Menée aux Etats-Unis à partir de données 2017 portant sur 11 247 adolescents, cette étude analyse l'utilisation de cigarettes électroniques, seules ou avec d'autres substances (tabac, alcool, cannabis), en fonction de plusieurs facteurs sociodémographiques

High school students rarely use e-cigarettes alone: A socio-demographic analysis of poly-substance use among adolescents in the USA

Gilbert, Paul A ; Kava, Christine M ; Afifi, Rima

Most adolescents reporting e-cigarette use have also used combustible tobacco; however, the extent to which they use other substances is less clear. This study assessed e-cigarette use with tobacco, alcohol, or cannabis and quantified the risk of poly-substance use among adolescents overall and by socio-demographic characteristics.Using 2017 Youth Behavioral Risk Factor Surveillance System data from adolescents (grades 9-12) with complete substance use information (n=11,244), we examined [...]

A partir d'une revue de la littérature publiée jusqu'en juin 2019 (33 études ; plus de 50 000 cas), cette méta-analyse évalue l'association entre une consommation de noix et le risque de cancer

Nut Consumption and Risk of Cancer: A Meta-analysis of Prospective Studies

Long, Jieyi ; Ji, Zhi ; Yuan, Peihong ; Long, Tingting ; Liu, Ke ; Li, Jiaoyuan ; Cheng, Liming

Background: Epidemiologic studies have investigated the association between nut intake and risk for multiple cancers. However, current findings are inconsistent and no definite conclusion has been drawn from prospective studies. We therefore conducted this meta-analysis to evaluate the relationship between nut consumption and risk of cancer. Methods: Prospective studies reporting associations between nut intake and risk for all types of cancer were identified by searching Web of Science and [...]

A partir d'une revue systématique de la littérature publiée jusqu'en avril 2019 (16 études ; 1,9 million de participants), cette méta-analyse d'études prospectives évalue l'association entre des modes de vie sains (activité physique, alimentation saine, consommation limitée d'alcool, absence de tabagisme, etc.) et le risque de cancer ou la mortalité par cancer

Combined lifestyle factors, incident cancer, and cancer mortality: a systematic review and meta-analysis of prospective cohort studies

Zhang, Yan-Bo ; Pan, Xiong-Fei ; Chen, Junxiang ; Cao, Anlan ; Zhang, Yu-Ge ; Xia, Lu ; Wang, Jing ; Li, Huiqi ; Liu, Gang ; Pan, An

Background : Cancer poses a huge disease burden, which could be reduced by adopting healthy lifestyles mainly composed of healthy diet, body weight, physical activity, limited alcohol consumption, and avoidance of smoking. However, no systematic review has summarised the relations of combined lifestyle factors with cancer morbidity and mortality. Methods : EMBASE and PubMed were searched up to April 2019. Cohort studies investigating the association of combined lifestyle factors with risks of [...]

Menée aux Etats-unis auprès de 96 018 personnes incluses dans l'essai "Prostate, Lung Colorectal and Ovarian Cancer Screening Trial", cette étude analyse l'association entre la capacité antioxydante totale (antioxydants d'origine alimentaire et supplémentation) et le risque de cancer du pancréas (393 cas) et la mortalité associée (353 décès)

Total antioxidant capacity and pancreatic cancer incidence and mortality in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial

Zhong, Guo-Chao ; Pu, Jian-Yuan ; Wu, Yi-Lin ; Yi, Zhu-Jun ; Wan, Lun ; Wang, Kang ; Hao, Fa-Bao ; Zhao, Yong ; Gong, Jian-Ping

Background: Total antioxidant capacity (TAC) reflects an individual's overall antioxidant intake. We sought to clarify whether higher TAC is associated with lower risks of pancreatic cancer incidence and mortality in the US general population. Methods: A total of 96018 American adults were identified from the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. A ferric reducing ability of plasma score was used to reflect an individual's TAC intake from diet and/or supplements. Cox [...]

Menée aux Etats-Unis à partir de données multicentriques portant sur 159 232 femmes ménopausées (durée moyenne de suivi : 18,3 ans), cette étude analyse l'association entre une supplémentation en vitamines B6, B12 et en acide folique et le risque de cancer du poumon (3 836 cas)

Supplemental one-carbon metabolism related B vitamins and lung cancer risk in the Women's Health Initiative

Brasky, Theodore M. ; Ray, Roberta M. ; Navarro, Sandi L. ; Schenk, Jeannette M. ; Newton, Alison M. ; Neuhouser, Marian L.

We and others have reported associations between B vitamins principally involved in one-carbon metabolism and increased lung cancer risk; however results for women have been inconsistent. Here we report on the association of supplemental vitamins B6, folic acid, and B12 intake and lung cancer risk using data from the Women's Health Initiative (WHI) study of postmenopausal women. Between 1993 and 1998, 161,808 women were recruited to participate in the WHI at 40 clinical centers in the US. After [...]

Menée aux Etats-Unis à partir de données d'une enquête réalisée en 2017 et portant sur 430 personnes âgées de 18 à 26 ans, cette étude analyse l'association entre une consommation excessive d'alcool et la vaccination anti-papillomavirus humain chez les jeunes adultes, puis examine la relation entre des comportements à risque de co-infection VIH/HPV, la réalisation du dépistage du VIH et la vaccination anti-HPV

Binge drinking, HIV/HPV co-infection risk, and HIV testing: Factors associated with HPV vaccination among young adults in the United States

Olusanya, O. O. ; Wigfall, L. T. ; Rossheim, M. E. ; Tomar, A. ; Barry, A. E.

Human papillomavirus (HPV) is a common sexually transmitted infection. Binge drinkers often engage in HIV/HPV co-infection high-risk behaviors. We examined the association between binge drinking, HIV/HPV co-infection risk, HIV testing and HPV vaccination among young adults. Data from the 2017 Behavioral Risk Factor Surveillance System survey were examined. Participants (N = 430/450,016; 0.11%) were HPV vaccine-eligible young adults ages 18–26 years. Multivariable logistic regression examined [...]

Menée au Japon, cette étude de modélisation estime l'impact de la crise vaccinale anti-papillomavirus humain de 2013 à 2019 sur l'incidence du cancer du col utérin et la mortalité spécifique

Impact of HPV vaccine hesitancy on cervical cancer in Japan: a modelling study

Simms, Kate T. ; Hanley, Sharon J. B. ; Smith, Megan A. ; Keane, Adam ; Canfell, Karen

Background: Funding for human papillomavirus (HPV) vaccination in Japan began in 2010 for girls aged 12–16 years, with three-dose coverage initially reaching more than 70%. On June 14, 2013, 2 months after formal inclusion in Japan's national immunisation programme, proactive recommendations for the HPV vaccine were suspended following reports of adverse events since found to be unrelated to vaccination, but which were extensively covered in the media. Vaccine coverage subsequently dropped to [...]