intervention in the Breast Cancer & Physical Activity Level (BC-PAL) Trial

McNeil, Jessica ; Fahim, Mina ; Stone, Chelsea R. ; O’Reilly, Rachel ; Courneya, Kerry S. ; Friedenreich, Christine M.

Purpose : The first aim is to examine adherence to a lower versus higher intensity physical activity (PA) prescription in breast cancer survivors in the Breast Cancer & Physical Activity Level (BC-PAL) Trial. The second aim is to assess associations between baseline characteristics with mean PA adherence in both intervention groups combined. Methods : Forty-five participants were randomized to a 12-week, home-based lower (300 min/week, 40-59% heart rate reserve (HRR)) or higher (150 min/week, [...]

Menée en Espagne à partir de données portant sur 6 512 patientes ayant survécu à long terme à un cancer du sein, cette étude analyse leur utilisation des services de santé sur la péride 2012-2016

Use of health services among long-term breast cancer survivors in Spain: longitudinal study based on real-world data

Jansana, Anna ; Domingo, Laia ; Ibáñez, Berta ; Prados, Alexandra ; Del Cura, Isabel ; Padilla-Ruiz, Maria ; Sanz, Teresa ; Poblador, Beatriz ; Tamayo, Ibai ; Gimeno, Antonio ; Alberquilla, Angel ; Abizanda, Mercè ; Comas, Mercè ; Lanzuela, Manuela ; Burgui, Rossana ; Holgado, Antonio Diaz ; Duarte-Salles, Talita ; Moreno, Conchi ; Louro, Javier ; Baquedano, Javier ; Molina, Cristobal ; del Carmen Martinez, Maria ; Gorricho, Javier ; Redondo, Maximino ; Castells, Xavier ; Sala, Maria

Purpose : This study aimed to evaluate health service utilization in Spain among long-term breast cancer survivors and to compare it with that among women with no history of breast cancer. Methods : Study based on the SURBCAN cohort includes a sample of long-term breast cancer survivors and a sample of women without breast cancer from 5 Spanish regions. Healthcare utilization was assessed through primary care, hospital visits, and tests during the follow-up period (2012 to 2016) by using [...]

Menée aux Pays-Bas sur la période 2008-2018 à partir de données portant sur des patients atteints d'un cancer du poumon non à petites cellules de stade I à III, cette étude analyse l'évolution des stratégies thérapeutiques utilisées

Trends and variations in treatment of stage I-III non-small cell lung cancer from 2008-2018: a nationwide population-based study from the Netherlands

Evers, Jelle ; De Jaeger, Katrien ; Hendriks, Lizza E. L. ; van der Sangen, Maurice ; Terhaard, Chris ; Siesling, Sabine ; De Ruysscher, Dirk ; Struikmans, Henk ; Aarts, Mieke J.

Introduction : This Dutch population-based study nationwide treatment patterns and its variations for stage I-III non-small cell lung cancer (NSCLC). Materials and methods : Patients diagnosed with clinical stage I-III NSCLC in the period 2008-2018 were selected from the Netherlands Cancer Registry. Treatment trends were studied over time and age groups. Use of radiotherapy versus surgery (stage I-II), and concurrent versus sequential chemoradiotherapy (stage III) were analyzed by logistic [...]

Menée à partir de données portant sur 8 900 patientes atteintes d'un cancer du sein de stade I à III, cette étude de cohorte prospective analyse l'association entre une consommation de thé et de café après le diagnostic de la maladie et la mortalité spécifique ainsi que la mortalité toutes causes confondues

Post-diagnostic coffee and tea consumption and breast cancer survival

Farvid, Maryam S. ; Spence, Nicholas D. ; Rosner, Bernard A. ; Willett, Walter C. ; Eliassen, A. Heather ; Holmes, Michelle D.

Background : We examined the role of post-diagnostic coffee and tea consumption in relation to breast cancer-specific and all-cause mortality among women with breast cancer in prospective cohort studies. Methods : We identified 8900 women with stage I–III breast cancer from 1980 through 2010 in the Nurses’ Health Study (NHS) and from 1991 through 2011 in the NHSII. Post-diagnostic coffee and tea consumption was assessed by a validated food frequency questionnaire every 4 years after diagnosis. [...]

Menée à partir des données d'un registre vietnamien des cancers portant sur 5 953 patients atteints d'un cancer de la thyroïde, cette étude analyse les facteurs associés à l'évolution de l'incidence de la maladie sur la période 1996-2015

Trends in incidence and histological pattern of thyroid cancer in Ho Chi Minh City, Vietnam (1996–2015): a population-based study

Pham, Dung X. ; Nguyen, Hien D. ; Phung, An H. T. ; Bui, Tung D. ; Tran, Thach S. ; Tran, Bich N. H. ; Ho-Pham, Lan T. ; Nguyen, Tuan V.

Background : The burden and trend of thyroid cancer in Vietnam have not been well documented. This study aimed to investigate the trends in incidence and histological pattern of thyroid cancer in Ho Chi Minh City from 1996 to 2015. Methods : A population-based study retrieved data from the Ho Chi Minh City Cancer Registry during 1996–2015. Trends in the incidence of thyroid cancer were investigated based on age, gender, and histology for each 5-year period. Annual percentage change (APC) in [...]

Menée à partir des données des registres américains des cancers portant sur 1 907 patients atteints d'un cancer primitif de l'urètre, cette étude analyse les facteurs associés à l'évolution de l'incidence de la maladie sur la période 2004-2016

Incidence rates and contemporary trends in primary urethral cancer

Wenzel, Mike ; Nocera, Luigi ; Collà Ruvolo, Claudia ; Würnschimmel, Christoph ; Tian, Zhe ; Shariat, Shahrokh F. ; Saad, Fred ; Briganti, Alberto ; Tilki, Derya ; Mandel, Philipp ; Becker, Andreas ; Kluth, Luis A. ; Chun, Felix K. H. ; Karakiewicz, Pierre I.

Purpose : We assessed contemporary incidence rates and trends of primary urethral cancer. Methods : We identified urethral cancer patients within Surveillance, Epidemiology and End Results registry (SEER, 2004–2016). Age-standardized incidence rates per 1,000,000 (ASR) were calculated. Log linear regression analyses were used to compute average annual percent change (AAPC). Results : From 2004 to 2016, 1907 patients with urethral cancer were diagnosed (ASR 1.69; AAPC: -0.98%, p = 0.3). ASR [...]

Menée à partir des données des registres américains des cancers portant sur 183 153 patientes atteintes d'un cancer de l'endomètre diagnostiqué entre 2000 et 2017, cette étude estime la survie relative à 5 et à 10 ans ainsi que la mortalité toutes causes confondues

Long-term patterns of excess mortality among endometrial cancer survivors

Anderson, Chelsea ; Bae-Jump, Victoria L ; Broaddus, Russell R. ; Olshan, Andrew F. ; Nichols, Hazel B.

Background: We investigated excess mortality after endometrial cancer using conditional relative survival estimates and standardized mortality ratios (SMRs). Methods: Women diagnosed with endometrial cancer during 2000-2017 (N=183,153) were identified in the Surveillance, Epidemiology, and End Results (SEER) database. SMRs were calculated as observed deaths among endometrial cancer survivors over expected deaths among demographically similar women in the general U.S. population. Five-year [...]

Menée dans 195 pays et territoires sur la période 1990-2017, cette étude analyse l'évolution de l'incidence du cancer de la vésicule biliaire et du cancer des voies biliaires ainsi que les facteurs associés au risque de développer la maladie

The global, regional, and national burden of gallbladder and biliary tract cancer and its attributable risk factors in 195 countries and territories, 1990 to 2017: a systematic analysis for the Global Burden of Disease Study 2017

Ouyang, Guoqing ; Liu, Qiang ; Wu, Yongrong ; Liu, Zhen ; Lu, Wuchang ; Li, Shuai ; Pan, Guangdong ; Chen, Xiang

Background : The global burden of gallbladder and biliary tract cancer (GBTC) is increasing. A comprehensive evaluation of the burden is crucial to improve strategies for GBTC prevention and treatment. Methods : The incidence rates, mortality, and disability‐adjusted life years (DALYs) of GBTC from 1990 to 2017 were extracted from the Global Burden of Diseases Study (GBD) 2017. Estimated annual percent changes (EAPCs) were calculated to quantify GBTC trends during the study period. Results : [...]

Menée en Allemagne par questionnaire auprès de 514 adolescents et jeunes adultes ayant survécu à un cancer (âge moyen au diagnostic : 29,6 ans), cette étude analyse leur utilisation de soins et de services psychosociaux après les traitements anticancéreux ainsi que les facteurs associés à leur satisfaction relative à ces soins

Psychosocial aftercare of adolescent and young adult cancer survivors in Germany: Awareness, utilisation, satisfaction and associated factors

Sender, Annekathrin ; Friedrich, Michael ; Leuteritz, Katja ; Stuckenberg, Erik ; Richter, Diana ; Stöbel-Richter, Yve ; Lordick, Florian ; Geue, Kristina

Aim : This study systematically assesses the awareness of, utilisation of and satisfaction with psychosocial care for adolescents and young adult (AYA) cancer survivors in aftercare. Methods : Survivors between 18 and 39 years were surveyed in aftercare. Awareness of, utilisation of and satisfaction with psychological counselling (PC), social‐legal counselling (SLC) and other psychosocial care (OPC) were measured using self‐developed questionnaires. Multivariate analyses were conducted to [...]

A partir d'une revue systématique de la littérature (26 études), cette méta-analyse évalue l'efficacité d'interventions à base de yoga pour soulager les symptômes de dépression et d'anxiété auto-déclarés par les patients atteints d'un cancer et inclus dans des essais randomisés

Yoga for depression and anxiety symptoms in people with cancer: A systematic review and meta-analysis

Gonzalez, Maria ; Pascoe, Michaela C. ; Yang, Guoyan ; de Manincor, Michael ; Grant, Suzanne ; Lacey, Judith ; Firth, Joseph ; Sarris, Jerome

Objective : Cancer and its treatment can lead to a variety of physical and emotional concerns impacting on those affected, including subclinical or clinical depression and anxiety, which in turn have a significant impact on wellbeing, quality of life and survival. The aim of this review was to evaluate the effect of yoga‐based interventions on self‐reported depression and anxiety symptoms in people with cancer in randomized controlled trials. Method : Six databases were searched to identify [...]

Menée aux Etats-Unis à partir de données portant sur 160 patients atteints d'une leucémie myéloïde aiguë, cette étude analyse les facteurs associés au risque de symptômes de stress post-traumatique

Posttraumatic stress disorder (PTSD) symptoms in patients with acute myeloid leukemia (AML)

Amonoo, Hermioni L. ; LeBlanc, Thomas W. ; Kavanaugh, Alison R. ; Webb, Jason A. ; Traeger, Lara N. ; Jagielo, Annemarie D. ; Vaughn, Dagny M. ; Elyze, Madeleine ; Longley, Regina M. ; Fathi, Amir T. ; Hobbs, Gabriela S. ; Brunner, Andrew M. ; O’Connor, Nina R. ; Luger, Selina M. ; Gustin, Jillian L. ; Bhatnagar, Bhavana ; Horick, Nora K. ; El-Jawahri, Areej

BACKGROUND : Patients with acute myeloid leukemia (AML) receiving intensive chemotherapy face a life‐threatening illness, isolating hospitalization, and substantial physical and psychological symptoms. However, data are limited regarding risk factors of posttraumatic stress disorder (PTSD) symptoms in this population. METHODS : The authors conducted a secondary analysis of data from 160 patients with high‐risk AML who were enrolled in a supportive care trial. The PTSD Checklist‐Civilian Version [...]

Menée aux Etats-Unis auprès de 308 patients âgés atteints d'un cancer et recevant des soins palliatifs à l'extérieur de l'hôpital, cette étude rétrospective analyse les disparités ethniques dans les préférences concernant les soins de fin de vie

Association of Race with End-of-Life Treatment Preferences in Older Adults with Cancer Receiving Outpatient Palliative Care

Sean O'Mahony, ; Sheri Kittelson, ; Paige C. Barker, ; Marvin O. Delgado Guay, ; Yingwei Yao, ; George F. Handzo, ; Harvey M. Chochinov, ; George Fitchett, ; Linda L. Emanuel, ; Diana J. Wilkie

Background: End-of-life discussions and documentation of preferences are especially important for older cancer patients who are at high risk of morbidity and mortality. Objective: To evaluate influence of demographic factors such as religiosity, education, income, race, and ethnicity on treatment preferences for end-of-life care. Methods: A retrospective observational study was performed on baseline data from a multisite randomized clinical trial of Dignity Therapy in 308 older cancer patients [...]

Menée à partir des données des registres américains des cancers et de la base Medicare portant sur 49 715 patients atteints d'un cancer diagnostiqué entre 2011 et 2015, cette étude transversale analyse l'intérêt des mesures permettant d'évaluer la qualité des soins

Evaluation of Reliability and Correlations of Quality Measures in Cancer Care

Keating, Nancy L. ; Cleveland, Jessica L. F. ; Wright, Alexi A. ; Brooks, Gabriel A. ; Meneades, Laurie ; Riedel, Lauren ; Zubizarreta, Jose R. ; Landrum, Mary Beth

Importance : Measurement of the quality of care is important for alternative payment models in oncology, yet the ability to distinguish high-quality from low-quality care across oncology practices remains uncertain. Objective : To assess the reliability of cancer care quality measures across oncology practices using registry and claims-based measures of process, utilization, end-of-life (EOL) care, and survival, and to assess the correlations of practice-level performance across measure and [...]

Menée aux Etats-Unis, cette étude souligne les enjeux liés à l'amélioration des soins de suivi pour les patients ayant survécu à un cancer

Evidence Gaps in Cancer Survivorship Care: A Report from the 2019 National Cancer Institute Cancer Survivorship Workshop

Gallicchio, Lisa ; Tonorezos, Emily ; de Moor, Janet S ; Elena, Joanne ; Farrell, Margaret ; Green, Paige ; Mitchell, Sandra A ; Mollica, Michelle A ; Perna, Frank ; Gottlieb Saiontz, Nicole ; Zhu, Li ; Rowland, Julia ; Mayer, Deborah K

Today, there are more than 16.9 million cancer survivors in the United States; this number is projected to grow to 22.2 million by 2030. While much progress has been made in understanding cancer survivors needs and in improving survivorship care since the seminal 2006 Institute of Medicine report From Cancer Patient to Cancer Survivor: Lost in Transition, there is a need to identify evidence gaps and research priorities pertaining to cancer survivorship. Thus, in April 2019, the National Cancer [...]

A partir d'une revue systématique de la littérature publiée entre 2005 et 2020 (21 études), cette étude analyse les programmes de formation concernant l'après-cancer et dédiés aux médecins généralistes

Outcomes of cancer survivorship education and training for primary care providers: a systematic review

Chan, Raymond J. ; Agbejule, Oluwaseyifunmi Andi ; Yates, Patsy M. ; Emery, Jon ; Jefford, Michael ; Koczwara, Bogda ; Hart, Nicolas H. ; Crichton, Megan ; Nekhlyudov, Larissa

Purpose : To identify published literature regarding cancer survivorship education programs for primary care providers (PCPs) and assess their outcomes. Methods : PubMed, Embase, and CINAHL databases were searched between January 2005 and September 2020. The Quality of Cancer Survivorship Care Framework and Kirkpatrick’s 4-level evaluation model were used to summarize program content and outcomes, respectively. Data extraction and critical appraisal were conducted by two authors. Results : [...]