Menée au Canada par enquête auprès de 558 jeunes utilisateurs de la cigarette électronique (âge moyen: 18,6 ans ; 53,6 % d'hommes), cette étude analyse, en fonction du sexe, de l'âge et du statut tabagique, leurs perceptions et leurs comportements concernant le vapotage

Perceptions and Experiences of Vaping Among Youth and Young Adult E-Cigarette Users: Considering Age, Gender, and Tobacco Use

Al-Hamdani, Mohammed ; Hopkins, D. Brett ; Hardardottir, Agnes ; Davidson, Myles

Purpose: This study examined differences in the topics of vaping perceptions (positive and negative aspects) and experiences (social media content) among e-cigarette users segmented by age and gender (male and female youth and young adults) and tobacco use (never, former, or current user). Method: E-cigarette users (N = 558, 53.6% male, mean age: 18.6 years [SD = 2.2], mean use: 5.3 days/week [SD = 2.3]) residing in Nova Scotia, Canada, responded to three open-ended topic questions concerning [...]

Cette étude japonaise passe en revue les preuves concernant l'association entre une consommation de produit à base de soja et le risque de maladies chroniques comme le cancer

Soy intake and chronic disease risk: findings from prospective cohort studies in Japan

Nagata, Chisato

There has been much interest in the potential role of soy in reducing the risk of chronic diseases. Soy foods are uniquely rich in isoflavones, a fact that has triggered much research including intervention studies. However, there have been few long-term prospective observational studies that include disease itself as an outcome. High intake of soy foods is intrinsic to the Japanese diet, which can be advantageous for conducting such studies in Japan. The present report reviews the findings [...]

Menée à l'aide de données 2004-2013 de l'assurance maladie coréenne portant sur plus d'1,7 million de personnes, cette étude analyse l'association entre l'utilisation d'aspirine, de metformine ou de statines et l'incidence du cancer gastrique (26 093 cas) ainsi que la mortalité associée (12 456 décès)

Association of aspirin, metformin, and statin use with gastric cancer incidence and mortality: A nationwide cohort study

Cho, Mi Hee ; Yoo, Tae Gon ; Jeong, Su-Min ; Shin, Dong Wook

Anticancer effects of aspirin, metformin, and statins against gastric cancer, one of the most common cancers in the world, have been reported. This retrospective cohort study aimed to investigate independent associations of aspirin, metformin, and statin use with gastric cancer incidence and mortality after adjustment for concomitant use of other drugs, using pooled cohort data extracted from the Korean National Health Insurance claim database. Follow-up started on January 1, 2004 and ended at [...]

Mené sur 171 patients atteints de polypose adénomateuse familiale, cet essai randomisé évalue l'efficacité, du point de vue de la progression de la maladie, et la toxicité d'un traitement combinant éflornithine et sulindac par rapport à un traitement utilisant l'une ou l'autre molécule

Eflornithine plus Sulindac for Prevention of Progression in Familial Adenomatous Polyposis

Burke, Carol A. ; Dekker, Evelien ; Lynch, Patrick ; Samadder, N. Jewel ; Balaguer, Francesc ; Hüneburg, Robert ; Burn, John ; Castells, Antoni ; Gallinger, steven ; Lim, Ramona ; Stoffel, Elena M. ; Gupta, Samir ; Henderson, Alex ; Kallenberg, Frank G. ; Kanth, Priyanka ; Roos, Victorine H. ; Ginsberg, Gregory G. ; Sinicrope, Frank A. ; Strassburg, Christian P. ; Van Cutsem, Eric ; Church, James ; Lalloo, Fiona ; Willingham, Field F. ; Wise, Paul E. ; Grady, William M. ; Ford, Molly ; Weiss, Jennifer M. ; Gryfe, Robert ; Rustgi, Anil K. ; Syngal, Sapna ; Cohen, Alfred

BACKGROUND: The efficacy and safety of combination therapy with eflornithine and sulindac, as compared with either drug alone, in delaying disease progression in patients with familial adenomatous polyposis are unknown. METHODS: We evaluated the efficacy and safety of the combination of eflornithine and sulindac, as compared with either drug alone, in adults with familial adenomatous polyposis. The patients were stratified on the basis of anatomical site with the highest polyp burden and [...]

Menée aux Etats-Unis à partir de données de santé 2003-2017 portant sur près de 8 millions d'enfants bénéficiant d'une assurance maladie, cette étude analyse l'évolution de la vaccination contre le papillomavirus humain (1 ou 2 doses) pendant la décennie qui suit la mise en place de recommandations pour le vaccin anti-HPV chez les filles et les garçons

Trends in Human Papillomavirus Vaccination in Commercially Insured Children in the United States

Chen, Szu-Ta ; Huybrechts, Krista F. ; Bateman, Brian T. ; Hernández-Díaz, Sonia

OBJECTIVES: The human papillomavirus (HPV) vaccine was recommended in 2006 for girls and in 2011 for boys. The Healthy People 2020 goal for 2-dose HPV vaccination coverage is 80% by age 15 for girls and boys. We used nationwide population-based data to describe trends in HPV vaccination in children. METHODS: We conducted a cohort study nested within the MarketScan health care database between January 2003 and December 2017. Children were followed from the year they turned 9 until HPV [...]

Menée au Canada par enquêtes auprès de 215 216 adultes âgés d'au moins 19 ans, cette étude analyse l'effet, sur les comportements de vapotage et de tabagisme, des lois interdisant l'utilisation de la cigarette électronique dans les lieux publics et les lieux de travail

Changes in adults’ vaping and smoking behaviours associated with aerosol-free laws

Nguyen, Hai V ; Bornstein, Stephen

Objectives: Banning e-cigarette use in public places has attracted considerable debate, with governments adopting different policies. However, little is known about the outcomes of such bans. We investigated the association of banning e-cigarette use in public places and workplaces in Canadian provinces with adults’ vaping and smoking behaviours. Design: Difference-in-differences. Setting: Nationally representative Canadian Tobacco Use Monitoring Survey (CTUMS) and Canadian Tobacco, Alcohol and [...]