Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
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Sommaire du n° 462 du 25 septembre 2020
Lutte contre les cancers
Qualité de vie, soins de support (2)
A partir d'une revue systématique de la littérature (33 études, 3 962 patients), cette méta-analyse évalue l'intérêt, pour réduire les morbidités postopératoires, d'interventions pré-opératoires (exercices physiques, nutrition, aide psychologique, cessation tabagique, etc.) chez des patients âgés atteints d'un cancer et devant subir un traitement chirurgical abdominal
Prehabilitation in elective abdominal cancer surgery in older patients: systematic review and meta-analysis
A partir d'une revue systématique de la littérature (33 études, 3 962 patients), cette méta-analyse évalue l'intérêt, pour réduire les morbidités postopératoires, d'interventions pré-opératoires (exercices physiques, nutrition, aide psychologique, cessation tabagique, etc.) chez des patients âgés atteints d'un cancer et devant subir un traitement chirurgical abdominal
Prehabilitation in elective abdominal cancer surgery in older patients: systematic review and meta-analysis
Daniels, S. L. ; Lee, M. J. ; George, J. ; Kerr, K. ; Moug, S. ; Wilson, T. R. ; Brown, S. R. ; Wyld, L.
Background : Prehabilitation has emerged as a strategy to prepare patients for elective abdominal cancer surgery with documented improvements in postoperative outcomes. The aim of this study was to assess the evidence for prehabilitation interventions of relevance to the older adult. Methods : Systematic searches were conducted using MEDLINE, Web of Science, Scopus, CINAHL and PsychINFO. Studies of preoperative intervention (prehabilitation) in patients undergoing abdominal cancer surgery [...]
Menée aux Etats-Unis par questionnaire auprès de patients stomisés ayant survécu à un cancer (200 répondants), cette étude transversale analyse l’association entre des comportements de santé sains (alimentation, activité physique) et la qualité de vie
Healthy behaviors are associated with positive outcomes for cancer survivors with ostomies: a cross-sectional study
Menée aux Etats-Unis par questionnaire auprès de patients stomisés ayant survécu à un cancer (200 répondants), cette étude transversale analyse l’association entre des comportements de santé sains (alimentation, activité physique) et la qualité de vie
Healthy behaviors are associated with positive outcomes for cancer survivors with ostomies: a cross-sectional study
Julia Mo, Cynthia A. Thomson, Virginia Sun, Christopher S. Wendel
Background : Cancer survivors (CS) with ostomies may face challenges in sustaining physical activity (PA) levels and maintaining healthy diets. This analysis describes lifestyle behaviors and their relationships with health-related quality of life (HRQOL) in CS with ostomies. Methods : This is a cross-sectional, secondary analysis of a multisite randomized self-management education trial for CS with ostomies. The baseline self-reported measures were queried on aerobic PA and diet using the City [...]
Observation (8)
Menée à partir des données des registres américains des cancers, cette étude présente une estimation de l’incidence des cancers et de la mortalité spécifique chez les adolescents et jeunes adultes (âge : 15-39 ans) pour l’année 2020
Cancer statistics for adolescents and young adults, 2020
Menée à partir des données des registres américains des cancers, cette étude présente une estimation de l’incidence des cancers et de la mortalité spécifique chez les adolescents et jeunes adultes (âge : 15-39 ans) pour l’année 2020
Cancer statistics for adolescents and young adults, 2020
Kimberly D. Miller, Miranda Fidler Benaoudia, Theresa H. Keegan (et al.)
Cancer statistics for adolescents and young adults (AYAs) (aged 15?39 years) are often presented in aggregate, masking important heterogeneity. The authors analyzed population?based cancer incidence and mortality for AYAs in the United States by age group (ages 15?19, 20?29, and 30?39 years), sex, and race/ethnicity. In 2020, there will be approximately 89,500 new cancer cases and 9270 cancer deaths in AYAs. Overall cancer incidence increased in all AYA age groups during the most recent decade [...]
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Determinants of the outcomes of patients with cancer infected with SARS-CoV-2: results from the Gustave Roussy cohort
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Determinants of the outcomes of patients with cancer infected with SARS-CoV-2: results from the Gustave Roussy cohort
Albiges, Laurence ; Foulon, Stéphanie ; Bayle, Arnaud ; Gachot, Bertrand ; Pommeret, Fanny ; Willekens, Christophe ; Stoclin, Annabelle ; Merad, Mansouria ; Griscelli, Frank ; Lacroix, Ludovic ; Netzer, Florence ; Hueso, Thomas ; Balleyguier, Corinne ; Ammari, Samy ; Colomba, Emeline ; Baciarello, Giulia ; Perret, Audrey ; Hollebecque, Antoine ; Hadoux, Julien ; Michot, Jean-Marie ; Chaput, Nathalie ; Saada, Veronique ; Hauchecorne, Mathilde ; Micol, Jean-Baptiste ; Sun, Roger ; Valteau-Couanet, Dominique ; Andre, Fabrice ; Scotté, Florian ; Besse, Benjamin ; Soria, Jean-Charles ; Barlesi, Fabrice
Patients with cancer are presumed to be at increased risk of severe COVID-19 outcomes due to underlying malignancy and treatment-induced immunosuppression. Of the first 178 patients managed for COVID-19 at the Gustave Roussy Cancer Centre, 125 (70.2%) were hospitalized, 47 (26.4%) developed clinical worsening and 31 (17.4%) died. An age of over 70 years, smoking status, metastatic disease, cytotoxic chemotherapy and an Eastern Cooperative Oncology Group score of ≥2 at the last visit were the [...]
Changes in Lung Cancer Treatment as a Result of the Coronavirus Disease 2019 Pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Changes in Lung Cancer Treatment as a Result of the Coronavirus Disease 2019 Pandemic
Arielle Elkrief, Suzanne Kazandjian, Nathaniel Bouganim
Patients with cancer have higher mortality rates from coronavirus disease 2019 (COVID-19),1-4 particularly those with lung cancer.5 Therefore, efforts are ongoing to limit exposure of these patients to the health care system. As a result, the COVID-19 pandemic has changed cancer care provision, but the extent and type of these changes are unknown. The goal of this study was to evaluate the changes in lung cancer treatment during the COVID-19 pandemic.
Awareness and perceptions related to COVID-19 among cancer patients: A survey in oncology department
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Awareness and perceptions related to COVID-19 among cancer patients: A survey in oncology department
Dilek Erdem, Irem Karaman
Introduction : Today, COVID?19 pandemic is still the most critical problem in the global health agenda. Since the awareness of the public in general and particularly awareness of those with comorbidities, such as cancer, determine the rate of mortality, the primary goal of this study was to assess the knowledge, perceptions and attitude of the patients with cancer towards the COVID?19 pandemic. The secondary objective of this study was also to measure the effect of COVID?19 on cancer patients’ [...]
Repurposing Anticancer Drugs for the Management of COVID-19
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Repurposing Anticancer Drugs for the Management of COVID-19
El Bairi, Khalid ; Trapani, Dario ; Petrillo, Angelica ; Le Page, Cécile ; Zbakh, Hanaa ; Daniele, Bruno ; Belbaraka, Rhizlane ; Curigliano, Giuseppe ; Afqir, Said
Since its outbreak in the last December, coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has rapidly spread worldwide at a pandemic proportion, thus regarded as a global public health emergency. The existing therapeutic options for COVID-19 beyond the intensive supportive care are limited, with an undefined or modest efficacy reported so far. Drug repurposing represents an enthusiastic mechanism to use approved drugs outside the scope of their original indication and accelerate the [...]
Utility of COVID-19 Screening in Cancer Patients
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Utility of COVID-19 Screening in Cancer Patients
Lee, Lennard Y. W. ; Hill, Thomas ; Topping, Oliver ; Tilby, Michael ; Baker, Mark ; Greig, Julian ; Isherwood, Lawrence ; Miller, Robert ; Petrenko, Yuriy ; Desai, Ruchi ; Field, Alice ; Kennedy, Bethany ; Khan, Shahbano ; Kountourou, Alexandra ; Ndlovu, Sandisile ; Starkey, Thomas ; Storey, Francesca ; Turner, Lucy ; Vaughan-Williams, William ; Moyler, Surrinder ; Preston, Helen ; Latty, Beverley ; Walker, Sharon ; Henderson, Daniel R. ; Thompson, Joyce ; Jones, Nicola ; Ghafoor, Qamar ; Pascoe, Jenny ; Williams, Sarah ; Middleton, Gary
Cancer patients are at increased risk from COVID-19. A number of guidelines advise screening patients undergoing chemotherapy. We analyzed 1,988 tests in 1,226 patients from April 3, 2020, to June 22, 2020, as part of the UK Birmingham Chemotherapy Cancer COVID-19 cohort. Uptake of screening was 98.2%, with an asymptomatic infection prevalence of 0.6%. We conclude that where the incidence of asymptomatic infection is low and patients can be identified early, screening enables the confidence to [...]
Sarcoma European and Latin American Network (SELNET) Recommendations on Prioritization in Sarcoma Care During the COVID-19 Pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Sarcoma European and Latin American Network (SELNET) Recommendations on Prioritization in Sarcoma Care During the COVID-19 Pandemic
Martin-Broto, Javier ; Hindi, Nadia ; Aguiar Jr, Samuel ; Badilla-González, Ronald ; Castro-Oliden, Victor ; Chacón, Matias ; Correa-Generoso, Raquel ; De Alava, Enrique ; Donati, Davide Maria ; Eriksson, Mikael ; Falla-Jimenez, Martin ; German, Gisela ; Gobo Silva, Maria Leticia ; Gouin, Francois ; Gronchi, Alessandro ; Haro-Varas, Juan Carlos ; Jiménez-Brenes, Natalia ; Kasper, Bernd ; Lopes de Mello, Celso Abdon ; Maki, Robert ; Martínez-Delgado, Paula ; Martínez-Said, Hector ; Martinez-Tlahuel, Jorge Luis ; Morales-Pérez, Jose Manuel ; Muñoz-Casares, Francisco Cristobal ; Nakagawa, Suely A. ; Ortiz-Cruz, Eduardo Jose ; Palmerini, Emanuela ; Patel, Shreyaskumar ; Moura, David S. ; Stacchiotti, Silvia ; Sunyach, Marie Pierre ; Valverde, Claudia M. ; Waisberg, Federico ; Blay, Jean-Yves
Background The COVID-19 outbreak has resulted in collision between patients infected with SARS-CoV-2 and those with cancer on different fronts. Patients with cancer have been impacted by deferral, modification, and even cessation of therapy. Adaptive measures to minimize hospital exposure, following the precautionary principle, have been proposed for cancer care during COVID-19 era. We present here a consensus on prioritizing recommendations across the continuum of sarcoma patient care. [...]
Evidence-based Management of COVID-19 in Cancer Patients – Guideline by the Infectious Diseases Working Party (AGIHO) of the German Society for Hae...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Evidence-based Management of COVID-19 in Cancer Patients – Guideline by the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO)
Nicola Giesen, Rosanne Sprute, Maria Rüthrich (et al.)
Since its first detection in China in late 2019 the novel coronavirus SARS-CoV-2 and the associated infectious disease COVID-19 continue to have a major impact on global health care and clinical practice. Cancer patients, in particular those with haematological malignancies, seem to be at an increased risk for a severe course of infection. Deliberations to avoid or defer potentially immunosuppressive therapies in these patients need to be balanced against the overarching goal of providing [...]
Psychosocial emergency care in times of COVID-19: the Essen University Hospital concept for corona-infected patients, their relatives, and medical...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Psychosocial emergency care in times of COVID-19: the Essen University Hospital concept for corona-infected patients, their relatives, and medical staff
Rentrop, Vanessa ; Schneider, Johanna Sophie ; Bäuerle, Alexander ; Junne, Florian ; Dörrie, Nora ; Skoda, Eva-Maria ; Schedlowski, Manfred ; Mallmann, Bernhard ; Benecke, Anke-Verena ; Kohler, Hannah ; Gerigk, Monja ; Teigelack, Per ; Emler, Tobias ; Scherbaum, Norbert ; Gradl-Dietsch, Gertraud ; Scheer, Karin ; Teufel, Martin
Due to the SARS CoV-2-virus (COVID-19), anxiety, distress, and insecurity occur more frequently. In particular, infected individuals, their relatives, and medical staff face an increased risk of high psychological distress as a result of the ongoing pandemic. Thus, structured psychosocial emergency concepts are needed. The University hospital of Essen has taken up this challenge by creating the PEC concept to reduce psychosocial long-term consequences for infected patients, relatives, and [...]
The Impact of COVID-19 on Clinical Trial Execution at the Dana-Farber Cancer Institute
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
The Impact of COVID-19 on Clinical Trial Execution at the Dana-Farber Cancer Institute
Tolaney, Sara M ; Lydon, Christine A ; Li, Tianyu ; Dai, Jiale ; Standring, Andrea ; Legor, Kristen A ; Caparrotta, Caryn M ; Schenker, Matthew P ; Glazer, Daniel I ; Tayob, Nabihah ; Dubois, Steven G ; Meyerhardt, Jeffrey A ; Taplin, Mary-Ellen ; Johnson, Bruce E
Interventions designed to limit the spread of COVID-19 are having profound effects on the delivery of healthcare, but data showing the impact on oncology clinical trial enrollment, treatment, and monitoring are limited. We prospectively tracked relevant data from oncology clinical trials at Dana-Farber Cancer Institute (DFCI) from January 1, 2018 to June 30, 2020, including the number of open trials, new patient enrollments, in-person and virtual patient visits, dispensed investigational [...]
Clinical management of lung cancer patients during the outbreak of COVID-19 epidemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Clinical management of lung cancer patients during the outbreak of COVID-19 epidemic
Wang, Li ; Jiang, Man ; Qu, Jialin ; Zhou, Na ; Zhang, Xiaochun
The rapid growth of 2019 novel coronavirus (COVID-19) outbreak in Wuhan, China, at the early December 2019. COVID-19 spread all over the word just a few months. The outbreak of COVID-19 infection poses major threat to international health and economy. World Health Organization (WHO) announced that the new coronavirus was an international public health emergency on January 30, 2020. However, with the spread of COVID-19, the routine medical care of lung cancer patients was affected. Because lung [...]
SARS-CoV-2 Viral Load Predicts Mortality in Patients with and Without Cancer Who Are Hospitalized with COVID-19
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
SARS-CoV-2 Viral Load Predicts Mortality in Patients with and Without Cancer Who Are Hospitalized with COVID-19
Westblade, Lars F. ; Brar, Gagandeep ; Pinheiro, Laura C. ; Paidoussis, Demetrios ; Rajan, Mangala ; Martin, Peter ; Goyal, Parag ; Sepulveda, Jorge L. ; Zhang, Lisa ; George, Gary ; Liu, Dakai ; Whittier, Susan ; Plate, Markus ; Small, Catherine B. ; Rand, Jacob H. ; Cushing, Melissa M. ; Walsh, Thomas J. ; Cooke, Joseph ; Safford, Monika M. ; Loda, Massimo ; Satlin, Michael J.
Patients with cancer may be at increased risk of severe coronavirus disease 2019 (COVID-19), but the role of viral load on this risk is unknown. We measured SARS-CoV-2 viral load using cycle threshold (CT) values from reverse transcription-polymerase chain reaction assays applied to nasopharyngeal swab specimens in 100 patients with cancer and 2914 without cancer who were admitted to three New York City hospitals. Overall, the in-hospital mortality rate was 38.8% among patients with a high [...]
Menée aux Etats-Unis à partir de données portant sur 20 007 patients atteints d’un lymphome hodgkinien classique diagnostiqué entre l’âge de 20 et 74 ans sur la période 2000-2016, cette étude de cohorte analyse les causes de décès en lien avec la chimiothérapie (3 380 décès)
Cause-Specific Mortality Following Initial Chemotherapy in a Population-Based Cohort of Patients With Classical Hodgkin Lymphoma, 2000-2016
Menée aux Etats-Unis à partir de données portant sur 20 007 patients atteints d’un lymphome hodgkinien classique diagnostiqué entre l’âge de 20 et 74 ans sur la période 2000-2016, cette étude de cohorte analyse les causes de décès en lien avec la chimiothérapie (3 380 décès)
Cause-Specific Mortality Following Initial Chemotherapy in a Population-Based Cohort of Patients With Classical Hodgkin Lymphoma, 2000-2016
Graça M. Dores, Rochelle E. Curtis, Nicole H. Dalal, Martha S. Linet (et al.)
PURPOSE : Mortality for patients with classical Hodgkin lymphoma (cHL) treated during an era characterized in the United States by widespread use of doxorubicin, bleomycin, vinblastine, and dacarbazine and diminishing use of radiotherapy is not well understood. PATIENTS AND METHODS : We identified 20,007 individuals diagnosed with stage I/II (early) or III/IV (advanced) cHL between age 20 and 74 years treated with initial chemotherapy in US population-based cancer registries during 2000-2015 [...]
Menée aux Etats-Unis sur la période 1985-2014 auprès de 922 672 participants (durée de suivi : 10 ans), cette étude analyse, en fonction du statut tabagique, l'association entre l'indice de masse corporelle et la mortalité due au cancer du pancréas (7 904 décès)
A Large Cohort Study of Body Mass Index and Pancreatic Cancer by Smoking Status
Menée aux Etats-Unis sur la période 1985-2014 auprès de 922 672 participants (durée de suivi : 10 ans), cette étude analyse, en fonction du statut tabagique, l'association entre l'indice de masse corporelle et la mortalité due au cancer du pancréas (7 904 décès)
A Large Cohort Study of Body Mass Index and Pancreatic Cancer by Smoking Status
Jacobs, Eric J ; Newton, Christina C. ; Stevens, Victoria L. ; Patel, Alpa V. ; Flanders, W. Dana ; Gapstur, Susan M.
Background: Some evidence suggests the association between BMI and pancreatic cancer risk is weaker among current smokers than among never smokers. Methods: We examined the association between BMI and pancreatic cancer mortality among adults who reported smoking status at enrollment into Cancer Prevention Study-II in 1982, including 420,543 never smokers, 282,244 former cigarette smokers, and 219,885 current cigarette smokers. After excluding the first three years of follow-up to reduce [...]
Menée au Japon à partir de données portant sur 16 509 patients atteints d’un cancer du poumon non à petites cellules ayant subi une résection complète (âge médian : 69 ans), cette étude analyse l’association entre l’indice de masse corporelle avant le traitement chirurgical, la survie globale et la survie sans maladie
Impact of the preoperative body mass index on the postoperative outcomes in patients with completely resected non-small cell lung cancer: A retrosp...
Menée au Japon à partir de données portant sur 16 509 patients atteints d’un cancer du poumon non à petites cellules ayant subi une résection complète (âge médian : 69 ans), cette étude analyse l’association entre l’indice de masse corporelle avant le traitement chirurgical, la survie globale et la survie sans maladie
Impact of the preoperative body mass index on the postoperative outcomes in patients with completely resected non-small cell lung cancer: A retrospective analysis of 16,503 cases in a Japanese Lung Cancer Registry Study
Koichi Fukumoto, Shoichi Mori, Yasushi Shintani (et al.)
Objectives : The aim of this study was to evaluate the impact of the preoperative body mass index (BMI) on the postoperative outcomes in patients with completely resected non-small cell lung cancer (NSCLC). Materials and methods : The data of patients with NSCLC in whom R0 resection was achieved were extracted from the database of NSCLC samples accumulated by the Japanese Joint Committee of Lung Cancer Registry in the year 2010, and the surgical outcomes including postoperative morbidity, [...]
Menée aux Etats-Unis à partir de données portant sur 1 171 patients atteints d’un cancer colorectal de stade avancé ou métastatique (âge médian : 59 ans), cette étude de cohorte prospective analyse l’association entre une consommation de café, la survie sans progression et la survie globale (durée médiane de suivi : 5,4 ans)
Association of Coffee Intake With Survival in Patients With Advanced or Metastatic Colorectal Cancer
Menée aux Etats-Unis à partir de données portant sur 1 171 patients atteints d’un cancer colorectal de stade avancé ou métastatique (âge médian : 59 ans), cette étude de cohorte prospective analyse l’association entre une consommation de café, la survie sans progression et la survie globale (durée médiane de suivi : 5,4 ans)
Association of Coffee Intake With Survival in Patients With Advanced or Metastatic Colorectal Cancer
Christopher Mackintosh, Chen Yuan, Fang-Shu Ou (et al.)
Importance : Several compounds found in coffee possess antioxidant, anti-inflammatory, and insulin-sensitizing effects, which may contribute to anticancer activity. Epidemiological studies have identified associations between increased coffee consumption and decreased recurrence and mortality of colorectal cancer. The association between coffee consumption and survival in patients with advanced or metastatic colorectal cancer is unknown. Objective : To evaluate the association of coffee [...]
Coffee and Colorectal Cancer : Is Improved Survival a “Perk” of Coffee Drinking?
Menée aux Etats-Unis à partir de données portant sur 1 171 patients atteints d’un cancer colorectal de stade avancé ou métastatique (âge médian : 59 ans), cette étude de cohorte prospective analyse l’association entre une consommation de café, la survie sans progression et la survie globale (durée médiane de suivi : 5,4 ans)
Coffee and Colorectal Cancer : Is Improved Survival a “Perk” of Coffee Drinking?
Erikka Loftfield, Marc J. Gunter, Rashmi Sinha
Coffee occupies a unique space in nutrition and health research. First, it is widely consumed globally; in the United States, for example, 3 of 4 adults report drinking coffee,1 making it potentially important for public health. Second, coffee drinking is often a daily, and likely a long-term, habit, making it potentially important for individual health. Because coffee is consumed regularly, it is likely captured with relatively little measurement error by self-report1; consequently, studies of [...]
Menée à partir des données des registres américains des cancers portant sur 144 524 femmes atteintes d'un carcinome canalaire in situ diagnostiqué entre 1995 et 2014 (âge moyen au diagnostic : 57,4 ans ; durée de suivi : 1 326 075 personnes-années) et à partir de données en population générale, cette étude évalue l'association entre le diagnostic de la maladie et le risque de décès par cancer du sein
Association of a Diagnosis of Ductal Carcinoma In Situ With Death From Breast Cancer
Menée à partir des données des registres américains des cancers portant sur 144 524 femmes atteintes d'un carcinome canalaire in situ diagnostiqué entre 1995 et 2014 (âge moyen au diagnostic : 57,4 ans ; durée de suivi : 1 326 075 personnes-années) et à partir de données en population générale, cette étude évalue l'association entre le diagnostic de la maladie et le risque de décès par cancer du sein
Association of a Diagnosis of Ductal Carcinoma In Situ With Death From Breast Cancer
Giannakeas, Vasily ; Sopik, Victoria ; Narod, Steven A.
Importance : It is not clear to what extent a diagnosis of ductal carcinoma in situ (DCIS) impacts a woman’s lifetime risk of dying of breast cancer. Under ideal circumstances, treatment will eliminate the risk of invasive ipsilateral recurrence and prevent subsequent mortality from breast cancer. The risk of dying of breast cancer after a diagnosis of DCIS had not been compared with that of women without cancer in the general population. Objective : To determine the risk of death from breast [...]
Menée au Canada par enquête auprès de 333 patients atteints d’un cancer de la tête et du cou (318 répondants), cette étude analyse leurs symptômes auto-déclarés pendant la radiothérapie
Patient-reported outcome measures in patients undergoing radiotherapy for head and neck cancer
Menée au Canada par enquête auprès de 333 patients atteints d’un cancer de la tête et du cou (318 répondants), cette étude analyse leurs symptômes auto-déclarés pendant la radiothérapie
Patient-reported outcome measures in patients undergoing radiotherapy for head and neck cancer
Sarah Nicole Hamilton, Eric Tran, Cheryl Ho, Eric Berthelet, Jonn Wu (et al.)
Objectives : Head and neck (H&N) cancer patients experience significant acute side effects from treatment. This study evaluates prospectively collected patient-reported outcomes (PROs) in H&N patients undergoing radiotherapy (RT) to assess feasibility of electronically collecting PROs and to objectively document symptom acuity and trajectory during RT. Materials and methods : H&N patients undergoing radical RT at our multicentre institution completed a 12-item partial survey of the Vanderbilt [...]
Approches psycho-sociales (5)
Menée aux Etats-Unis à partir de données portant sur 3 096 adultes ayant survécu à un cancer pendant l'enfance et sur 429 témoins, cette étude analyse les facteurs associés à des idées suicidaires sévères et le taux de suicide
Suicidality among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort Study
Menée aux Etats-Unis à partir de données portant sur 3 096 adultes ayant survécu à un cancer pendant l'enfance et sur 429 témoins, cette étude analyse les facteurs associés à des idées suicidaires sévères et le taux de suicide
Suicidality among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort Study
Lubas, Margaret M. ; Mirzaei Salehabadi, Sedigheh ; Lavecchia, Jeanette ; Alberts, Nicole M. ; Krull, Kevin R. ; Ehrhardt, Matthew J. ; Srivastava, Deokumar ; Robison, Leslie L. ; Hudson, Melissa M. ; Brinkman, Tara M.
Background : Suicide is a serious public health concern. An increased risk of suicide ideation previously has been reported among survivors of childhood cancer. Methods : Suicide mortality was assessed for all potentially eligible survivors (those aged ≥18 years who were ≥5 years after their cancer diagnosis; 7312 survivors). Risk factors for acute suicidal ideation were assessed among clinically evaluated survivors (3096 survivors) and the prevalence of acute ideation was compared with that of [...]
A partir d'une revue systématique de la littérature (15 études), cette méta-analyse évalue l'impact, sur l'état psychique et sur la prise en charge médicale des patients, des résultats de tests multigéniques ou de séquençage génomique à signification incertaine
Clinical and psychological outcomes of receiving a variant of uncertain significance from multigene panel testing or genomic sequencing: a systemat...
A partir d'une revue systématique de la littérature (15 études), cette méta-analyse évalue l'impact, sur l'état psychique et sur la prise en charge médicale des patients, des résultats de tests multigéniques ou de séquençage génomique à signification incertaine
Clinical and psychological outcomes of receiving a variant of uncertain significance from multigene panel testing or genomic sequencing: a systematic review and meta-analysis
Mighton, Chloe ; Shickh, Salma ; Uleryk, Elizabeth ; Pechlivanoglou, Petros ; Bombard, Yvonne
This study systematically reviewed and synthesized the literature on psychological and clinical outcomes of receiving a variant of uncertain significance (VUS) from multigene panel testing or genomic sequencing. MEDLINE and EMBASE were searched. Two reviewers screened studies and extracted data. Data were synthesized through meta-analysis and meta-aggregation. The search identified 4539 unique studies and 15 were included in the review. Patients with VUS reported higher genetic test–specific [...]
A partir d’une revue systématique de la littérature (31 études, 7 114 patients), cette méta-analyse identifie les facteurs associés à une stigmatisation chez des patients atteints d’un cancer
Correlates of stigma for patients with cancer: a systematic review and meta-analysis
A partir d’une revue systématique de la littérature (31 études, 7 114 patients), cette méta-analyse identifie les facteurs associés à une stigmatisation chez des patients atteints d’un cancer
Correlates of stigma for patients with cancer: a systematic review and meta-analysis
Zehao Huang, Ting Yu, Siyu Wu & Ailing Hu (et al.)
Objective : The systematic review and meta-analysis was performed to summarize the available evidence and identify the correlates of cancer stigma. Methods : PubMed, EMBASE, Web of Science, the Cochrane Library, and PsycINFO were electronically searched to identify eligible studies about correlates of stigma for patients with cancer. Two reviewers independently screened the literature, extracted data, and assessed the risk of bias of included studies. A meta-analysis was performed using the [...]
Menée en Chine par enquête auprès de 127 patients atteints d’un myélome multiple, cette étude analyse les facteurs, notamment familiaux et sociaux, associés à leur peur de la récidive de la maladie
Fear of Cancer Recurrence in Patients with Multiple Myeloma: Prevalence and Predictors Based on a Family Model Analysis
Menée en Chine par enquête auprès de 127 patients atteints d’un myélome multiple, cette étude analyse les facteurs, notamment familiaux et sociaux, associés à leur peur de la récidive de la maladie
Fear of Cancer Recurrence in Patients with Multiple Myeloma: Prevalence and Predictors Based on a Family Model Analysis
Xiaochun Hu, Weida Wang, Ye Wang, Ke Liu (et al.)
Objective : Fear of cancer recurrence (FCR) is a common psychosocial sequela among cancer survivors, but data on patients with multiple myeloma are scarce. This study calculated the prevalence of FCR and identified family and social factors that predict FCR in the study population. Methods : We recruited 127 myeloma patients and their partners to participate in a cross?sectional survey from a regional tertiary cancer centre in China. The questionnaires included items on demographic [...]
Menée en Chine par questionnaire auprès de 240 patientes atteintes d'un cancer du sein ou d'une maladie bénigne du sein et de 120 témoins, cette étude analyse l'association entre le cancer, le stress et des symptômes de dépression et d'anxiété
Perceived stress, anxiety, and depression in treatment-naïve women with breast cancer: a case-control study
Menée en Chine par questionnaire auprès de 240 patientes atteintes d'un cancer du sein ou d'une maladie bénigne du sein et de 120 témoins, cette étude analyse l'association entre le cancer, le stress et des symptômes de dépression et d'anxiété
Perceived stress, anxiety, and depression in treatment-naïve women with breast cancer: a case-control study
Li, Jie ; Gao, Wei ; Yang, Qianqian ; Cao, Fenglin
Objective : Women with breast cancer face elevated risk for psychological problems. We aimed to examine to what extent treatment-naïve women with breast cancer are at higher risk for perceived stress and symptoms of anxiety and depression, compared with matched women with benign breast disease and healthy women, and explore the contribution of perceived stress in the association between breast cancer and symptoms of anxiety and depression. Methods : The study included 360 women (120 per group). [...]
