Menée à partir des données de la cohorte européenne EPIC portant sur 323 514 femmes (durée moyenne de suivi : 8,2 ans), cette étude analyse l'association entre un apport en acides gras ou les niveaux d'acides gras circulants et le risque de développer un cancer de l'ovaire (1 486 cas)

Dietary and circulating fatty acids and ovarian cancer risk in the European Prospective Investigation into Cancer and Nutrition

Yammine, Sahar ; Huybrechts, Inge ; Biessy, Carine ; Dossus, Laure ; Aglago, Elom K ; Naudin, Sabine ; Ferrari, Pietro ; Weiderpass, Elisabete ; Tjonneland, Anne ; Hansen, Louise ; Overvad, Kim ; Romana Mancini, Francesca ; Boutron-Ruault, Marie-Christine ; Kvaskoff, Marina ; Fortner, Renée Turzanski ; Kaaks, Rudolf ; Schulze, Matthias B. ; Boing, Heiner ; Trichopoulou, Antonia ; Karakatsani, Anna ; La Vecchia, Carlo ; Benetou, Vassiliki ; Masala, Giovanna ; Krogh, Vittorio ; Mattiello, Amalia ; Macciotta, Alessandra ; Gram, Inger T. ; Skeie, Guri ; Quiros Garcia, Jose Ramon ; Agudo, Antonio ; Sánchez-Pérez, Maria-José ; Chirlaque, María-Dolores ; Ardanaz, Eva ; Gil, Leire ; Sartor, Hanna ; Drake, Isabel ; Idahl, Annika ; Lundin, Eva A ; Aune, Dagfinn ; Ward, Heather A. ; Merritt, Melissa A. ; Allen, Naomi E ; Gunter, Marc J. ; Chajès, Veronique

Background: Fatty acids impact obesity, estrogens and inflammation, risk factors for ovarian cancer. Few epidemiological studies have investigated the association of fatty acids with ovarian cancer. Methods: Within the European Prospective Investigation into Cancer and nutrition, 1,486 incident ovarian cancer cases were identified. Cox Proportional Hazard models with adjustment for ovarian cancer risk factors were used to estimate hazard ratios of ovarian cancer across quintiles of intake of [...]

Menée en 1995 et 2001 par questionnaires auprès de 52 706 femmes afro-américaines (âge : 21-69 ans ; durée moyenne de suivi : 13 ans), cette étude analyse l'association entre une consommation de viandes rouges ou transformées ou de graisses saturées et le risque de cancer du pancréas (168 cas) avant ou après l'âge de 50 ans

A Prospective Analysis of Intake of Red and Processed Meat in Relation to Pancreatic Cancer among African American Women

Petrick, Jessica L. ; Castro-Webb, Nelsy ; Gerlovin, Hanna ; Bethea, Traci N. ; Li, Shanshan ; Ruiz-Narvaez, Edward A ; Rosenberg, Lynn ; Palmer, Julie R.

Background: African Americans have the highest incidence of pancreatic cancer of any racial/ethnic group in the US. There is evidence that consumption of red or processed meat and foods containing saturated fats may increase the risk of pancreatic cancer, but there is limited evidence in African Americans. Methods: Utilizing the Black Women's Health Study (1995-2018), we prospectively investigated the associations of red and processed meat and saturated fats with incidence of pancreatic [...]

Menée en Chine auprès de 59 986 hommes et à l'aide d'une méta-analyse de 28 études de cohorte (durée moyenne de suivi : 9,8 ans), cette étude analyse l'association entre l'apport alimentaire en acides gras et le risque de cancer colorectal (876 cas)

Dietary Fatty Acids and Colorectal Cancer Risk in Men: A Report from the Shanghai Men's Health Study and a Meta-Analysis

Nguyen, Sang ; Li, Honglan ; Yu, Danxia ; Cai, Hui ; Gao, Jing ; Gao, Yutang ; Luu, Hung ; Tran, Huong ; Xiang, Yong-Bing ; Zheng, Wei ; Shu, Xiao-Ou

Evidence from animal models suggests that dietary fatty acids have both anticancer and tumor-promoting effects. Whether dietary fatty acids are associated with colorectal cancer (CRC) in humans remains inconclusive. We investigated associations between dietary fatty acids and risk of CRC among 59,986 men who participated in the Shanghai Men's Health Study (SMHS), an ongoing population-based prospective cohort study. We identified 876 incident CRC cases in the SMHS during a mean follow-up of [...]

A partir d'une revue systématique de la littérature (18 études), cette méta-analyse évalue l'incidence du cancer anal dans les populations à risque avéré, en fonction du sexe

A meta-analysis of anal cancer incidence by risk group: towards a unified anal cancer risk scale

Clifford, Gary M. ; Georges, Damien ; Shiels, Meredith S. ; Engels, Eric A. ; Albuquerque, Andreia ; Poynten, I. Mary ; de Pokomandy, Alexandra ; Easson, Alexandra M. ; Stier, Elizabeth A.

Certain population groups are known to have higher than average anal cancer risk, namely persons living with HIV (PLHIV), men who have sex with men (MSM), women diagnosed with HPV-related gynaecological precancerous lesions or cancer, solid organ transplant recipients (SOTR), and patients with auto-immune diseases. Our aim was to provide robust and comparable estimates of anal cancer burden across these groups. Summary incidence rates (IR), as cases per 100,000 person-years (py), were [...]

Menée aux Pays-Bas, entre 1986 et 2006, par questionnaire auprès de 120 852 participants (âge : 55-69 ans ; durée de suivi : 20,3 ans), cette étude analyse l'hétérogénéité des facteurs de risque (l'indice de masse corporelle, le tabagisme, la consommation d'alcool et l'hypertension) de carcinome à cellules rénales (608 cas)

Etiologic heterogeneity of clear-cell and papillary renal cell carcinoma in the Netherlands Cohort Study

van de Pol, J.A.A. ; George, L. ; van den Brandt, P.A. ; Baldewijns, M.M.L.L. ; Schouten, L.J.

At present, mostly case-control and retrospective studies have investigated the association between etiologic risk factors and the development of histologic subtypes of renal cell carcinoma (RCC). Therefore, we assessed the heterogeneity between body mass index (BMI), cigarette smoking, alcohol consumption and hypertension across clear-cell RCC (ccRCC) and papillary RCC (pRCC) risk in the prospective Netherlands Cohort Study on diet and cancer (NLCS).In 1986, 120,852 participants aged 55-69 [...]