Menée aux Etats-Unis à partir de données portant sur 600 063 patients atteints d'un cancer gastro-intestinal, cette étude analyse les facteurs associés aux disparités ethniques dans la survie

Understanding Racial Disparities in Gastrointestinal Cancer Outcomes: Lack of Surgery Contributes to Lower Survival in African American Patients

Bliton, John N ; Parides, Michael ; Muscarella, Peter ; Papalezova, Katia T ; In, Haejin

Background: Race/ethnicity-related differences in rates of cancer surgery and cancer mortality have been observed for gastrointestinal (GI) cancers. This study aims to estimate the extent to which differences in receipt of surgery explain racial/ethnic disparities in cancer survival. Methods: The National Cancer Database (NCDB) was used to obtain data for patients diagnosed with stage 1-3 mid-esophageal, distal esophagus/gastric cardia (DEGC), non-cardia gastric, pancreatic, and colorectal [...]

Menée aux Etats-Unis à l'aide de données d'enquêtes réalisées en milieu scolaire entre 2017 et 2020 auprès de 8 660 adolescents, cette étude analyse la prévalence, le risque perçu pour la santé et l'accessibilité des produits de vapotage contenant de la nicotine chez les jeunes

Trends in Use and Perceptions of Nicotine Vaping Among US Youth From 2017 to 2020

Miech, Richard ; Leventhal, Adam ; Johnston, Lloyd ; O’Malley, Patrick M. ; Patrick, Megan E. ; Barrington-Trimis, Jessica

US adolescent nicotine vaping increased at a record pace from 2017 to 2019, prompting new national policies to reduce access to flavors of vaping products preferred by youth.To estimate prevalence, perceived harm, and accessibility of nicotine vaping products among US adolescents from 2017 to 2020.This survey study includes data from Monitoring the Future, which conducted annual, cross-sectional, school-based, nationally representative surveys from 2017 to 2020 of 10th- and 12th-grade students [...]

Menée en France à partir de données 2010-2015 portant sur 44 642 personnes infectées par le VIH, cette étude de cohorte analyse l'évolution de l'incidence des cancers classant SIDA et non classant SIDA par localisation

Spectrum and incidence trends of AIDS and non-AIDS defining cancers between 2010-2015 in the French Dat'AIDS cohort

Poizot-Martin, Isabelle ; Lions, Caroline ; Allavena, Clotilde ; Huleux, Thomas ; Bani-Sadr, Firouze ; Cheret, Antoine ; Rey, David ; Duvivier, Claudine ; Jacomet, Christine ; Ferry, Tristan ; Cabié, André ; Fresard, Anne ; Pugliese, Pascal ; Delobel, Pierre ; Lamaury, Isabelle ; Chirouze, Catherine ; Zaegel-Faucher, Olivia ; Brégigeon, Sylvie ; Rojas Rojas, Teresa ; Obry-Roguet, Véronique ; Makinson, Alain

Background: Cancer risk is higher in people living with HIV (PLWH) compared with the general population and cancers related to age are expected being most prevalent. Methods: We determined the spectrum and incidence rates of AIDS-defining cancers (ADCs), non-AIDS-defining cancers (NADCs) and of lung, Hodgkin lymphoma (HL), head and neck (HNC), colon-rectum, anal, liver, breast, prostate and urinary bladder cancers between 01/2010 and 12/2015 in the French Dat'AIDS cohort. Incidence rates were [...]

Menée à partir des données des registres américains des cancers sur la période 2005-2016 portant sur 5 016 patients atteints d'un mélanome métastatique, cette étude analyse l'évolution du risque de second cancer primitif en lien avec une utilisation d'inhibiteurs de points de contrôle immunitaire (période avant autorisation des inhibiteurs : 2005-2010 ; période après autorisation des inhibiteurs : 2011-2016)

Assessment of Trends in Second Primary Cancers in Patients With Metastatic Melanoma From 2005 to 2016

Deng, Weiye ; Wang, Yifan ; Liu, Xiangyu ; Liu, Jieqiong ; Wang, Liang ; Yang, Zhaogang ; Yang, Mingming ; An, Yi ; Tang, Chad ; Sanford, Nina N. ; Kim, Betty Y. S. ; Jiang, Wen

Importance : To date, the risk of developing second primary cancers (SPCs) after the first primary melanoma has not been studied in the era of immune checkpoint inhibitors (ICIs). Objective : To assess differences in the risk of SPCs in patients with primary melanoma before (2005-2010) and after (2011-2016) the introduction and approval of ICIs. Design, Setting, and Participants : Population-based cohort study using the Surveillance, Epidemiology, and End Results database from January 2005 to [...]

Menée à partir des données des registres américains des cancers sur la période 1975-2015, cette étude analyse l'évolution des facteurs associés à l'incidence de l'adénocarcinome de l'oesophage, à la survie et à la mortalité spécifique

Epidemiology and Outcomes of Young-Onset Esophageal Adenocarcinoma: An Analysis from a Population-Based Database

Codipilly, Don C. ; Sawas, Tarek ; Dhaliwal, Lovekirat ; Johnson, Michele L. ; Lansing, Ramona ; Wang, Kenneth K. ; Leggett, Cadman L. ; Katzka, David A. ; Iyer, Prasad G.

Background: Esophageal adenocarcinoma is a lethal cancer with rising incidence. There are limited data in younger (<50 years) patients with esophageal adenocarcinoma. We aimed to assess time trends in the incidence and outcomes of “young-onset” esophageal adenocarcinoma using a population-based database. Methods: We queried the Surveillance, Epidemiology, and End Results 9 database to identify patients with esophageal adenocarcinoma between 1975 and 2015. Patients were stratified into three age [...]

Menée sur la période 1990-2017, cette étude analyse l'évolution, au niveau international et selon les pays, de la mortalité par cancer du poumon attribuable au tabagisme

Temporal trends of the lung cancer mortality attributable to smoking from 1990 to 2017: a global, regional and national analysis

Yang, Xiaorong ; Man, Jinyu ; Chen, Hui ; Zhang, Tongchao ; Yin, Xiaolin ; He, Qiufeng ; Lu, Ming

Objectives : Understanding the global trend of lung cancer deaths attributable to smoking is crucialfor prioritizing global lung cancer prevention, as well as tobacco control. We assessed patterns of smoking-induced lung cancer deaths at global, regional, and national levels from 1990 to 2017. Materials and methods : We extracted detailed data on lung cancer deaths attributable to smoking from the Global Burden of Disease 2017 Study. The estimated annual percentage change (EAPC)was used to [...]

A partir d'une revue systématique de la littérature (33 études), cette étude analyse le rôle du médecin généraliste dans la prise en charge psychosociale de patients ayant survécu à un cancer

Psychosocial care for cancer survivors: a systematic literature review on the role of General Practitioners

Deckx, Laura ; Chow, Ka Hei ; Askew, Deborah ; van Driel, Mieke L ; Mitchell, Geoffrey K ; van den Akker, Marjan

Objective : To explore the GP's role in providing psychosocial care for cancer survivors through a systematic literature review. Methods : We searched Medline, Embase, PsycINFO, and CINAHL and included studies that complied with the predefined in‐ and exclusion criteria. At least two independent reviewers performed the quality appraisal and data extraction. Results : We included 33 studies (5 qualitative, 19 observational, 9 intervention), the majority of which focussed on care for depression [...]

Menée en Suède à partir de données portant sur 3 865 mères et 3 865 pères de 3 865 enfants atteints d'un cancer diagnostiqué avant l'âge de 18 ans, cette étude analyse l'impact, sur les revenus et sur la situation professionnelle des parents, de la maladie de leur enfant

Socioeconomic consequences of parenting a child with cancer for fathers and mothers in Sweden: A population based difference-in-difference study

Öhman, Mattias ; Woodford, Joanne ; von Essen, Louise

Parents are the primary source of support for children with cancer. To inform clinical practice and health policies the socioeconomic consequences of childhood cancer for fathers and mothers in Sweden were investigated. 3865 mothers and 3865 fathers of 3865 children diagnosed with cancer in Sweden when 0-18 years were followed five years before and ten years after diagnosis. Socioeconomic consequences of the cancer diagnosis on earnings and employment, and mental health (number of inpatient [...]

Menée dans un contexte américain, cette étude compare le rapport coût-efficacité de stratégies thérapeutiques d'entretien chez des patientes atteintes d'un cancer épithélial de l'ovaire, selon la classification moléculaire de la tumeur (présence d'un variant BRCA, défaut de recombinaison homologue sans variant BRCA, maîtrise de la recombinaison homologue)

Cost-effectiveness of Maintenance Therapy Based on Molecular Classification Following Treatment of Primary Epithelial Ovarian Cancer in the United States

Penn, Courtney A. ; Wong, Melissa S. ; Walsh, Christine S.

Importance : There are large randomized clinical trials—SOLO-1 (Olaparib Maintenance Monotherapy in Patients With BRCA Mutated Ovarian Cancer Following First Line Platinum Based Chemotherapy [December 2018]), PRIMA (A Study of Niraparib Maintenance Treatment in Patients With Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy [September 2019]), and PAOLA-1 (Platine, Avastin and Olaparib in 1st Line [December 2019])—reporting positive efficacy results for [...]

Mené aux Etats-Unis sur 144 patientes atteintes d'un cancer du sein, cet essai randomisé évalue l'intérêt d'une intervention multimédia pour améliorer leurs capacités à discuter de leurs difficultés sexuelles

Efficacy of a Multimedia Intervention in Facilitating Breast Cancer Patients’ Clinical Communication about Sexual Health: Results of a Randomized Controlled Trial

Reese, Jennifer Barsky ; Sorice, Kristen A. ; Pollard, Whitney ; Handorf, Elizabeth ; Beach, Mary Catherine ; Daly, Mary B. ; Porter, Laura S. ; Tulsky, James A. ; Lepore, Stephen J.

Objective : Many women with breast cancer hesitate to raise sexual concerns clinically. We evaluated a multimedia intervention to facilitate BC patients’ communication about sexual/menopausal health, called Starting the Conversation (STC). Methods : Female BC patients (N=144) were randomly assigned to either STC [20‐minute video, workbook, and resource guide] or control [resource guide only]. Audio‐recorded dialogue from patients’ next oncology clinic encounter was coded for patients’ sexual [...]