Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
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Sommaire du n° 477 du 5 février 2021
Lutte contre les cancers
Qualité de vie, soins de support (5)
Menée à Taïwan, à partir de données portant sur 1 109 patients souffrant de maladie thromboembolique veineuse en phase aiguë liée au cancer, cette étude de cohorte compare l'efficacité, du point de vue de la prévention du risque de récidive d'événements thromboemboliques et de saignements, d'une utilisation d'anticoagulants oraux non antivitamine K d’action directe (rivaroxaban, apixaban, édoxaban, ou dabigatran) et d'héparines de bas poids moléculaire (énoxaparine)
Comparison Between Non–vitamin K Antagonist Oral Anticoagulants and Low-Molecular-Weight Heparin in Asian Individuals With Cancer-Associated Venous...
Menée à Taïwan, à partir de données portant sur 1 109 patients souffrant de maladie thromboembolique veineuse en phase aiguë liée au cancer, cette étude de cohorte compare l'efficacité, du point de vue de la prévention du risque de récidive d'événements thromboemboliques et de saignements, d'une utilisation d'anticoagulants oraux non antivitamine K d’action directe (rivaroxaban, apixaban, édoxaban, ou dabigatran) et d'héparines de bas poids moléculaire (énoxaparine)
Comparison Between Non–vitamin K Antagonist Oral Anticoagulants and Low-Molecular-Weight Heparin in Asian Individuals With Cancer-Associated Venous Thromboembolism
Chen, Dong-Yi ; Tseng, Chi-Nan ; Hsieh, Ming-Jer ; Lan, Wen-Ching ; Chuang, Cheng-Keng ; Pang, See-Tong ; Chen, Shao-Wei ; Chen, Tien-Hsing ; Chang, Shang-Hung ; Hsieh, I-Chang ; Chu, Pao-Hsien ; Wen, Ming-Shien ; Chen, Jen-Shi ; Chang, John Wen-Cheng ; See, Lai-Chu ; Huang, Wen-Kuan
Importance : It is unclear whether the clinical benefits associated with non–vitamin K antagonist oral anticoagulants (NOACs) are similar to those associated with low-molecular-weight heparins (LMWHs) in Asian individuals with cancer and acute venous thromboembolism (VTE). Objective : To compare the risk of recurrent thromboembolic events and bleeding associated with use of a NOAC vs use of the LMWH enoxaparin in Asian individuals with cancer-associated VTE. Design, Setting, and Participants : [...]
A partir d'une revue systématique de la littérature (19 essais randomisés), cette méta-analyse évalue l'intérêt de l'art-thérapie (basée sur la musique, la peinture et la danse) pour diminuer les symptômes liés à la maladie (anxiété, dépression, douleur, fatigue, etc.) et améliorer la qualité de vie chez des patientes atteintes d'un cancer du sein ou d'un cancer gynécologique
Role of Arts Therapy in Patients with Breast and Gynecological Cancers: A Systematic Review and Meta-Analysis
A partir d'une revue systématique de la littérature (19 essais randomisés), cette méta-analyse évalue l'intérêt de l'art-thérapie (basée sur la musique, la peinture et la danse) pour diminuer les symptômes liés à la maladie (anxiété, dépression, douleur, fatigue, etc.) et améliorer la qualité de vie chez des patientes atteintes d'un cancer du sein ou d'un cancer gynécologique
Role of Arts Therapy in Patients with Breast and Gynecological Cancers: A Systematic Review and Meta-Analysis
Pengfei Cheng, ; Linlin Xu, ; Junxiang Zhang, ; Wenting Liu, ; Jiaying Zhu
Background: Women with breast and gynecological cancers often experience adverse symptoms such as anxiety, depression, pain, and fatigue. Objective: The purpose of this meta-analysis was to clarify the role of arts therapy (based on music, painting, and dance) in quality of life and reported symptoms among women with breast and gynecological cancers. Methods: Articles on arts therapy were retrieved from relevant electronic databases through to May 2020. The outcomes (quality of life and [...]
Menée en Espagne par questionnaire auprès de 93 patients atteints d'un cancer de stade avancé, cette étude prospective analyse l'effet, sur leur qualité de vie, d'une prise en charge individualisée de la douleur liée à la maladie
Impact of individualized management of breakthrough cancer pain on quality of life in advanced cancer patients: CAVIDIOPAL study
Menée en Espagne par questionnaire auprès de 93 patients atteints d'un cancer de stade avancé, cette étude prospective analyse l'effet, sur leur qualité de vie, d'une prise en charge individualisée de la douleur liée à la maladie
Impact of individualized management of breakthrough cancer pain on quality of life in advanced cancer patients: CAVIDIOPAL study
Rodríguez, Albert Tuca ; Viejo, Miguel Núñez ; Maradey, Pablo ; Canal-Sotelo, Jaume ; Mancilla, Plácido Guardia ; Rivero, Sonia Gutiérrez ; Casillas, Inmaculada Raja ; Abián, María Herrera ; Bermudo, Cristina López
Purpose : The main aim of the study was to assess the impact of individualized management of breakthrough cancer pain (BTcP) on quality of life (QoL) of patients with advanced cancer in clinical practice. Methods : A prospective, observational, multicenter study was conducted in patients with advanced cancer that were assisted by palliative care units. QoL was assessed with the EORTC QLQ-C30 questionnaire at baseline (V0) and after 28 days (V28) of individualized BTcP therapy. Data on [...]
Mené sur 30 patientes afro-américaines atteintes d'un cancer de stade I à III, cet essai de phase II évalue l'intérêt d’un dispositif de refroidissement du cuir chevelu pour prévenir une alopécie induite par la chimiothérapie
Does Scalp Cooling Have the Same Efficacy in Black Patients Receiving Chemotherapy for Breast Cancer?
Mené sur 30 patientes afro-américaines atteintes d'un cancer de stade I à III, cet essai de phase II évalue l'intérêt d’un dispositif de refroidissement du cuir chevelu pour prévenir une alopécie induite par la chimiothérapie
Does Scalp Cooling Have the Same Efficacy in Black Patients Receiving Chemotherapy for Breast Cancer?
Dilawari, Asma ; Gallagher, Christopher ; Alintah, Princess ; Chitalia, Ami ; Tiwari, Shruti ; Paxman, Richard ; Adams-Campbell, Lucile ; Dash, Chiranjeev
Background : The Paxman scalp cooling (SC) device is FDA‐approved for prevention of chemotherapy‐induced alopecia (CIA). Studies report 50%–80% success rates and high patient satisfaction, yet there have been no studies of SC in Black patients. We conducted a phase II feasibility study of Paxman SC with a planned enrollment of 30 Black patients receiving chemotherapy for stage I–III breast cancer. Methods : Black patients who planned to receive ≥4 cycles of chemotherapy with non‐anthracycline [...]
A partir d'une revue systématique de la littérature (9 études), cette étude analyse le risque de lymphoedème, de douleur, de troubles fonctionnels et sensoriels associés à une biopsie du ganglion sentinelle chez des patientes atteintes d'un cancer du sein de stade précoce
Effect of sentinel lymph node biopsy on upper limb function in women with early breast cancer: A systematic review of clinical trials
A partir d'une revue systématique de la littérature (9 études), cette étude analyse le risque de lymphoedème, de douleur, de troubles fonctionnels et sensoriels associés à une biopsie du ganglion sentinelle chez des patientes atteintes d'un cancer du sein de stade précoce
Effect of sentinel lymph node biopsy on upper limb function in women with early breast cancer: A systematic review of clinical trials
Pilger, Taynara Louisi ; Francisco, Daniely Franco ; Candido dos Reis, Francisco Jose
Purpose : Axillary surgery is still essential in the management of early breast cancer. Conservative procedures like sentinel lymph node biopsy (SLNB) are less invasive than the traditional axillary node dissection (ALND). However, some extent of ipsilateral upper limb dysfunction might still occur. This systematic review aimed to describe the incidence of lymphedema, pain, sensory, and motor disorders after SLNB in women with early breast cancer. Methods : We conducted a systematic review of [...]
Observation (4)
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Rapid Transition to Virtual Care during the COVID-19 Epidemic: Experience of a Supportive Care Clinic at a Tertiary Care Cancer Center
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Rapid Transition to Virtual Care during the COVID-19 Epidemic: Experience of a Supportive Care Clinic at a Tertiary Care Cancer Center
Background: COVID-19 pandemic necessitated rapid adoption of telemedicine at our supportive care center (SCC) to ensure continuity of care while maintaining social distancing. Objective: To document the process of transition from in-person to virtual care. Design: The charts of 1744 consecutive patients in our SCC located in the United States were retrospectively reviewed during the four weeks before transition (February 14–March 12), four weeks after transition (March 20–April 16), and [...]
The impact of COVID-19 on systemic anticancer treatment delivery in Scotland
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
The impact of COVID-19 on systemic anticancer treatment delivery in Scotland
Baxter, Mark A. ; Murphy, John ; Cameron, David ; Jordan, Judith ; Crearie, Christine ; Lilley, Christina ; Sadozye, Azmat ; Maclean, Mary ; Hall, Peter ; Phillips, Angela ; Greger, Alex ; Madeleine, Jude ; Petty, Russell D.
Understanding the impact of the COVID-19 pandemic on systemic anticancer therapy delivery (SACT) is crucial to appreciate the short- and long-term consequences for cancer patients and plan future care. Here, we report real-time national SACT delivery data from NHS Scotland. We demonstrate an initial rapid reduction in patient attendance of 28.7% with subsequent rapid recovery following service redesign. The smallest decrease was seen in breast cancer (19.7%), which also had the most rapid [...]
More light on cancer and COVID-19 reciprocal interaction
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
More light on cancer and COVID-19 reciprocal interaction
Brest, Patrick ; Mograbi, Baharia ; Hofman, Paul ; Milano, Gérard
Cancer patients are vulnerable to COVID-19 with consequences on treatment delays and on mortality rate. This Comment explores the interaction between COVID-19 and cancer with attention paid to the modulation by cancer treatments of both ADAM17 and TMPRSS2, the proteases which control ACE2 processing, the SARS-CoV-2 target
Factors associated with psychological distress among patients with breast cancer during the COVID-19 pandemic: a cross-sectional study in Wuhan, China
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Factors associated with psychological distress among patients with breast cancer during the COVID-19 pandemic: a cross-sectional study in Wuhan, China
Chen, Xi ; Wang, Longqiang ; Liu, Lin ; Jiang, Ming ; Wang, Weiming ; Zhou, Xiaorong ; Shao, Jun
Purpose : This study aimed to examine the prevalence of psychological distress and the corresponding risk factors among patients with breast cancer affected by the outbreak of coronavirus disease 2019 (COVID-19). Methods : This cross-sectional, survey-based, region-stratified study was conducted from March 14 to March 21, 2020. An online survey was used to collect the basic characteristics of patients with breast cancer. The degree of depression, anxiety, and insomnia symptoms were assessed [...]
Impact of the COVID-19 pandemic on faecal immunochemical test-based colorectal cancer screening programmes in Australia, Canada, and the Netherland...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Impact of the COVID-19 pandemic on faecal immunochemical test-based colorectal cancer screening programmes in Australia, Canada, and the Netherlands: a comparative modelling study
de Jonge, Lucie ; Worthington, Joachim ; van Wifferen, Francine ; Iragorri, Nicolas ; Peterse, Elisabeth F. P. ; Lew, Jie-Bin ; Greuter, Marjolein J. E. ; Smith, Heather A. ; Feletto, Eleonora ; Yong, Jean H. E. ; Canfell, Karen ; Coupe, Veerle M. H. ; Lansdorp-Vogelaar, Iris
Background : Colorectal cancer screening programmes worldwide have been disrupted during the COVID-19 pandemic. We aimed to estimate the impact of hypothetical disruptions to organised faecal immunochemical test-based colorectal cancer screening programmes on short-term and long-term colorectal cancer incidence and mortality in three countries using microsimulation modelling. Methods : In this modelling study, we used four country-specific colorectal cancer microsimulation models–Policy1-Bowel [...]
Epidemiology and clinical course of SARS-CoV-2 infection in cancer patients in the Veneto Oncology Network: The ROVID Study
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Epidemiology and clinical course of SARS-CoV-2 infection in cancer patients in the Veneto Oncology Network: The ROVID Study
Guarneri, Valentina ; Bassan, Franco ; Zagonel, Vittorina ; Milella, Michele ; Zaninelli, Marta ; Cattelan, Anna Maria ; Vianello, Andrea ; Gori, Stefania ; Aprile, Giuseppe ; Azzarello, Giuseppe ; Chiari, Rita ; Favaretto, Adolfo ; Oliani, Cristina ; Scola, Annamaria ; Pastorelli, Davide ; Mandarà, Marta ; Zustovich, Fable ; Bernardi, Daniele ; Chiarion-Sileni, Vanna ; Morandi, Paolo ; Toso, Silvia ; Di Liso, Elisabetta ; Ziampiri, Stamatia ; Caccese, Mario ; Zampiva, Ilaria ; Puccetti, Oliviero ; Celestino, Michele ; Dieci, Maria Vittoria ; Conte, PierFranco
Introduction : COVID-19 pandemic started in Italy with clusters identified in Northern Italy. The Veneto Oncology Network ROV licensed dedicated guidelines to ensure proper care minimizing the risk of infection in cancer patient. ROVID is a regional registry aimed at describing epidemiology and clinical course of SARS-CoV-2 infection in cancer patients. Materials and methods : Patients with cancer diagnosis and documented SARS-CoV-2 infection are eligible. Data on cancer diagnosis, [...]
Prevalence of Underlying Medical Conditions Associated with Severe COVID-19 Illness in Adult Cancer Survivors in the United States
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Prevalence of Underlying Medical Conditions Associated with Severe COVID-19 Illness in Adult Cancer Survivors in the United States
Jiang, Changchuan ; Robin Yabroff, K ; Deng, Lei ; Perimbeti, Stuthi ; Han, Xuesong
Cancer, and other underlying medical conditions, including chronic obstructive pulmonary disease, heart diseases, diabetes, chronic kidney disease, and obesity, are associated with increased risk of severe COVID-19 illness. We identified 6,411 cancer survivors and 77,748 adults without a cancer history from the 2016-2018 National Health Interview Survey and examined the prevalence and sociodemographic factors associated with these conditions in the US. Most survivors reported having ≥1 of the [...]
Cross-sectional survey of the impact of the COVID-19 pandemic on cancer screening programmes in selected low- and middle-income countries: study fr...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Cross-sectional survey of the impact of the COVID-19 pandemic on cancer screening programmes in selected low- and middle-income countries: study from the IARC COVID-19 impact study group
Villain, Patricia ; Carvalho, Andre L ; Lucas, Eric ; Mosquera, Isabel ; Zhang, Li ; Muwonge, Richard ; Selmouni, Farida ; Sauvaget, Catherine ; Basu, Partha ; IARC COVID-19 impact study group
We conducted a study to document the impact of COVID‐19 pandemic on cancer screening continuum in selected low‐ and middle‐income countries (LMICs). LMICs having an operational cancer control plan committed to screen eligible individuals were selected. Managers/supervisors of cancer screening programmes were invited to participate in an online survey and subsequent in‐depth interview. Managers/supervisors from 18 programmes in 17 countries participated. Lockdown was imposed in all countries [...]
Menée aux Etats-Unis à partir de données portant sur 570 patientes atteintes d'un cancer du sein HR+ non récidivant, cette étude analyse les disparités ethniques dans l'association entre des symptômes auto-déclarés et l'adhésion à un traitement endocrinien adjuvant
Race and Patient-reported Symptoms in Adherence to Adjuvant Endocrine Therapy: A Report from the Women's Hormonal Initiation and Persistence Study
Menée aux Etats-Unis à partir de données portant sur 570 patientes atteintes d'un cancer du sein HR+ non récidivant, cette étude analyse les disparités ethniques dans l'association entre des symptômes auto-déclarés et l'adhésion à un traitement endocrinien adjuvant
Race and Patient-reported Symptoms in Adherence to Adjuvant Endocrine Therapy: A Report from the Women's Hormonal Initiation and Persistence Study
Sheppard, Vanessa B. ; Sutton, Arnethea L ; Hurtado-de-Mendoza, Alejandra ; He, Jun ; Dahman, Bassam ; Edmonds, Megan C. ; Hackney, Mary Helen ; Tadesse, Mahlet G
Background: Adjuvant endocrine therapy (AET) improves outcomes in women with hormone-receptor positive (HR+) breast cancer (BC). Suboptimal AET adherence is common but data are lacking about symptoms and adherence in racial/ethnic minorities. We evaluated adherence by race and the relationship between symptoms and adherence. Methods: The Women's Hormonal Initiation and Persistence (WHIP) study included women diagnosed with non-recurrent HR+ BC who initiated AET. AET adherence was captured using [...]
Menée aux Etats-Unis à partir de données portant sur 5 076 vétérans âgés de plus de 65 ans et atteints d'un myélome multiple traité entre 2004 et 2017, cette étude analyse la multimorbidité puis son association avec la survie globale, les consultations en service d'urgence et les hospitalisations
Defining multimorbidity and its impact in older united states veterans newly treated for multiple myeloma
Menée aux Etats-Unis à partir de données portant sur 5 076 vétérans âgés de plus de 65 ans et atteints d'un myélome multiple traité entre 2004 et 2017, cette étude analyse la multimorbidité puis son association avec la survie globale, les consultations en service d'urgence et les hospitalisations
Defining multimorbidity and its impact in older united states veterans newly treated for multiple myeloma
Fillmore, Nathanael ; DuMontier, Clark ; Yildirim, Cenk ; La, Jennifer ; Epstein, Mara M ; Cheng, David ; Cirstea, Diana ; Yellapragada, Sarvari ; Abel, Gregory A ; Gaziano, J Michael ; Do, Nhan ; Brophy, Mary ; Kim, Dae H ; Munshi, Nikhil C ; Driver, Jane A
Background : Traditional count-based measures of comorbidity are unlikely to capture the complexity of multiple chronic conditions (multimorbidity) in older adults with cancer. We aimed to define patterns of multimorbidity and their impact in older United States Veterans with multiple myeloma (MM). Methods : We measured 66 chronic conditions in 5,076 Veterans age ≥ 65 years newly-treated for MM in the national Veterans Affairs healthcare system from 2004 to 2017. Latent class analysis (LCA) was [...]
Menée à partir de données portant sur 407 témoins et 427 patientes ayant survécu à un cancer du sein non métastatique et âgées de 60 à 98 ans, cette étude analyse les effets du polymorphisme epsilon2 du gène APOE sur leurs capacités cognitives (attention, vitesse de traitement, apprentissage, mémoire,...)
Protective Effects of APOE epsilon2 Genotype on Cognition in Older Breast Cancer Survivors: The Thinking and Living with Cancer Study
Menée à partir de données portant sur 407 témoins et 427 patientes ayant survécu à un cancer du sein non métastatique et âgées de 60 à 98 ans, cette étude analyse les effets du polymorphisme epsilon2 du gène APOE sur leurs capacités cognitives (attention, vitesse de traitement, apprentissage, mémoire,...)
Protective Effects of APOE epsilon2 Genotype on Cognition in Older Breast Cancer Survivors: The Thinking and Living with Cancer Study
Ahles, Tim ; Mandelblatt, Jeanne S ; Cohen, Harvey Jay ; Ahn, Jaeil ; Van Dyk, Kathleen ; Jim, Heather ; Jacobsen, Paul B ; Small, Brent J ; Zhai, Wanting ; Zhou, Xingtao ; Graham, Deena ; McDonald, Brenna C ; Root, James C ; Saykin, Andrew J ; Carroll, Judith E ; Holohan, Kelly Nudelman ; Patel, Sunita K ; Rebeck, G William
Background : Cancer-related cognitive decline (CRCD) has been linked to apolipoprotein E (APOE) gene
Approches psycho-sociales (2)
Menée au Canada à partir des données d'un registre des cancers portant sur 13 095 témoins et 2 619 patients ayant survécu à un cancer du testicule traité par orchidectomie, cette étude de cohorte analyse les facteurs associés à une utilisation de services et de soins psychologiques (durée médiane de suivi : 12 ans)
Long-Term Mental Health Service Utilization Among Survivors of Testicular Cancer: A Population-Based Cohort Study
Menée au Canada à partir des données d'un registre des cancers portant sur 13 095 témoins et 2 619 patients ayant survécu à un cancer du testicule traité par orchidectomie, cette étude de cohorte analyse les facteurs associés à une utilisation de services et de soins psychologiques (durée médiane de suivi : 12 ans)
Long-Term Mental Health Service Utilization Among Survivors of Testicular Cancer: A Population-Based Cohort Study
Michael J. Raphael ; Sumit Gupta ; Xuejiao Wei ; Yingwei Peng ; Claudio N. Soares ; Philippe L. Bedard ; D. Robert Siemens ; Andrew G. Robinson ; Christopher M. Booth
PURPOSE : Testicular cancer survivors may experience mental illness as a consequence of their cancer diagnosis and treatment. METHODS : All incident cases of testicular cancer treated with orchiectomy in Ontario, Canada (2000-2010), were identified using the Ontario Cancer Registry. Cases were matched to controls in a 1:5 ratio on age and geography. Population-level databases were used to identify mental health service use episodes; outpatient use included visits to a general practitioner for a [...]
Menée à partir des données des registres américains des cancers portant sur 10 516 patients âgés et atteints d'un cancer de la vessie diagnostiqué entre 2008 et 2012, cette étude analyse les facteurs associés à une prescription de médicaments psychotropes après le diagnostic de la maladie
Use of Psychotropic Drugs Among Older Patients with Bladder Cancer in the United States
Menée à partir des données des registres américains des cancers portant sur 10 516 patients âgés et atteints d'un cancer de la vessie diagnostiqué entre 2008 et 2012, cette étude analyse les facteurs associés à une prescription de médicaments psychotropes après le diagnostic de la maladie
Use of Psychotropic Drugs Among Older Patients with Bladder Cancer in the United States
Jazzar, Usama ; Bergerot, Cristiane D. ; Shan, Yong ; Wallis, Christopher JD ; Freedland, Stephen J. ; Kamat, Ashish M. ; Tyler, Douglas S. ; Baillargeon, Jacques ; Kuo, Yong-Fang ; Klaassen, Zachary ; Williams, Stephen B.
Objective : Older patients diagnosed with cancer are at increased risk of physical and emotional distress, however, prescription utilization patterns largely remain to be elucidated. Our objective was to comprehensively assess prescription patterns and predictors in older patients with bladder cancer. Methods : A total of 10,516 older patients diagnosed with clinical stage T1‐T4a, N0, M0 bladder urothelial carcinoma from January 1, 2008, to December 31, 2012 from the Surveillance, Epidemiology, [...]
