A partir d'une revue de la littérature, cette étude analyse l'association entre une consommation d'algues marines et l'incidence des cancers, la mortalité associée ou des facteurs de risque de maladies chroniques (diabète, hypertension...)

Impact of seaweed intake on health

Murai, Utako ; Yamagishi, Kazumasa ; Kishida, Rie ; Iso, Hiroyasu

Seaweeds contain minerals, vitamins, soluble dietary fibers, and flavonoids, which are regarded as preventive agents against lifestyle-related diseases. Seaweeds are consumed commonly in East Asian countries including Japan. Thus, intake of seaweeds might contribute to Japanese longevity via prevention of lifestyle-related diseases. Recently, two large Japanese cohort studies have reported the association of seaweed intake with reduced risk of cardiovascular diseases. On the other hand, [...]

Menée au Japon par questionnaire auprès de 42 788 femmes et 36 860 hommes (âge : 45-74 ans), cette étude analyse l'association entre une consommation de produits à base de soja fermenté et le risque de cancer, en fonction du sexe

Fermented soy products intake and risk of cardiovascular disease and total cancer incidence: The Japan Public Health Center-based Prospective study

Nozue, Miho ; Shimazu, Taichi ; Charvat, Hadrien ; Mori, Nagisa ; Mutoh, Michihiro ; Sawada, Norie ; Iwasaki, Motoki ; Yamaji, Taiki ; Inoue, Manami ; Kokubo, Yoshihiro ; Yamagishi, Kazumasa ; Iso, Hiroyasu ; Tsugane, Shoichiro

Background/objectives: The association of fermented soy products, separately from total soy products, with cardiovascular disease (CVD) and total cancer has not been reported. We examined this association in a population-based prospective cohort study in Japan. Subjects/methods: We studied 79,648 participants (42,788 women; 36,860 men) aged 45–74 years without a history of cancer, myocardial infarction, or stroke. Participants completed a food frequency questionnaire (1995–1998) and were [...]

Menée à partir de données des cohortes "the Nurses’ Health Study" et "the Health Professionals Follow-Up Study" portant sur 133 924 individus (durée de suivi : 3 585 019 personnes-années), cette étude analyse l'association entre une consommation de café et l'incidence du cancer colorectal (3 161 cas), en fonction de la densité des lymphocytes T dans les tissus tumoraux

Coffee Intake and Colorectal Cancer Incidence According to T-cell Response

Ugai, Tomotaka ; Haruki, Koichiro ; Väyrynen, Juha P ; Zhong, Rong ; Borowsky, Jennifer ; Fujiyoshi, Kenji ; Lau, Mai Chan ; Zhao, Melissa ; Akimoto, Naohiko ; Chang, Tzuu-Wang ; Kishikawa, Junko ; Arima, Kota ; Shi, Shan-shan ; Gu, Simeng ; Fuchs, Charles S ; Giovannucci, Edward L ; Giannakis, Marios ; Zhang, Xuehong ; Song, Mingyang ; Meyerhardt, Jeffrey A ; Wang, Molin ; Nowak, Jonathan A ; Ogino, Shuji

We hypothesized that the associations between coffee intake and colorectal cancer (CRC) incidence might differ by immune cell densities in CRC tissue. Utilizing the Nurses’ Health Study and the Health Professionals Follow-up Study, we examined the association of coffee intake with incidence of CRC classified by intraepithelial or stromal T-cell subset densities by multiplex immunofluorescence assay for CD3, CD4, CD8, CD45RO (PTPRC), and FOXP3. We applied inverse probability weighted Cox [...]

A partir d'une revue systématique de la littérature publiée jusqu'en septembre 2019 (34 études, 403 196 patients), cette méta-analyse évalue l'association entre une utilisation de biphosphonates et le risque de cancer

Bisphosphonates and risk of cancers: a systematic review and meta-analysis

Li, Yuan-Yuan ; Gao, Li-Jie ; Zhang, Yu-Xue ; Liu, Shu-Juan ; Cheng, Shuo ; Liu, Yu-Peng ; Jia, Cun-Xian

Background: It is unclear whether bisphosphonates are associated with risk of cancers. Therefore, this meta-analysis aimed to evaluate the effect of bisphosphonates on overall cancers. Methods: A search in Pubmed, Embase, Cochrane Library and Web of Science databases was conducted, from the inception date of each resource to September 26, 2019. The summarised effect estimates with 95% CIs were calculated using a random-effect model. Heterogeneity and publication bias were explored. Results: [...]

Menée en Iran entre 2016 et 2019 auprès de 3 065 témoins et de 633 patients atteints d'un cancer de la tête et du cou, cette étude multicentrique analyse l'association entre l'usage d'opium (fréquence et quantité) et le risque de développer la maladie, en fonction du statut tabagique

Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma

Mohebbi, Elham ; Hadji, Maryam ; Rashidian, Hamideh ; Rezaianzadeh, Abass ; Marzban, Maryam ; Haghdoost, Ali Akbar ; Tahami, Ahmad Naghibzadeh ; Moradi, Abdolvahab ; Gholipour, Mahin ; Najafi, Farid ; Safari-Faramani, Roya ; Alizadeh-Navaei, Reza ; Ansari-Moghaddam, Alireza ; Bakhshi, Mahdieh ; Nejatizadeh, Azim ; Mahmoudi, Masumeh ; Shahidsales, Soodabeh ; Ahmadi-Simab, Saeideh ; Mianroodi, Ali Asghar Arabi ; Seyyedsalehi, Monireh Sadat ; Hosseini, Bayan ; Peyghambari, Vahideh ; Shirkhoda, Mohammad ; Shirkoohi, Reza ; Ebrahimi, Elmira ; Manifar, Soheila ; Mohagheghi, Mohammad Ali ; Rozek, Laura ; Brennan, Paul ; Poustchi, Hossein ; Etemadi, Arash ; Pukkala, Eero ; Schüz, Joachim ; Malekzadeh, Reza ; Weiderpass, Elisabete ; Rahimi-Movaghar, Afarin ; Boffetta, Paolo ; Kamanagar, Farin ; Zendehdel, Kazem

Scant evidence exists to support the association of opium use with head and neck cancer, limited to the larynx and oral cavity. In a multicenter case-control study -Iran Opium and Cancer study (IROPICAN), we recruited 633 cases of head and neck squamous cell carcinoma (HNSCC) (254 lip and oral cavity, 54 pharynx, 327 larynx, and 28 other sub-sites within the head and neck) and 3065 frequency-matched controls from April 2016 to April 2019. Odds ratios (ORs) for opium use and 95% confidence [...]

Menée à l'aide d'une méthode de randomisation mendélienne et de données de la "UK Biobank" portant sur 367 586 personnes, puis répliquée à partir de données portant sur 121 579 personnes supplémentaires, cette étude analyse l'association entre la durée du sommeil et le risque de cancer, en général et pour 22 localisations spécifiques

Sleep duration and risk of overall and 22 site-specific cancers: a Mendelian randomization study

Titova, Olga E ; Michaelsson, Karl ; Vithayathil, Mathew ; Mason, Amy M ; Kar, Siddhartha ; Burgess, Stephen ; Larsson, Susanna C

Studies of sleep duration in relation to the risk of site-specific cancers other than breast cancer are scarce. Furthermore, the available results are inconclusive and the causality remains unclear. We aimed to investigate the potential causal associations of sleep duration with overall and site-specific cancers using the Mendelian randomization (MR) design. Single-nucleotide polymorphisms associated with the sleep traits identified from a genome-wide association study were used as instrumental [...]

Menée aux Etats-Unis auprès de 183 filles suivies entre 6 et 14 ans, cette étude identifie différents facteurs pouvant influer sur l'association entre l'âge lors des premières règles et le risque de cancer du sein

Pubertal Growth, IGF-1, and Windows of Susceptibility: Puberty and Future Breast Cancer Risk

Biro, Frank M. ; Huang, Bin ; Wasserman, Halley ; Gordon, Catherine M. ; Pinney, Susan M.

Purpose: Risk markers for breast cancer include earlier onset of menarche (age at menarche [AAM]) and peak height velocity (PHV). Insulin-like growth factor-1 (IGF-1) is associated with pubertal milestones, as well as cancer risk. This study examined the relationships between pubertal milestones associated with breast cancer risk and hormone changes in puberty. Methods: This is a longitudinal study of pubertal maturation in 183 girls, recruited at ages 6–7, followed up between 2004 and 2018. [...]