A partir d’une revue de la littérature publiée jusqu’en 2020 (32 articles), cette étude analyse les critères permettant d’évaluer la participation des patients atteints d’un cancer aux activités de la vie quotidienne

Assessments used to measure participation in life activities in individuals with cancer: a scoping review

Allison J. L’Hotta, Taniya E. Varughese, Kathleen D. Lyons (et al.)

Purpose : Individuals with cancer are at high risk for restricted participation in meaningful life activities such as work, school, and social activities. Evaluating participation in life activities is identified as a critical component of rehabilitation referral and triage systems. This scoping review investigates what assessments are used to measure participation in life activities in individuals with cancer. Methods : Six databases were systematically searched using keywords and controlled [...]

Mené en Belgique sur 95 patientes atteintes d’un cancer, cet essai randomisé évalue l’efficacité, pour réduire la fatigue et les symptômes après les traitements anticancéreux, d’une intervention combinant de l’auto-hypnose et des soins auto-appliqués

Effects of an intervention combining self-care and self-hypnosis on fatigue and associated symptoms in post-treatment cancer patients: a randomized-controlled trial

C. Grégoire, M.?E. Faymonville, A. Vanhaudenhuyse (et al.)

Objective : Cancer has a lot of consequences such as fatigue, sleep disturbances, emotional distress, cognitive impairment and reduced physical activity. Some hypnosis?based psychological interventions showed positive effects on fatigue, sleep and emotional distress, but generally focussed on breast cancer patients. Our study aimed at assessing the effects of a group intervention combining self?care and self?hypnosis on quality of life of cancer patients. Methods : Our longitudinal [...]

Mené aux Etats-Unis sur 93 patients ayant survécu à un cancer, cet essai de phase II évalue l’intérêt de deux interventions non pharmacologiques basées sur la psychothérapie comportementale pour traiter leurs troubles du sommeil

A randomized phase II trial evaluating two non-pharmacologic interventions in cancer survivors for the treatment of sleep-wake disturbances: NCCTG N07C4 (Alliance)

Debra L. Barton, Pamela J. Atherton, Daniel V. Satele (et al.)

Purpose : Sleep disturbance is a prevalent problem for cancer survivors and effective behavioral treatments are not widely used for this population. This study evaluated home-based sleep interventions based on cognitive behavioral therapy for insomnia (CBT-I). Methods : This phase II randomized controlled trial evaluated two manualized interventions over 7 weeks. The intervention group received sleep hygiene information, stimulus control, sleep restriction, and a bedtime imagery audio [...]

Menée aux Etats-Unis par enquête en ligne auprès de 80 parents d’un enfant atteint d’un cancer (âge de l’enfant : 2 à 10 ans), cette étude analyse leurs comportements pour faire face aux troubles du sommeil chez l’enfant pendant les traitements

Parental Behaviors, Emotions at Bedtime, and Sleep Disturbances in Children with Cancer

Hyun Kim, Eric S Zhou, Lydia Chevalier (et al.)

Background : Poor sleep is common for children during cancer treatment, but there is limited understanding of the nature of children’s sleep throughout the treatment trajectory. The current exploratory study used an explanatory sequential mixed method approach to examine quantitative associations among sleep problems in children with cancer, parental behavior, and children’s sleep hygiene, with follow-up qualitative characterizations of children’s sleep across cancer treatment stages. Procedure [...]

Mené en Corée sur des patients ayant survécu à un cancer (estomac, côlon, poumon et sein), cet essai randomisé évalue à 12 mois l’intérêt d’un programme en ligne, avec ou sans coaching de santé, pour améliorer leur activité physique, maintenir un poids normal et réduire la détresse psychologique

Efficacy of health coaching and a Web-based program on physical activity, weight, and distress management among cancer survivors: a multi-centered randomised controlled trial

Young Ho Yun, Cheol Il Lim, Eun Sook Lee (et al.)

Objectives : To investigate the efficacy of health coaching and a Web?based program on survivor physical activity (PA), weight, and distress management among stomach, colon, lung and breast cancer patients. Methods : This randomised, controlled, 1?year trial conducted in 5 hospitals recruited cancer survivors within 2 months of completing primary cancer treatment who had not met ?1 of these behavioral goals: i) conducting moderate PA for at least 150 min/week or strenuous exercise for over 75 [...]

Menée en Australie à partir de données portant sur 37 patients atteints d’un cancer de l’œsophage, cette étude rétrospective analyse leur prise en charge nutritionnelle effective tout au long de leur parcours thérapeutique et la compare aux recommandations de bonne pratique

Nutritional management of patients with oesophageal cancer throughout the treatment trajectory: benchmarking against best practice

Merran Findlay, Meredith Purvis, Rosemary Venman (et al.)

Purpose : Oesophageal cancer (OC) impacts nutritional status and outcomes. This study aims to benchmark the current nutrition management of patients with OC against best practice recommendations, identify critical points in the treatment trajectory where nutritional status is compromised, service gaps and opportunities for improvement. Methods : A retrospective audit collected demographic, medical and nutritional data from medical records of patients who received curative treatment for OC at a [...]

A partir d’une revue systématique de la littérature publiée entre 2009 et 2019 (14 études), cette étude analyse les facteurs associés à la qualité de la vie sexuelle chez des patients atteints d’un cancer du côlon

Sexual health in colon cancer patients: a systematic review

Alexandra Stulz, Kristopher Lamore, Lucile Montalescot (et al.)

Objective : Despite the impact that diagnosis and treatment can have on patients’ sexual health, very little research has been conducted on the impact of colon cancer on sexual health. The aim of this systematic review was to assess the prevalence of sexual dysfunctions in colon cancer and describe the sociodemographic, clinical and psychological correlates of sexual dysfunction. Methods : Four electronic databases (PsycINFO, PubMed, AcademicSearchPremier, Cochrane Library) were searched for [...]

Cet article américain discute des enjeux liés à la prise en charge des patients atteints d’un cancer pendant la crise sanitaire liée au COVID-19

Oncology Practice During the COVID-19 Pandemic

Deborah Schrag, Dawn L. Hershman, Ethan Basch (et al.)

In just a few short weeks, the coronavirus disease 2019 (COVID-19) pandemic has transformed health care delivery around the globe. The crisis has dismantled how care is delivered and forced clinicians to make difficult triage decisions about what types and components of care have limited immediate value and which are essential for optimal outcomes. Because some malignancies could pose an immediate threat to survival, cancer provides a lens into the major shifts currently underway in clinical [...]

Cet article croate présente les enjeux liés à la prise en charge des patients atteints d’un cancer pendant la crise sanitaire liée au COVID-19

Cancer and COVID-19; how do we manage cancer optimally through a public health crisis?

Eduard Vrdoljak, Richard Sullivan, Mark Lawler

The outbreak of Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), has thus far infected nearly one million people worldwide, with over 40,000 deaths (1). Epidemiological projections of likely numbers of people who will be infected and die, based on our short experience with this virus, show a significant impact in those above 65 years with comorbidities, but especially in the 80+ group. In an attempt to both reduce COVID-19 [...]

Cet article discute des enjeux liés à la prise en charge des patients atteints d’un cancer pendant la crise sanitaire liée au COVID-19 en Italie

Caring for Patients With Cancer During the COVID-19 Outbreak in Italy

Filippo Pietrantonio, Marina Chiara Garassino

At the time of this writing, the novel coronavirus 2019 (COVID-19) outbreak was detected in Italy only 5 weeks ago, and it has changed our lives and the lives of our families forever. After a 12-hour shift at our hospital, The National Cancer Institute of Milan, we decided to turn off the lights, put a candle near the screens of our laptops, and share our feelings with the oncology community. (…)

Menée au Royaume-Uni, cette étude de cohorte analyse, chez les patients atteints d’un cancer, les facteurs (notamment les traitements anticancéreux) associés à une plus grande vulnérabilité aux infections et aux complications liées au COVID-19, et propose des interventions pour assurer la continuité des soins et limiter les effets du coronavirus pendant la crise sanitaire

Caring for our cancer patients in the wake of COVID-19

Karim Hussien El-Shakankery, Joanna Kefas, Shanthini Mary Crusz

In response to our current global pandemic, unprecedented healthcare changes may have significant consequences for cancer patients in the United Kingdom. We explore why cancer patients may be more susceptible to severe infection and complications, highlighting various interventions that may help to ensure continuity of care in this unique cohort.

Menée à partir des données des registres américains des cancers et de la base Medicare sur la période 1998-2012, cette étude analyse l’évolution des disparités ethniques dans la qualité de vie chez des patients âgés atteints d’un cancer

Trends in Racial/Ethnic Disparity of Health-Related Quality of Life in Older Adults with and without Cancer (1998–2012)

Maria A. Rincon, Ashley Wilder Smith, Mandi Yu (et al.)

Background: Non-White cancer survivors often report poorer health compared with Non-Hispanic Whites. Whether those disparities are changing over time is unknown. We examined changes in health-related quality of life (HRQOL) by race/ethnicity from 1998 to 2012 among older adults with and without cancer. Methods: Data from Medicare Advantage beneficiaries were obtained from the linkage between the Medicare Health Outcomes Survey and Surveillance, Epidemiology, and End Results cancer registry data [...]

Menée à partir des données des registres américains des cancers portant sur 58 356 patients pédiatriques (âge inférieur ou égal à 19 ans) atteints d’un cancer diagnostiqué sur la période 1980-2015, cette étude rétrospective analyse les causes de décès (période de suivi : 45 580 personnes-années ; 6 996 décès dont 5 128 décès par cancer)

Long-term causes of death among pediatric patients with cancer

Samantha R. Horn, Kelsey C. Stoltzfus, Heath B. Mackley (et al.)

Background : The objectives of this study were to characterize the risk of death (1) from the primary cancer vs competing cause of death; and (2) from various causes of death vs the general poplation. The relative risk of death after a pediatric cancer diagnosis versus the general population and the risk of death from a primary cancer diagnosis versus competing causes of death. Methods : This retrospective, population?based study used the Surveillance, Epidemiology, and End Results database [...]

A partir d’une revue systématique de la littérature publiée jusqu’en 2020, cette méta-analyse d’études prospectives (5 études) évalue l’association entre la pratique d’une activité physique de faible intensité objectivement mesurée (exemple : moniteur d'activité physique) et la mortalité par cancer de la prostate

Objectively-Measured Light-Intensity Physical Activity and Risk of Cancer Mortality: A Meta-analysis of Prospective Cohort Studies

Shanhu Qiu, Xue Cai, Tongzhi Wu, Zilin Sun (et al.)

Background: The impact of light-intensity physical activity (LPA) in preventing cancer mortality has been questioned. To address this concern, the present meta-analysis aimed to quantify the association between objectively-measured LPA and risk of cancer mortality.Methods: We conducted a systematic literature search in PubMed and Scopus to January 2020. Prospective cohort studies reporting the association between objectively-measured LPA using activity monitors (e.g., accelerometers) and risk [...]

Cet article discute des enjeux liés à la prise en charge des patients atteints d’un cancer pendant la crise sanitaire liée au COVID-19 au Royaume-Uni

The UK Coronavirus Cancer Monitoring Project: protecting patients with cancer in the era of COVID-19

The UK Coronavirus Cancer Monitoring Project team

The UK Coronavirus Cancer Monitoring Project (UKCCMP) aims to collect, analyse, and disseminate in real time data from the UK cancer centres about severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection rates in patients with cancer, and their outcomes in terms of coronavirus disease 2019 (COVID-19). This approach will enable oncologists to gain crucial insights to inform decision making.In December, 2019, several cases of acute respiratory syndrome in Hubei province, China were [...]

Menée aux Etats-Unis à partir de données portant sur 568 patients atteints d’un mélanome de stade III ou IV traité par immunothérapie entre 2008 et 2019, cette étude analyse l’association entre une utilisation d’antibiotiques antérieure aux traitements anticancéreux (114 cas), la toxicité des immunothérapies et la survie

Association of antibiotic exposure with survival and toxicity in patients with melanoma receiving immunotherapy

Jahan J Mohiuddin, Brian Chu, Andrea Facciabene (et al.)

BACKGROUND : Gut microbial diversity is associated with improved response to immune checkpoint inhibitors (ICI). Based on the known detrimental impact that antibiotics have on microbiome diversity, we hypothesized that antibiotic receipt prior to ICI would be associated with decreased survival. METHODS : Patients with stage III and IV melanoma treated with ICI between 2008 and 2019 were selected from an institutional database. A window of antibiotic receipt within 3 months prior to the first [...]

Menée au Japon sur la période 1993-2014, cette étude analyse l’évolution de l’incidence du cancer de la prostate selon le stade au diagnostic (29 458 cas)

Long-term Trends in Prostate Cancer Incidence by Stage at Diagnosis in Japan Using the Multiple Imputation Approach, 1993–2014

Eiko Saito, Megumi Hori, Tomohiro Matsuda (et al.)

Background: This study aimed to assess long-term trends in the incidence of prostate cancer by stage at diagnosis before and after the introduction of population-based PSA screening. Methods: We used data from three population-based cancer registries in Japan. A total of 29,458 malignant prostate cancer cases diagnosed between 1993 and 2014 were used for the analysis. Multiple imputation with chained equations was used to impute a specific stage at diagnosis for cases with “unknown” and missing [...]

Cette étude présente des projections de la mortalité par cancer en Europe pour l’année 2020, en mettant l’accent sur la mortalité par cancer de la prostate

European cancer mortality predictions for the year 2020 with a focus on prostate cancer

G.Carioli, P.Bertuccio, P.Boffetta (et al.)

Background : Current cancer mortality figures are important for disease management and resource allocation. We estimated mortality counts and rates for 2020 in the European Union (EU) and for its six most populous countries. Materials and methods : We obtained cancer death certification and population data from the World Health Organization and Eurostat databases for 1970–2015. We estimated projections to 2020 for 10 major cancer sites plus all neoplasms and calculated the number of avoided [...]

Menée en Italie par questionnaire auprès de 75 patients ayant survécu 2 ans ou plus à un cancer hématologique, cette étude analyse les facteurs médicaux, socio-démographiques et psychologiques associés à leur peur de la récidive

Fear of cancer recurrence in haematological cancer patients: exploring socio-demographic, psychological, existential and disease-related factors

C. Borreani, S. Alfieri, L. Farina (et al.)

Purpose : This study aims to explore the relation between the dimension of fear of cancer recurrence (FCR) in haematological cancer patients relapse-free for at least 2 years and socio-demographic, related to the disease, psychological and existential factors. Methods : A sample of 75 haematological cancer patients agreed to participate in the study through a self-reported online questionnaire (51.9% males). A total of 70.1% had a low recurrence risk. The questionnaire included [...]

Menée au Canada par questionnaire auprès de 228 patients ayant survécu à un cancer pédiatrique (âge moyen : 14,5 ans ; âge moyen au diagnostic : 4,4 ans), cette étude rétrospective analyse les facteurs associés à leur peur de la récidive

Fear of Cancer Recurrence among Survivors of Childhood Cancer

Hayley Wroot, Arfan Raheen Afzal, Caitlin Forbes (et al.)

Objectives : Fear of Cancer Recurrence (FCR) has not been widely explored in survivors of childhood cancer. Yet, childhood survivors are at risk of experiencing late effects and may be especially vulnerable. The aims of the current study were to conduct a retrospective chart review to determine the prevalence and persistence of FCR among survivors of childhood cancer and to examine factors that may be related to FCR. Methods : Survivors of childhood cancer (n = 228, mean attained age = [...]

A partir d’une revue systématique de la littérature (48 études), cette étude analyse les effets, sur la prise en charge des patients atteints d’un cancer, de la loi sur la protection des patients et les soins abordables ("Obamacare") et de l’expansion de la couverture Medicaid

The Affordable Care Act’s Medicaid Expansion and Impact along the Cancer-Care Continuum: A Systematic Review

Haley A Moss, Jenny Wu, Samantha J Kaplan (et al.)

Background : Health reform and the merits of Medicaid expansion remain at the top of the legislative agenda, with growing evidence suggesting an impact on cancer care and outcomes. A systematic review was undertaken to assess the association between Medicaid expansion and the goals of the ACA in the context of cancer care. The purpose of this paper is to summarize the currently published literature and to determine the effects of Medicaid expansion on outcomes during points along the cancer [...]

Menée en Nouvelle-Zélande, cette étude analyse le rapport coût-efficacité d’un programme de dépistage du cancer du poumon utilisant la tomodensitométrie à faible dose

Cost-effectiveness of a low-dose computed tomography screening programme for lung cancer in New Zealand

Richard Jainea, Giorgi Kvizhinadzea, Nisha Naira (et al.)

Objectives : The cost-effectiveness of low-dose computed tomography (LDCT) screening for lung cancer is uncertain. This study estimated the health gains, costs (net health system, and including ‘unrelated’) and cost-effectiveness of biennial LDCT screening among 55?74 years olds with a smoking history of at least 30 pack years, and (if a former smoker) having quit within last 15 years, in New Zealand. Methods : We used a macrosimulation stage shift model with New Zealand-specific lung cancer [...]

A partir de l’analyse de 394 pages de sites web en langue anglaise, cette étude analyse l’information en ligne concernant l’activité physique et les comportements sédentaires dédiée aux patients ayant survécu à un cancer

Online physical activity and sedentary behaviour information for cancer survivors

Belinda C. Goodwin, Fiona Crawford-Williams, Oscar Castro (et al.)

Purpose : The purpose of this study is to assess the prevalence, content, and nature of information and/or advice regarding physical activity and sedentary behaviour available online for cancer survivors. Methods : A search strategy was designed to identify website links that were most likely to be accessed by cancer survivors, living in five English speaking nations, looking for information about maintaining and improving health after a cancer diagnosis. All content pertaining to physical [...]

Menée à Taïwan, cette étude longitudinale analyse l’intérêt d’une consultation en soins palliatifs pour aider et soulager les aidants familiaux de patients atteints d’un cancer en phase terminale

Effectiveness of palliative care consultation service on caregiver burden over time between terminally ill cancer and non-cancer family caregivers

Li-Fen Wu, Chin Lin, Yu-Chun Hung (et al.)

Purpose : The responsibility of taking care of terminal patients is accepted as a role of family members in Taiwan. Only a few studies have focused on the effect of palliative care consultation service (PCCS) on caregiver burden between terminal cancer family caregivers (CFCs) and non-cancer family caregivers (NCFCs). Therefore, the purpose of this study is to address the effect of PCCS on caregiver burden between CFC and NCFC over time. Methods : A prospective longitudinal study was conducted [...]

Menée aux Etats-Unis par enquête auprès de 30 patients atteints d’un cancer colorectal de stade métastatique, cette étude pilote analyse l’intérêt d’un programme de soins palliatifs intégrés pour réduire leurs symptômes et améliorer leur qualité de vie

Embedded palliative care for patients with metastatic colorectal cancer: a mixed-methods pilot study

Kara E. Bischoff, Carly Zapata, Sarah Sedki (et al.)

Purpose : Palliative care is recommended for patients with metastatic cancer, but there has been limited research about embedded palliative care for specific patient populations. We describe the impact of a pilot program that provided routine, early, integrated palliative care to patients with metastatic colorectal cancer. Methods : Mixed methods pre-post intervention cohort study at an academic cancer center. Thirty control then 30 intervention patients with metastatic colorectal cancer were [...]