Menée aux Etats-Unis à partir des données 2007-2014 de la base Medicare portant sur 69 889 patients ayant survécu à un cancer (sein, côlon-rectum, prostate) diagnostiqué entre 66 et 89 ans, et sur 125 007 témoins, cette étude de cohorte rétrospective estime le taux d'overdoses d’opioïdes non fatales et de troubles liés à une utilisation d’opioïdes

Opioid use disorder and overdose in older adults with breast, colorectal, or prostate cancer

Andrew W Roberts, Samantha Eiffert, Elizabeth M Wulff-Burchfield (et al.)

Background : Despite high rates of opioid therapy, evidence about the risk of preventable opioid harms among cancer survivors is underdeveloped. Our objective was to estimate the odds of opioid use disorder (OUD) and overdose following breast, colorectal, or prostate cancer diagnosis among Medicare beneficiaries. Methods : We conducted a retrospective cohort study using 2007-2014 SEER-Medicare data for cancer survivors with a first cancer diagnosis of stage 0-III breast, colorectal, or prostate [...]

Menée à partir de données portant sur 1 208 adultes ayant survécu à un cancer pédiatrique, cette étude analyse l’évolution de la douleur en lien avec leur utilisation d’opioïdes et de marijuana

Change in Pain Status and Subsequent Opioid and Marijuana Use Among Long-Term Adult Survivors of Childhood Cancer

I-Chan Huang, Nicole M Alberts, Merrion G Buckley (et al.)

We evaluated pain status change and associations with subsequent opioid/marijuana use among 1,208 adult survivors of childhood cancer. Pain status and opioid/marijuana were self-reported at baseline and follow-up evaluation (mean interval: 4.2 years). Over time, 18.7% of survivors endorsed persistent/increasing significant pain; 4.8% and 9.0% reported having used opioids and marijuana at follow-up. Persistent/increased (vs. none/decreased) pain, persistent/increased (vs. none/decreased) [...]

A partir d’une revue systématique de la littérature publiée jusqu’en septembre 2019 (14 articles), cette étude analyse l’efficacité des interventions nutritionnelles (comportant une supplémentation orale et/ou des conseils nutritionnels) pour améliorer le poids et l’apport énergétique chez des patients atteints d’un cancer gastrique, colorectal, œsophagien ou pancréatique, avant et après un traitement chirurgical

Oral nutrition interventions in patients undergoing gastrointestinal surgery for cancer: A systematic literature review

Lauren Reece, Sophie Hogan, Margaret Allman-Farinelli & Sharon Carey

Purpose : Weight loss and poor food intake have been shown to affect several outcomes in patients undergoing surgery for gastrointestinal cancer. This review aims to examine the effect of pre-, post- or perioperative nutrition interventions focused on increasing oral energy or protein intake in patients undergoing surgery for gastrointestinal cancer. Interventions using standard oral nutrition supplements and/or dietary counselling were included. The primary outcome was weight change, and [...]

Mené sur 81 patients atteints d’un cancer (âge médian :55 ans), cet essai de phase II évalue l’efficacité du cannabis thérapeutique dispensé par voie orale pour prévenir les nausées et vomissement induits par une chimiothérapie

Oral THC:CBD cannabis extract for refractory chemotherapy-induced nausea and vomiting (CINV): a randomised, placebo-controlled, phase 2 crossover trial

P.Grimison, A.Mersiades, A.Kirby, N.Lintzeris (et al.)

Background : This multi-centre, randomised, double-blinded, placebo-controlled, phase 2/3 trial is aimed to evaluate an oral THC:CBD cannabis extract for prevention of refractory CINV. Here we report the phase 2 component results. Patients and methods : Eligible patients experienced CINV during moderate-highly emetogenic intravenous chemotherapy despite guideline-consistent anti-emetic prophylaxis. Study treatment consisted of 1 cycle of 1-4 self-titrated capsules oral THC 2.5mg/CBD 2.5mg [...]

Menée aux Etats-Unis par enquêtes 2, 5 et 8 ans après le diagnostic auprès de 633 aidants familiaux de patients atteints d’un cancer, cette étude prospective analyse l’évolution de leurs besoins en soins de support pour réduire leur détresse psychologique et améliorer leur qualité de vie

Passages of cancer caregivers' unmet needs across 8 years

Youngmee Kim, Charles S. Carver, Amanda Ting (et al.)

Background : Identifying and addressing caregivers' unmet needs have been suggested as a way of reducing their distress and improving their quality of life. However, the needs of family cancer caregivers are complex in the period of long?term survivorship in particular because they may diverge as the patients' survivorship trajectory does, and that is what this study investigated. Methods : Family cancer caregivers completed prospective, longitudinal surveys 2, 5, and 8 years after diagnosis (n [...]

A partir d’une revue systématique de la littérature (17 études, 867 femmes et 2 hommes), cette étude analyse l’efficacité d’un drainage lymphatique manuel pour soulager un lymphœdème associé à un cancer du sein

Manual lymphatic drainage treatment for lymphedema: a systematic review of the literature

Belinda Thompson, Katrina Gaitatzis, Xanne Janse de Jonge (et al.)

Purpose : Manual lymphatic drainage (MLD) massage is widely accepted as a conservative treatment for lymphedema. This systematic review aims to examine the methodologies used in recent research and evaluate the effectiveness of MLD for those at-risk of or living with lymphedema. Methods : The electronic databases Embase, PubMed, CINAHL Complete and Cochrane Central Register of Controlled Trials were searched using relevant terms. Studies comparing MLD with another intervention or control in [...]

Menée aux Pays-Bas par entretiens auprès de 26 patientes atteintes d’un cancer du sein, cette étude qualitative analyse l’impact des cicatrices après un traitement chirurgical sur leur qualité de vie

The impact of scars on health-related quality of life after breast surgery: a qualitative exploration

Kristel E. Everaars, Marlies Welbie, Stefan Hummelink, Esther P. M. Tjin (et al.)

Purpose : The purpose of this research was to explore women’s experiences after breast surgery with scar characteristics and symptoms, and its impact on their health-related quality of life (HRQOL). Material and methods : A qualitative study using semi-structured face-to-face interviews was conducted among women following prophylactic, oncologic, or reconstructive breast surgery in the Netherlands. A directed content analysis was performed using guiding themes. Themes were “physical and sensory [...]

Menée à l'aide de données portant sur 369 patients fumeurs atteints d'un cancer diagnostiqué entre 2013 et 2015 (59% d'hommes ; durée médiane de suivi : 15 mois), cette étude analyse l'effet, sur la survie, d'un sevrage tabagique dans les 6 mois suivant le diagnostic de la maladie

Smoking cessation and survival among people diagnosed with non-metastatic cancer

Barnett, Tracey E. ; Lu, Yan ; Gehr, Aaron W. ; Ghabach, Bassam ; Ojha, Rohit P.

Background: We aimed to estimate the effects of smoking cessation on survival among people diagnosed with cancer. Methods: We used data from a Comprehensive Community Cancer Program that is part of a large urban safety-net hospital system. Eligible patients were diagnosed with primary invasive solid tumors between 2013 and 2015, and were current smokers at time of diagnosis. Our exposure of interest was initiation of smoking cessation within 6 months of cancer diagnosis. We estimated inverse [...]

Menée aux Etats-Unis par enquête auprès de 497 patients ayant survécu à un cancer colorectal ou mammaire diagnostiqué entre 1999 et 2009 (156 répondants ; âge moyen lors du diagnostic : 50 ans), cette étude analyse leurs comportements de santé, notamment le recours au dépistage, l’utilisation des soins et des services de suivi et de prévention de la récidive de la maladie

Cancer surveillance and preventive services in a diverse sample of breast and colorectal cancer survivors

Beth A. Glenn, Narissa J. Nonzee, Ann S. Hamilton (et al.)

Purpose : Cancer survivors diagnosed at an early age remain at risk for cancer recurrence and other chronic diseases. This study assessed engagement in surveillance for recurrence, cancer screening, and other recommended preventive health services among breast and colorectal cancer survivors with early-onset disease (??50 years) who were diagnosed in California. Methods : Breast and colorectal cancer survivors diagnosed with early-onset cancer between 1999 and 2009 were identified through the [...]

Menée aux Etats-Unis à partir de données portant sur 431 patients ayant survécu à une tumeur abdominale ou pelvienne pendant l’enfance, cette étude analyse les changements de la composition corporelle, la santé métabolique et la survenue de déficiences physiques en lien avec la radiothérapie

Body Composition, Metabolic Health, and Functional Impairment among Adults Treated for Abdominal and Pelvic Tumors during Childhood

Carmen L. Wilson, Wei Liu, Wassim Chemaitilly, Carrie R. Howell (et al.)

Background: We aimed to characterize body composition, metabolic impairments, and physical performance among survivors of pediatric abdominal and pelvic solid tumors. Methods: Participants included 431 survivors of abdominal or pelvic tumors [median attained age = 29.9 (range: 18.7–55.1) years]. Relative lean mass and fat mass were assessed with dual X-ray absorptiometry. Metabolic outcomes [insulin resistance (IR), high-density lipoprotein (HDL), low-density lipoprotein, and triglycerides] [...]

Menée en Australie auprès de plus de 2,3 millions de patients atteints d'un cancer diagnostiqué entre 1985 et 2014 (âge : 15-89 ans), cette étude estime, du point de vue de la survie à 10 ans et sur 3 périodes, le nombre de décès par cancer évité grâce à l'amélioration de la prise en charge de la maladie

Quantifying the Number of Cancer Deaths Avoided Due to Improvements in Cancer Survival Since the 1980s in the Australian Population, 1985–2014

Dasgupta, Paramita ; M. Cramb, Susanna ; Kou, Kou ; Yu, Xue Qin ; Baade, Peter D.

Background: This study quantifies the number of potentially “avoided”cancer deaths due to differences in 10-year relative survival between three time periods, reflecting temporal improvements in cancer diagnostic and/or treatment practices in Australia. Methods: National population-based cohort of 2,307,565 Australians ages 15 to 89 years, diagnosed with a primary invasive cancer from 1985 to 2014 with mortality follow-up to December 31, 2015. Excess mortality rates and crude probabilities of [...]

Menée aux Etats-Unis, cette étude analyse l'évolution, sur la période 2001-2017, de l'incidence des cancers associés à une infection par le papillomavirus humain chez les femmes, selon l'appartenance ethnique et l'âge

Incidence trends and burden of human papillomavirus-associated cancers among women in the United States, 2001-2017

Deshmukh, Ashish A ; Suk, Ryan ; Shiels, Meredith S ; Damgacioglu, Haluk ; Lin, Yueh-Yun ; Stier, Elizabeth A ; Nyitray, Alan G ; Chiao, Elizabeth Y ; Nemutlu, Gizem S ; Chhatwal, Jagpreet ; Schmeler, Kathleen ; Sigel, Keith ; Sonawane, Kalyani

Human papillomavirus (HPV) associated anal and oropharyngeal cancer incidence has increased in recent years among US women. However, trends in incidence and burden (annual number of cases) of non-cervical HPV-associated cancers relative to cervical cancer remain unclear. Using the 2001-2017 US cancer statistics dataset, we evaluated contemporary incidence trends and burden (annual number of cases) of HPV-associated cancers among women by anatomic site, race/ethnicity, and age. Overall, cervical [...]

Menée sur la période 1983-2012, cette étude analyse l’évolution de l’incidence de 28 types de cancers au Canada, et souligne notamment l’incidence de la maladie chez les adultes de moins de 50 ans

Emerging cancer incidence trends in Canada: The growing burden of young adult cancers

Emily V. Heer, Andrew S. Harper, Hyuna Sung (et al.)

Background : Recent studies have identified increases in cancer incidence among younger adults for some cancers. This study examined incidence trends for 28 cancers in Canada by age and birth cohort from 1983 to 2012. Methods : Canadian incidence data for 20 to 84 year?olds were obtained from the Cancer Incidence in Five Continents Plus database. Age?period?cohort modeling was used to estimate the average annual percentage changes (AAPCs) and incidence rate ratios (IRRs) for 10?year birth [...]

Menée aux Etats-Unis à partir des données d'une enquête réalisée entre 2006 et 2018 auprès de 381 989 participants (âge moyen : 49 ans ; 55,3 % de femmes), cette étude analyse les tendances de l'arrêt du tabac après un diagnostic de cancer (35 524 cas)

Assessment of Trends in Cigarette Smoking Cessation After Cancer Diagnosis Among US Adults, 2000 to 2017

Talluri, Rajesh ; Fokom Domgue, Joël ; Gritz, Ellen R. ; Shete, Sanjay

Continued cigarette smoking after cancer diagnosis has been shown to adversely alter the cancer survivor’s health outcomes and quality of life. Although considerable progress has been made in reducing cigarette smoking in the United States over the last decades, trends in cigarette smoking cessation among cancer survivors have not yet been fully investigated.To evaluate temporal trends in cigarette smoking cessation and their sociodemographic and behavioral correlates in the US population of [...]

Menée à partir de données européennes sur les décès par cancer du poumon depuis 1950, cette étude estime la part de la mortalité attribuable au tabagisme pour 28 pays jusqu'en 2100, en fonction du sexe

Smoking epidemic in Europe in the 21st century

Janssen, Fanny ; El Gewily, Shady ; Bardoutsos, Anastasios

Objective: To estimate smoking-attributable mortality in the long-term future in 29 European countries using a novel data-driven forecasting approach that integrates the wave pattern of the smoking epidemic and the cohort dimension. Methods: We estimated and forecasted age-specific and age-standardised smoking-attributable mortality fractions (SAMF) and 95% projection intervals for 29 European countries by sex, 1950–2100, using age-period-cohort modelling with a generalised logit link function. [...]

Menée à partir des données 2001-2016 des registres américains des cancers, cette étude analyse l'évolution de l'incidence du cancer du poumon et de la mortalité spécifique ainsi que les effets des avancées thérapeutiques sur cette mortalité

The Effect of Advances in Lung-Cancer Treatment on Population Mortality

Howlader, Nadia ; Forjaz, Gonçalo ; Mooradian, Meghan J. ; Meza, Rafael ; Kong, Chung Yin ; Cronin, Kathleen A. ; Mariotto, Angela B. ; Lowy, Douglas R. ; Feuer, Eric J.

Background : Lung cancer is made up of distinct subtypes, including non–small-cell lung cancer (NSCLC) and small-cell lung cancer (SCLC). Although overall mortality from lung cancer has been declining in the United States, little is known about mortality trends according to cancer subtype at the population level because death certificates do not record subtype information. Methods : Using data from Surveillance, Epidemiology, and End Results (SEER) areas, we assessed lung-cancer mortality and [...]

Menée à partir des données des registres américains des cancers portant sur 716 319 patients ayant survécu 1 an à un cancer de la prostate diagnostiqué sur la période 2000-2015 entre l'âge de 35 et 84 ans, cette étude de cohorte rétrospective analyse les disparités ethniques dans le risque de développer un second cancer

Racial and ethnic differences in risk of second primary cancers among prostate cancer survivors

Withrow, Diana R. ; Schonfeld, Sara J. ; Curtis, Rochelle E. ; Morton, Lindsay M. ; Cook, Michael B. ; Butler, Eboneé N. ; Berrington de Gonzalez, Amy

Purpose : Previous studies have shown an overall decreased risk of second cancers among prostate cancer survivors, but this has not been comprehensively examined by race/ethnicity. We conducted a retrospective cohort study of 716,319 one-year survivors of prostate cancer diagnosed at ages 35–84 during 2000–2015 as reported to 17 US Surveillance, Epidemiology and End Results (SEER) registries. Methods : We estimated standardized incidence ratios (SIRs) for second primary non-prostate [...]

Menée à partir des données des registres américains des cancers portant sur 47 337 patients atteints d’un sarcome sur la période 2001-2015, cette étude analyse les disparités ethniques dans l’association entre le statut socioéconomique, la nature de l’assurance santé (publique ou privée) et la présence de métastases au moment du diagnostic

Associations of Socioeconomic Status, Public vs Private Insurance, and Race/Ethnicity With Metastatic Sarcoma at Diagnosis

Brandon J. Diessner, Brenda J. Weigel, Paari Murugan (et al.)

Importance : Approximately 10% to 30% of patients with sarcoma present with detectable metastases at diagnosis. However, the extent to which presentation with metastases is due to delayed diagnosis vs other factors remains unclear. Objective : To evaluate whether socioeconomic status, insurance status, or race/ethnicity were associated with the presence of metastases at diagnosis of sarcoma. Design, Setting, and Participants : This cross-sectional study used data from the population-based [...]

Menée à partir des données du registre danois des cancers portant sur 1 273 patients pédiatriques nés entre 1981 et 2013 et atteints d’une tumeur du système nerveux central avant l’âge de 19 ans et portant sur 5 086 témoins, cette étude analyse les disparités socioéconomiques dans l’incidence de la maladie

Socioeconomic differences in the risk of childhood central nervous system tumors in Denmark: a nationwide register-based case–control study

Friederike Erdmann, Ulla Arthur Hvidtfeldt, Mette Sørensen (et al.)

Purpose : Differences in the risk of childhood central nervous system (CNS) tumors by socioeconomic status (SES) may enhance etiologic insights. We conducted a nationwide register-based case–control study to evaluate socioeconomic differences in the risk of childhood CNS tumors in Denmark and examined whether associations varied by different SES measures, time points of assessment, specific tumor types, and age at diagnosis. Methods : We identified all children born between 1981 and 2013 and [...]

Menée aux Etats-Unis auprès de 479 patients atteints d'un cancer anaplasique de la thyroïde diagnostiqué entre 2000 et 2019 (âge médian : 65 ans ; 51 % d'hommes), cette étude analyse l'évolution du taux de survie globale au cours des 2 dernières décennies

Evaluation of Overall Survival in Patients With Anaplastic Thyroid Carcinoma, 2000-2019

Maniakas, Anastasios ; Dadu, Ramona ; Busaidy, Naifa L. ; Wang, Jennifer R. ; Ferrarotto, Renata ; Lu, Charles ; Williams, Michelle D. ; Gunn, G. Brandon ; Hofmann, Marie-Claude ; Cote, Gilbert ; Sperling, Jared ; Gross, Neil D. ; Sturgis, Erich M. ; Goepfert, Ryan P. ; Lai, Stephen Y. ; Cabanillas, Maria E. ; Zafereo, Mark

Anaplastic thyroid carcinoma (ATC) historically has a 4-month median overall survival (OS) from time of diagnosis, with disease-specific mortality approaching 100%. The association between recent major advancements in treatment and OS has yet to be evaluated.To evaluate rates of OS in patients with ATC over the last 2 decades.Retrospective cohort study in a single tertiary care institution. Patients with histopathological confirmation of ATC from January 2000 to October 2019 were included and [...]

Menée aux Etats-Unis entre 2009 et 2016 par enquête auprès de 3 241 hommes et 7 093 femmes, cette étude analyse la prévalence d'une infection orale et génitale par le papillomavirus humain et les facteurs associés, en fonction du sexe

Concurrent and Concordant Oral and Genital High-Risk Human Papillomavirus in the U.S.: Results from the National Health and Nutrition Examination Survey

Custer, James ; Patel, Riddhi ; Delclos, George ; DeSantis, Stacia M

Oropharyngeal cancers associated with high-risk human papillomavirus (HR-HPV) infection are increasing in the U.S., especially among men. We evaluated prevalence and predictors of concurrent (genital and oral) and concordant (same-type) HR-HPV infections in U.S.We used National Health and Nutrition Examination Survey from 2009-2016. Predictors were assessed via multivariable logistic regression.Among 10,334 respondents, 172 (2.1%) had concurrent infections [109 (3.5%) men and 63 (0.76%) women]. [...]

A partir des données de 14 essais randomisés incluant un total de 1 091 patientes atteintes d’un cancer du sein et 1 008 patients atteints d’un cancer de la prostate, cette étude analyse l’impact de facteurs cliniques et sociodémographiques sur l’efficacité d’interventions psychosociales pour soulager leur fatigue liée à la maladie

Moderators of The Effect of Psychosocial Interventions on Fatigue in Women With Breast Cancer and Men With Prostate Cancer: Individual Patient Data Meta-Analyses

HJG Abrahams, H Knoop, M Schreurs, NK Aaronson (et al.)

Objective : Psychosocial interventions can reduce cancer?related fatigue effectively. However, it is still unclear if intervention effects differ across subgroups of patients. These meta?analyses aimed at evaluating moderator effects of (1) sociodemographic characteristics, (2) clinical characteristics, (3) baseline levels of fatigue and other symptoms, and (4) intervention?related characteristics on the effect of psychosocial interventions on cancer?related fatigue in patients with [...]

Menée en Allemagne auprès de 197 couples de parents d’enfants ayant survécu à un cancer (âge au moment du diagnostic : 0-17 ans), cette étude analyse l’association entre leur peur de la récidive de la maladie chez leur enfant et leur qualité de vie

Fear of progression in parents of childhood cancer survivors: A Dyadic data analysis

Mona L Peikert, Laura Inhestern, Konstantin A Krauth (et al.)

Objective : Fear of progression (FoP), also referred to as fear of cancer recurrence, is gaining increasing interest in survivorship research as it constitutes a great burden for patients and relatives. However, only little is known about FoP in parents of childhood cancer survivors. The objective of this study was to investigate the impact of FoP on quality of life (QoL) in parental couples. Methods : We analyzed dyadic data of 197 couples parenting childhood cancer survivors (aged 0?17?years [...]

A partir d’une revue de la littérature publiée jusqu’en 2019 (28 essais randomisés, 3 053 patients), cette méta-analyse évalue l’efficacité des interventions psychosociales basées sur le concept de la pleine conscience pour réduire la sévérité de l’anxiété et de la dépression chez des patients adultes atteints d’un cancer

Association of Mindfulness-Based Interventions With Anxiety Severity in Adults With Cancer : A Systematic Review and Meta-analysis

Sapna Oberoi, Jiayu Yang, Roberta L. Woodgate (et al.)

Importance : Mindfulness-based interventions (MBIs), grounded in mindfulness, focus on purposely paying attention to experiences occurring at the present moment without judgment. MBIs are increasingly used by patients with cancer for the reduction of anxiety, but it remains unclear if MBIs reduce anxiety in patients with cancer. Objective : To evaluate the association of MBIs with reductions in the severity of anxiety in patients with cancer. Data Sources : Systematic searches of MEDLINE, [...]

A partir d’une revue systématique de la littérature publiée jusqu’en mai 2020 (46 études, 17 outils), cette étude analyse l’intérêt des outils permettant d’évaluer l’image corporelle et l’estime de soi chez des patients atteints d’un cancer de la prostate

A Systematic Review of Tools Used to Assess Body Image, Masculinity and Self-Esteem in Men With Prostate Cancer

Jessica Bowie, Oliver Brunckhorst, Robert Stewart (et al.)

Objective : Masculinity, body image, and self?esteem are important interlinked factors affecting prostate cancer (PCa) patients' quality of life. The aim of this systematic review was to identify and evaluate all tools measuring these domains in men with PCa. Methods : This review was conducted according to PRISMA guidelines with a priori protocol registered. Pubmed, Embase, Medline and Psychinfo were searched from inception to May 2020. Studies using a predefined tool which measured any body [...]

Menée en Irlande par questionnaire auprès de 2 458 patients ayant survécu à un cancer la prostate, cette étude analyse l’association entre un stress induit par des difficultés financières et la fatigue liée à la maladie

Cumulative financial stress as a potential risk factor for cancer-related fatigue among prostate cancer survivors

Liya Lu, Anna Gavin, Frances J. Drummond & Linda Sharp (et al.)

Introduction : Cancer-related fatigue (CRF) is the most commonly reported treatment-related side effect of prostate cancer (PCa). Recognition of financial hardship among cancer survivors is growing. We investigated, for the first time, associations between levels of financial stress and CRF among PCa survivors. Methods : We used data from PCa survivors who had been identified through two population-based cancer registries covering the Republic of Ireland and Northern Ireland and had completed a [...]

Menée au Canada auprès 1 992 patients atteints d’un cancer de la tête et du cou traité par radiothérapie, cette étude analyse l’association entre une intervention de nature psycho-pédagogique dispensée avant les traitements anticancéreux et la survie globale, la survie sans récidive locorégionale ainsi que la récidive locorégionale

Pre-treatment psychoeducational intervention and outcomes in head and neck cancer patients undergoing radiotherapy

Nauman H. Malik, Manjula Maganti, Maurene McQuestion (et al.)

Background : To investigate the relationship between attendance to a pre-treatment psychoeducational intervention (prehab) with treatment outcomes and toxicities in patients receiving radiotherapy for head and neck cancers (HNCs). Methods : Patients were included from prehab inception in 2013 to 2017, comparing overall survival (OS), locoregional recurrence-free survival (LRFS), and locoregional recurrence (LRR) between prehab attendees (PA) and non-attendees (PNA). Multivariable analysis was [...]

A partir d’une revue systématique de la littérature publiée entre 2008 et 2018 (25 études), cette étude analyse les coûts associés à la prise en charge psycho-sociale des patients atteints d’un cancer

The psychosocial cost burden of cancer: A systematic literature review

Beverley M. Essue, Nicolas Iragorri, Natalie Fitzgerald (et al.)

Background : Psychosocial costs, or quality of life costs, account for psychological distress, pain, suffering and other negative experiences associated with cancer. They contribute to the overall economic burden of cancer that patients experience. But this category of costs remains poorly understood. This hinders opportunities to make the best cancer control policy decisions. This study explored the psychosocial cost burden associated with cancer, how studies measure psychosocial costs and the [...]

Menée dans un contexte américain, cette étude analyse le rapport coût-efficacité des recommandations internationales concernant la prévention de l’insuffisance cardiaque chez des patients ayant survécu à un cancer pédiatrique

Cost-Effectiveness of the International Late Effects of Childhood Cancer Guideline Harmonization Group Screening Guidelines to Prevent Heart Failure in Survivors of Childhood Cancer

Matthew J. Ehrhardt, Zachary J. Ward, Qi Liu (et al.)

PURPOSE : Survivors of childhood cancer treated with anthracyclines and/or chest-directed radiation are at increased risk for heart failure (HF). The International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG) recommends risk-based screening echocardiograms, but evidence supporting its frequency and cost-effectiveness is limited. PATIENTS AND METHODS : Using the Childhood Cancer Survivor Study and St Jude Lifetime Cohort, we developed a microsimulation model of the [...]

Menée dans un contexte néerlandais, cette étude compare le rapport coût-efficacité de diverses stratégies de dépistage du cancer colorectal

Comparing the cost-effectiveness of innovative colorectal cancer screening tests

Elisabeth F P Peterse, Reinier G S Meester, Lucie de Jonge (et al.)

Background : Colorectal cancer (CRC) screening with colonoscopy and the fecal immunochemical test (FIT) is underutilized. Innovative tests could increase screening acceptance. This study determined which of the available alternatives is most promising from a cost-effectiveness perspective. Methods : The previously-validated MISCAN-Colon model was used to evaluate the cost-effectiveness of screening with capsule endoscopy every 5 or 10 years, computed tomographic colonography (CTC) every 5 [...]

Menée dans un contexte néerlandais, cette étude analyse le rapport coût-efficacité d’une stratégie de dépistage du cancer du sein par IRM pour les femmes ayant un risque héréditaire de cancer du sein supérieur ou égal à 20% et sans variant connu des gènes BRCA ou TP3

Cost-effectiveness of Breast Cancer Screening With Magnetic Resonance Imaging for Women at Familial Risk

H. Amarens Geuzinge, Inge-Marie Obdeijn, Emiel J. T. Rutgers (et al.)

Importance : For women with a 20% or more familial risk of breast cancer without a known BRCA1/2 (BRCA1, OMIM 113705; and BRCA2, OMIM 114480) or TP53 (OMIM 151623) variant, screening guidelines vary substantially, and cost-effectiveness analyses are scarce. Objective : To assess the cost-effectiveness of magnetic resonance imaging (MRI) screening strategies for women with a 20% or more familial risk for breast cancer without a known BRCA1/2 or TP53 variant. Design, Setting, and Participants : [...]

Menée au Danemark par questionnaire auprès de 1 475 aidants familiaux de patients décédés d’un cancer, cette étude analyse l’impact, sur leur risque de dépression après le deuil, de discussions avec le médecin concernant le décès du patient en phase terminale

Mortality communication and post-bereavement depression among Danish family caregivers of terminal cancer patients

Yaacov G. Bachner, Mai-Britt Guldin & Mette Kjærgaard Nielsen

Purpose : Depression is the most common negative reaction among family caregivers of terminal cancer patients, persisting to post-bereavement. A modifiable factor associated with depression is mortality communication (i.e., caregiver-relative communication about illness and impending death). The purpose of this study was to examine the impact that mortality communication has on family caregiver’s depression after bereavement, and to translate into Danish and examine the construct validity of [...]

Menée dans 11 pays d’Eurasie par enquête (424 médecins répondants), cette étude analyse leurs perceptions concernant les obstacles à l’intégration précoce des soins palliatifs en oncologie pédiatrique

Barriers to the early integration of palliative care in pediatric oncology in 11 Eurasian countries

Bella S. Ehrlich, Narine Movsisyan, Tsetsegsaikhan Batmunkh (et al.)

Background : The early integration of palliative care significantly improves quality of life for children with cancer. However, cultural, structural, and socioeconomic barriers can delay the integration of palliative care into cancer care, particularly in low?income and middle?income countries. To date, little is known regarding the timing of and barriers to palliative care integration in Eurasia. Methods : The Assessing Doctors' Attitudes on Palliative Treatment (ADAPT) survey evaluates [...]

Menée en Chine par enquête auprès de 419 dyades constituées de patients atteints d’un cancer de stade avancé et de leurs aidants, cette étude transversale analyse les facteurs associés à leurs besoins en soins palliatifs

Prevalence and correlates of unmet palliative care needs in dyads of Chinese patients with advanced cancer and their informal caregivers: a cross-sectional survey

Tao Wang, Alex Molassiotis, Jing-Yu Tan, Betty Pui Man Chung (et al.)

Objectives : To examine palliative care needs of advanced cancer patients and their informal caregivers and correlates of their needs within Chinese context. Methods : This was a cross-sectional survey conducted in two study sites in Mainland China. Patients and caregivers were recruited in dyads. Patients completed the following questionnaires: Problems and Needs in Palliative Care-short version, Hospital Anxiety and Depression Scale (HADS), Edmonton Symptom Assessment Scale (ESAS), Medical [...]

Cet article présente la déclaration de l’«American Society of Clinical Oncology » visant à réduire les inégalités chez les patients atteints d’un cancer et développer des stratégies pour promouvoir l’équité en santé

Cancer Disparities and Health Equity: A Policy Statement From the American Society of Clinical Oncology

Manali I. Patel, Ana Maria Lopez, William Blackstock (et al.)

ASCO strives, through research, education, and promotion of the highest quality of patient care, to create a world where cancer is prevented and every survivor is healthy. In this pursuit, cancer health equity remains the guiding institutional principle that applies to all its activities across the cancer care continuum. In 2009, ASCO committed to addressing differences in cancer outcomes in its original policy statement on cancer disparities. Over the past decade, despite novel diagnostics and [...]