A partir d’une revue systématique de la littérature (16 études), cette étude analyse l’intérêt des technologies de e-santé pour aider les familles ayant un enfant atteint d’un cancer

The role of Connected Health technologies in supporting families affected by paediatric cancer: A Systematic Review

Emma Delemere, Rebecca Maguire

Objectives : Families impacted by paediatric cancer are met with logistical, financial and psychological impacts, with SARS?CoV?2 creating additional barriers and stressors for these families. Connected health (CH) may facilitate cancer care. The objective of the present study was to systematically review CH for families/informal caregivers affected by paediatric cancer. Methods : Using search terms relating to: (1) paediatric cancer, (2) family/caregivers, and (3) CH, the databases of [...]

A partir d’une revue systématique de la littérature (24 études), cette étude identifie et analyse l’efficacité des interventions à faible coût permettant d’atténuer une mucite buccale induite par la radiothérapie chez des patients atteints d’un cancer de la tête et du cou

A systematic review of interventions to mitigate radiotherapy-induced oral mucositis in head and neck cancer patients

Catrina Davy, Sharron Heathcote

Background : Oral mucositis is a debilitating consequence of radiotherapy in patients with head and neck cancers. Radiation-induced oral mucositis (RIOM) can cause pain and weight loss, reduce quality of life and affect treatment outcomes. Methods : A systematic review was undertaken to identify and examine the efficacy of low-cost interventions to mitigate RIOM and to develop clinical guidelines based on the evidence. Results : The author identified three interventions: benzydamine [...]

Menée à partir des données des registres américains des cancers portant sur 27 602 patientes atteintes d’un cancer épithélial de l’ovaire diagnostiqué entre 2000 et 2016, cette étude analyse les disparités ethniques dans le risque de second cancer gynécologique en lien avec les traitements anticancéreux

Risks of Second Primary Gynecologic Cancers Following Ovarian Cancer Treatment in Asian Ethnic Subgroups in the United States, 2000–2016

Nita H. Mukand, Ashwini Zolekar, Naomi Y. Ko, Gregory S. Calip

Background: The differential occurrence of second primary cancers by race following ovarian cancer is poorly understood. Our objective was to determine the incidence of second primary gynecologic cancers (SPGC) following definitive therapy for ovarian cancer. Specifically, we aimed to determine differences in SPGC incidence by Asian ethnic subgroups. Methods: We identified 27,602 women ages 20 years and older and diagnosed with first primary epithelial ovarian cancer between 2000 and 2016 who [...]

Menée aux Etats-Unis, cette étude analyse les facteurs associés aux disparités ethniques dans le risque de cancer et la survie

Cancer health disparities in racial/ethnic minorities in the United States

Zavala, Valentina A. ; Bracci, Paige M. ; Carethers, John M. ; Carvajal-Carmona, Luis ; Coggins, Nicole B. ; Cruz-Correa, Marcia R. ; Davis, Melissa ; De Smith, Adam J. ; Dutil, Julie ; Figueiredo, Jane C. ; Fox, Rena ; Graves, Kristi D. ; Gomez, Scarlett Lin ; Llera, Andrea ; Neuhausen, Susan L. ; Newman, Lisa ; Nguyen, Tung ; Palmer, Julie R. ; Palmer, Nynikka R. ; Perez-Stable, Eliseo J. ; Piawah, Sorbarikor ; Rodriquez, Erik J. ; Sanabria-Salas, María Carolina ; Schmit, Stephanie L. ; Serrano-Gómez, Silvia J. ; Stern, Mariana C. ; Weitzel, Jeffrey ; Yang, Jun J. ; Zabaleta, Jovanny ; Ziv, Elad ; Fejerman, Laura

There are well-established disparities in cancer incidence and outcomes by race/ethnicity that result from the interplay between structural, socioeconomic, socio-environmental, behavioural and biological factors. However, large research studies designed to investigate factors contributing to cancer aetiology and progression have mainly focused on populations of European origin. The limitations in clinicopathological and genetic data, as well as the reduced availability of biospecimens from [...]

Menée aux Etats-Unis à partir de données portant sur 1 207 patients ayant survécu à une leucémie lymphoblastique aiguë (âge moyen : 30,6 ans) et sur 2 273 témoins, cette étude analyse l’association entre la chimiothérapie, l’état des fonctions physiques et la présence de déficiences neurocognitives selon le sexe

Sex-specific associations between chemotherapy, chronic conditions and neurocognitive impairment in ALL survivors: A report from the Childhood Cancer Survivor Study

Ellen van der Plas, Weiyu Qiu, Brian J Nieman, Yutaka Yasui (et al.)

Background : The purpose was to examine associations between treatment and chronic health conditions with neurocognitive impairment survivors of acute lymphoblastic leukemia (ALL) treated with chemotherapy only. Methods : This cross-sectional study included 1,207 ALL survivors (54.0% female; mean age 30.6 years) and 2,273 siblings (56.9% female; mean age 47.6 years), who completed the CCSS Neurocognitive Questionnaire. Multivariable logistic regression compared prevalence of neurocognitive [...]

Menée aux Etats-Unis à partir de données portant sur 8 259 adolescents et jeunes adultes ayant survécu au moins 2 ans à un mélanome cutané diagnostiqué entre 1996 et 2012 (âge : 15-39 ans), cette étude analyse les facteurs, notamment ethniques et socioéconomiques, associés à la survenue d’effets indésirables tardifs liés aux traitements anticancéreux

Disparities in the Occurrence of Late Effects Following Treatment among Adolescent and Young Adult Melanoma Survivors

Alicia A. Gingrich, Candice A.M. Sauder, Melanie Goldfarb (et al.)

Background: Melanoma is the third most common cancer in the adolescent and young adult (AYA) population; however, no studies have addressed the occurrence of adverse health conditions following melanoma treatment in these survivors. Methods: Data for patients ages 15 to 39 years diagnosed with cutaneous melanoma from 1996 to 2012 and surviving ?2 years were obtained from the California Cancer Registry and linked to statewide hospitalization data. The influence of age at diagnosis, sex, [...]

Menée en Norvège à partir de données portant sur 244 hommes atteints d’un adénocarcinome de l’œsophage, cette étude analyse l’association entre le niveau d’hormones sexuelles mesuré avant le diagnostic et la survie

Pre-diagnostic Circulating Levels of Sex Hormones and Survival in Esophageal Adenocarcinoma

Shao Hua Xie, Eivind Ness Jensen, Hilde Langseth (et al.)

Sex hormonal differences may contribute to the strong male predominance in esophageal adenocarcinoma (EAC), but whether sex hormone levels influence survival in EAC is unstudied. This study aimed to assess associations between pre?diagnostic sex hormone levels and survival in EAC. In population?based cohort study, 244 male EAC patients from the Janus Serum Bank Cohort in Norway were followed up through 2018. Associations between pre?diagnostic serum levels of 12 sex hormone measures and [...]

Menée aux Etats-Unis à partir de données portant sur 526 690 patients atteints d'un cancer de la prostate traité par prostatectomie radicale entre 2004 et 2014, cette étude analyse les disparités ethniques dans la survie globale et la mortalité

Racial disparities in mortality for patients with prostate cancer after radical prostatectomy

Wen, Wanqing ; Luckenbaugh, Amy N. ; Bayley, Christina E. ; Pension, David F. ; Shu, Xiao-Ou

Background : Although racial disparities in prostate cancer survival are well documented, the relative importance of contributing factors remains unclear. Few studies have examined the disparity between Whites and Hispanics or between Whites and Asian Americans and Pacific Islanders (AAPIs). Methods : Using data from the National Cancer Database for 526,690 patients with prostate cancer who underwent radical prostatectomy between 2004 and 2014, this study systematically evaluated the impact of [...]

Menée aux Etats-Unis à partir de données portant sur 329 adultes ayant survécu à une tumeur cérébrale pendant l’enfance, cette étude analyse la présence de troubles de l'équilibre et les déficiences physiques associées

Balance impairment in survivors of pediatric brain cancers: risk factors and associated physical limitations

Mitra Varedi, Lu Lu, Nicholas S. Phillips (et al.)

Purpose : The study aims were to determine the prevalence of balance impairments in adult survivors of pediatric central nervous system (CNS) tumors, and to identify predictors of and limitations associated with balance impairments. Methods : Participants were adult survivors (N?=?329) of pediatric CNS tumors. Balance was considered impaired among those with composite scores

A partir d’une revue systématique de la littérature publiée de 1994 à 2020 (16 études), cette étude fait le point sur les difficultés psychologiques des patients atteints d’un cancer, défigurés par la maladie et stigmatisés

Stigma in the face of cancer disfigurement: A systematic review and research agenda

Lisa M. Reynolds, Lauren Harris

Introduction : An emerging body of work has reported on the psychological impact of disfigurement on cancer patients; however, the extent of research focusing on stigmatisation in this context is unclear. This review aimed to evaluate how stigma associated with disfigurement impacts on cancer patients. Methods : A systematic review of literature was conducted using SCOPUS, Web of Science, MEDLINE and PubMed databases. Articles were included if they described a qualitative or quantitative study [...]

Menée en France dans la région Rhône-Alpes à partir de données portant sur 271 patientes atteintes d’un cancer épithélial de l’ovaire, cette étude analyse l’effet, sur l’organisation des soins dans le contexte des traitements de première ligne, d’une prise en charge par un comité de concertation pluridisciplinaire

Impact of multidisciplinary tumour board in the management of ovarian carcinoma in the first-line setting. Exhaustive analysis from the Rhone-Alpes region

Domenico Ferraioli, Olivia Bally, Pierre Meeus, David Benayoun (et al.)

Objective : Epithelial ovarian cancer (EOC) is a poor prognosis disease partly linked to diagnosis at an advanced stage. The quality of care management is a factor that needs to be explored, more specifically optimal organisation of first?line treatment. Methods : A retrospective study, dealing with all patients diagnosed within the Rhone?Alpes region with initial diagnosis EOC in 2012, was performed. The aim was to describe the impact of multidisciplinary tumour boards (MTB) in the [...]

Menée aux Etats-Unis par enquête auprès de patientes atteintes d'un cancer du sein diagnostiqué entre 18 et 39 ans (830 répondantes), cette étude analyse l'impact des coûts liés aux traitements sur l'accès aux soins

Treatment cost and access to care: experiences of young women diagnosed with breast cancer

Subramanian, Sujha ; Tangka, Florence K. L. ; Edwards, Patrick ; Jones, Madeleine ; Flanigan, Tim ; Kaganova, Jenya ; Smith, Kevin ; Thomas, Cheryll C. ; Hawkins, Nikki A. ; Rodriguez, Juan L. ; Guy, Gery P. ; Fairley, Temeika

Purpose : Breast cancer is the leading cause of cancer-related deaths in women younger than 40 years. We aim to evaluate cost as a barrier to care among female breast cancer patients diagnosed between 18 to 39 years. Methods : In early 2017, we distributed a survey to women diagnosed with breast cancer between the ages of 18 and 39 years, as identified by the central cancer registries of California, Georgia, North Carolina, and Florida. We used multivariable statistics to explore cost-related [...]