Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
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Pour retrouver les publications signalées par Nota Bene Cancer (archives indexées à partir du n°127 du 1" mars 2012) :
Sommaire du n° 459 du 4 septembre 2020
Lutte contre les cancers
Qualité de vie, soins de support (5)
A partir d’une revue systématique de la littérature publiée entre 2009 et 2019 (15 études), cette étude analyse la prévalence des troubles liés à la nutrition (mucite buccale, nausées et vomissements, diarrhée, dysgueusie) chez des patients atteints d’un cancer et recevant une greffe de cellules souches hématopoïétiques, et identifie les interventions non pharmacologiques pour les prendre en charge
Nutritional problems and their non-pharmacological treatment in adults undergoing haematopoietic stem cell transplantation—A systematic review
A partir d’une revue systématique de la littérature publiée entre 2009 et 2019 (15 études), cette étude analyse la prévalence des troubles liés à la nutrition (mucite buccale, nausées et vomissements, diarrhée, dysgueusie) chez des patients atteints d’un cancer et recevant une greffe de cellules souches hématopoïétiques, et identifie les interventions non pharmacologiques pour les prendre en charge
Nutritional problems and their non-pharmacological treatment in adults undergoing haematopoietic stem cell transplantation—A systematic review
Doris Eglseer, Carola Seymann, Christa Lohrmann, Manuela Hoedl
Objective : This systematic review aimed to identify the most relevant problems related to malnutrition in adult patients undergoing haematopoietic stem cell transplantation (HSCT) and to identify non?pharmacological interventions to treat these problems. Methods : A systematic search for each research question was performed in MEDLINE, CINAHL, Embase, the Cochrane Library, Google Scholar and reference lists in the period 2009–2019. Results : Six and nine studies were included respectively. [...]
Menée en France par questionnaire auprès de 89 patients atteints d’un cancer, cette étude analyse la sévérité des altérations du goût et de l’odorat induites par la chimiothérapie et l’impact de ces altérations sur leurs comportements alimentaires auto-déclarés
Chemotherapy-induced taste and smell changes influence food perception in cancer patients
Menée en France par questionnaire auprès de 89 patients atteints d’un cancer, cette étude analyse la sévérité des altérations du goût et de l’odorat induites par la chimiothérapie et l’impact de ces altérations sur leurs comportements alimentaires auto-déclarés
Chemotherapy-induced taste and smell changes influence food perception in cancer patients
K. Drareni, M. Bensafi, A. Giboreau, A. Dougkas
Purpose : Chemotherapy-induced taste and smell alterations may have a negative impact on the quality of life and nutritional status. A prominent issue when dealing with taste and smell alterations and their consequences on food behavior and well-being lies in the variation arising from individual differences in chemosensory perceptions. The main aim of this study was to examine the effect of individuals’ variation in the severity of taste and smell alterations relative to the stage of [...]
Menée en Allemagne par questionnaire auprès de 2 508 patients atteints d’un cancer, cette étude analyse leurs connaissances et leurs perceptions relatives à la fatigue liée à la maladie ainsi que leur façon de la prendre en charge
Knowledge, perceptions, and management of cancer-related fatigue: the patients' perspective
Menée en Allemagne par questionnaire auprès de 2 508 patients atteints d’un cancer, cette étude analyse leurs connaissances et leurs perceptions relatives à la fatigue liée à la maladie ainsi que leur façon de la prendre en charge
Knowledge, perceptions, and management of cancer-related fatigue: the patients' perspective
Martina E. Schmidt, Susanne Bergbold, Silke Hermann & Karen Steindorf (et al.)
Purpose : This study aimed to assess cancer patients’ knowledge and perceptions regarding fatigue and to provide up-to-date information on the current fatigue management from the patients’ perspective. Methods : The FiX study recruited 2508 cancer patients approximately 2 years after diagnosis via a cancer registry in Germany. Participants completed a questionnaire on their knowledge and perceptions of fatigue and the management received. Results : More than half of respondents (58%), [...]
Menée aux Etats-Unis à partir de données portant sur 3 901 patients ayant reçu un traitement chirurgical (hystérectomie ou chirurgie du côlon ou du rectum) pour un cancer ou une autre pathologie, cette étude analyse les facteurs associés à une utilisation prolongée d’opioïdes
Risk of persistent opioid use following major surgery in matched samples of patients with and without cancer
Menée aux Etats-Unis à partir de données portant sur 3 901 patients ayant reçu un traitement chirurgical (hystérectomie ou chirurgie du côlon ou du rectum) pour un cancer ou une autre pathologie, cette étude analyse les facteurs associés à une utilisation prolongée d’opioïdes
Risk of persistent opioid use following major surgery in matched samples of patients with and without cancer
Mary Falcone, Chongliang Luo, Yong Chen, David Birtwell, Martin Cheatle (et al.)
Background: The opioid crisis has reached epidemic proportions, yet risk of persistent opioid use following curative intent surgery for cancer and factors influencing this risk are not well understood. Methods: We used electronic health record data from 3,901 adult patients who received a prescription for an opioid analgesic related to hysterectomy or large bowel surgery from January 1st, 2013 through June 30th, 2018. Patients with and without a cancer diagnosis were matched based on [...]
Mené sur 20 patients atteints d’un carcinome à cellules rénales de stade métastatique, cet essai randomisé évalue l’efficacité, du point de vue de l’arrêt de la diarrhée 4 semaines après la fin des traitements anticancéreux, d’une transplantation de microbiote fécal pour traiter une diarrhée induite par les inhibiteurs de tyrosine kinase
Faecal microbiota transplantation for the treatment of diarrhoea induced by tyrosine-kinase inhibitors in patients with metastatic renal cell carci...
Mené sur 20 patients atteints d’un carcinome à cellules rénales de stade métastatique, cet essai randomisé évalue l’efficacité, du point de vue de l’arrêt de la diarrhée 4 semaines après la fin des traitements anticancéreux, d’une transplantation de microbiote fécal pour traiter une diarrhée induite par les inhibiteurs de tyrosine kinase
Faecal microbiota transplantation for the treatment of diarrhoea induced by tyrosine-kinase inhibitors in patients with metastatic renal cell carcinoma
Gianluca Ianiro, Ernesto Rossi, Andrew M. Thomas (et al.)
Diarrhoea is one of the most burdensome and common adverse events of chemotherapeutics, and has no standardised therapy to date. Increasing evidence suggests that the gut microbiome can influence the development of chemotherapy-induced diarrhoea. Here we report findings from a randomised clinical trial of faecal microbiota transplantation (FMT) to treat diarrhoea induced by tyrosine kinase inhibitors (TKI) in patients with metastatic renal cell carcinoma (ClinicalTrials.gov number: [...]
Observation (2)
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Colorectal cancer referrals during the COVID-19 pandemic - a model for the faster diagnosis standard?
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Colorectal cancer referrals during the COVID-19 pandemic - a model for the faster diagnosis standard?
Barrett, K. ; Habib Bedwani, N. ; Arya, S. ; Bhargava, A.
The COVID‐19 pandemic forced an unprecedented shift in the organisation of NHS cancer services, with a simultaneous reduction observed in the capacity to investigate individuals with suspected colo‐rectal cancer (CRC) through the two week wait (2WW) pathway1. Like many UK units, our trust restructured its cancer pathways to better utilise diagnostic services and safely investigate patients suspected of CRC2. A consultant‐led telephone triage service was implemented to assess suitability of [...]
Prioritisation by FIT to mitigate the impact of delays in the 2-week wait colorectal cancer referral pathway during the COVID-19 pandemic: a UK mod...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Prioritisation by FIT to mitigate the impact of delays in the 2-week wait colorectal cancer referral pathway during the COVID-19 pandemic: a UK modelling study
Chey Loveday, Amit Sud, Michael E Jones (et al.)
Objective : To evaluate the impact of faecal immunochemical testing (FIT) prioritisation to mitigate the impact of delays in the colorectal cancer (CRC) urgent diagnostic (2-week-wait (2WW)) pathway consequent from the COVID-19 pandemic. Design : We modelled the reduction in CRC survival and life years lost resultant from per-patient delays of 2–6 months in the 2WW pathway. We stratified by age group, individual-level benefit in CRC survival versus age-specific nosocomial COVID-19–related [...]
The impact of the COVID-19 pandemic on colorectal cancer service provision
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
The impact of the COVID-19 pandemic on colorectal cancer service provision
Christos Kontovounisios, CRC COVID Research Collaborative
Over 42 000 colorectal cancer (CRC) cases are diagnosed in the UK each year. Multiple hospital and patient factors are involved in the safe functioning of colorectal cancer (CRC) services, most of which the COVID?19 pandemic has impacted. The literature so far has sought to predict the potential disruption in surgical and cancer care during the pandemic. We have evaluated the degree of adherence and deviation from the best practice guidelines and to describe the modifications to the colorectal [...]
Prevalence of Surface Contamination With SARS-CoV-2 in a Radiation Oncology Clinic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Prevalence of Surface Contamination With SARS-CoV-2 in a Radiation Oncology Clinic
Imraan Jan, Kenneth Chen, Mutlay Sayan (et al.)
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a global pandemic. It is hypothesized that the virus spreads from person to person via respiratory droplets or contact with contaminated surfaces and objects.1,2 Prior studies evaluating environmental contamination with SARS-CoV-2 have been conducted in health care settings treating patients known to have coronavirus disease 2019 (COVID-19)3; however, studies evaluating clinics that do not [...]
Stage migration of colorectal cancer during COVID-19 pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Stage migration of colorectal cancer during COVID-19 pandemic
Liyanage, A. S. D. ; Gokul, K. ; Babu, B. H. ; Ainsworth, P.
All cancer pathways across the UK have been adversely affected by the implications of COVID‐19 pandemic. Colorectal cancer (CRC) pathway by no means an exclusion to this adversity. Treatments of large number of CRC, have been either deferred or revised to minimise the detrimental outcomes of concurrent SARS‐CoV‐2 infection1, 2. Colorectal cancer being largely a disease of advanced age, SARS‐CoV‐2 infections could have deleterious effects in them. Cancer research UK has extrapolated that [...]
Seroprevalence of SARS-CoV-2–specific antibodies in cancer outpatients in Madrid (Spain): A single center, prospective, cohort study and a review o...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Seroprevalence of SARS-CoV-2–specific antibodies in cancer outpatients in Madrid (Spain): A single center, prospective, cohort study and a review of available data
Luis Cabezón-Gutiérrez, Sara Custodio-Cabello, Magda Palka-Kotlowska (et al.)
Background : Coronavirus disease in 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has emerged as a global pandemic. Published data suggests that patients with a history of or active malignancy are at increased risk of infection and developing COVID-19 related complications. To date, the published data has analyzed the seroprevalence of COVID-19 infection in the general population, but not in cancer patients. Here we present the results of prevalence of [...]
Study of the gastrointestinal tumor progression during the COVID-19 epidemic in Wuhan
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Study of the gastrointestinal tumor progression during the COVID-19 epidemic in Wuhan
Ming Cai, Geng Wang, Yuanjue Wu, Zheng Wang, Guobing Wang, Kaixiong Tao (et al.)
Due to the restriction caused by the COVID?19 epidemic, the cancer community currently faces many difficulties1. First, tumor patients had to risk the chances of exposure when they went to the cancer clinic. Second, cancer treatment could predispose patients to more serious effects of COVID?19. Third, infection of COVID?19 after tumor surgeries could lead to higher levels of comorbidity2, 3. Thus, the surgeons and oncologists have to weigh the risk of COVID?19 infection against the magnitude of [...]
Mortality in patients with cancer and COVID-19: A systematic review and pooled analysis of 52 studies
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Mortality in patients with cancer and COVID-19: A systematic review and pooled analysis of 52 studies
Saini, Kamal S. ; Tagliamento, Marco ; Lambertini, Matteo ; McNally, Richard ; Romano, Marco ; Leone, Manuela ; Curigliano, Giuseppe ; de Azambuja, Evandro
Patients with COVID-19 who have underlying malignancy have a higher mortality rate compared with those without cancer, although the magnitude of such excess risk is not clearly defined. We performed a systematic review and pooled analysis to provide precise estimates of the mortality rate among patients with both cancer and COVID-19.
COVID-19 and its impact on endoscopy services: what is the threshold for missed malignant diagnosis?
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
COVID-19 and its impact on endoscopy services: what is the threshold for missed malignant diagnosis?
Tony He, Michael B MacIsaac, Simon J Hume, Alexander J Thompson (et al.)
We read the study by Rutter et al1 with interest. The substantial decrease in the cancer detection rate in the UK as a consequence of a reduction in endoscopy activity during the COVID-19 era is alarming. Early in the lockdown, UK endoscopy activity dropped to as low as 5% of pre-COVID levels, with activity only increasing to 20% after 10 weeks. More selective screening did significantly increase the per-procedure cancer detection rate (pre-COVID 1.91%; COVID-19 impacted 6.61%; p<0.001); [...]
Menée en Allemagne à partir de données portant sur 1 239 enfants nés de patients ayant survécu à un cancer pédiatrique, cette étude analyse leur état de santé à la naissance (naissance avant terme, poids à la naissance, malformations congénitales, etc.) selon le mode de conception (utilisation de technologies de procréation assistée ou grossesse spontanée)
Health outcomes in offspring born to survivors of childhood cancers following assisted reproductive technologies
Menée en Allemagne à partir de données portant sur 1 239 enfants nés de patients ayant survécu à un cancer pédiatrique, cette étude analyse leur état de santé à la naissance (naissance avant terme, poids à la naissance, malformations congénitales, etc.) selon le mode de conception (utilisation de technologies de procréation assistée ou grossesse spontanée)
Health outcomes in offspring born to survivors of childhood cancers following assisted reproductive technologies
Greta Sommerhäuser, Anja Borgmann-Staudt, Kathy Astrahantseff, Katja Baust (et al.)
Purpose : An increasing number of childhood cancer survivors are using assisted reproductive technologies (ART) to overcome treatment-related fertility impairment. We report perinatal and health outcomes of offspring born to survivors following ART. Methods : The FeCt Multicenter Offspring Study surveyed the health of offspring of childhood cancer survivors. Health outcomes in offspring born to survivors following ART (n?=?57, 4.6%) or after spontaneous conception (n?=?1182) were assessed in [...]
Approches psycho-sociales (1)
A partir d’une revue systématique de la littérature publiée entre 2013 et 2018 (7 études), cette étude française fait le point sur les traitements de la dépression chez les patients âgés atteints d’un cancer
Dealing with the lack of evidence to treat depression in older patients with cancer: French Societies of Geriatric Oncology (SOFOG) and PsychoOncol...
A partir d’une revue systématique de la littérature publiée entre 2013 et 2018 (7 études), cette étude française fait le point sur les traitements de la dépression chez les patients âgés atteints d’un cancer
Dealing with the lack of evidence to treat depression in older patients with cancer: French Societies of Geriatric Oncology (SOFOG) and PsychoOncology (SFFPO) position paper based on a systematic review
Bérengère Beauplet, Ophélie Soulie, Jean-Yves Niemier, Cécile Pons-Peyneau (et al.)
Introduction : Depression symptoms, frequently diagnosed in older patients with cancer, impacts on oncological treatment feasibility. The Francophone Society of Geriatric Oncology (SOFOG) has initiated a systematic review on depression treatment in older patients with cancer, to advocate guidelines. Data sources : Medline via PubMed, Embase, CENTRAL. Methods : We included randomized and non-randomized controlled trials, reviews and meta-analysis, retrospective and prospective cohort studies, [...]
