A partir d'une revue systématique de la littérature publiée jusqu'en octobre 2018 (29 études ; 1 828 patients), cette méta-analyse évalue les effets du yoga sur l'état de fatigue avant et après une intervention chez des patients atteints d'un cancer

The Impact of Yoga on Fatigue in Cancer Survivorship: A Meta-Analysis

Armer, Jessica S ; Lutgendorf, Susan K

Mind-body approaches, particularly yoga, are used by cancer survivors to cope with treatment-related symptoms. Consistency of yoga-related effects on treatment-related symptoms are not known. This meta-analysis was designed to examine effects of yoga on pre-to-post-intervention improvements in fatigue among cancer patients.PubMed and PsycINFO were searched for peer-reviewed articles of yoga RCTs including cancer survivors and reporting at least one fatigue measure. 29 studies met inclusion [...]

Menée auprès de 400 patients souffrant de douleurs liées au cancer (âge moyen : 58-60 ans), cette étude analyse l'effet d'une intervention impliquant une équipe multidisciplinaire avec des pharmaciens pour améliorer la prise en charge de la douleur

Multidisciplinary intervention incorporating pharmacists in management of opioid-naïve patients with moderate to severe cancer pain

Ding, Haiying ; Zheng, Xiaowei ; Kong, Sisi ; Gong, Liyan ; Ding, Qunfang ; Huang, Ping

Objective : This study aims to investigate the impact of intervention of multidisciplinary team incorporating pharmacists for management of opioid-naïve patients with moderate to severe cancer pain. Methods : A retrospective cohort study was conducted to compare pre- and post-multidisciplinary intervention groups in opioid-naïve patients with moderate to severe cancer pain. Primary outcome was the proportions of appropriate pain assessment and opioid titration. Secondary outcomes were pain [...]

Cet article fait le point sur la prise en charge des crises d'épilepsie chez les patients atteints d'un cancer

Seizures in patients with cancer

Gonzalez Castro, L. Nicolas ; Milligan, Tracey A.

Seizures are common in patients with cancer and either result from brain lesions, paraneoplastic syndromes, and complications of cancer treatment or are provoked by systemic illness (metabolic derangements, infections). Evaluation should include a tailored history, neurologic examination, laboratory studies, neuroimaging, and electroencephalogram. In unprovoked seizures, antiepileptic drug (AED) treatment is required, and a nonenzyme-inducing AED is preferred. Treatment of the underlying cancer [...]

Menée en France sur la période 2009-2012 auprès de 347 patients atteints d'un adénocarcinome de l'intestin grêle (âge médian : 63 ans), cette étude multicentrique analyse la prévalence, la survie et les facteurs prédictifs de la maladie

Small bowel adenocarcinoma: Results from a nationwide prospective ARCAD-NADEGE cohort study of 347 patients

Aparicio, Thomas ; Henriques, Julie ; Manfredi, Sylvain ; Tougeron, David ; Bouche, Olivier ; Pezet, Denis ; Piessen, Guillaume ; Coriat, Romain ; Zaanan, Aziz ; Legoux, Jean-Louis ; Terrebone, Eric ; Pocard, Marc ; Gornet, Jean-Marc ; Lecomte, Thierry ; Lombard-Bohas, Catherine ; Perrier, Hervé ; lecaille, cedric ; Lavau-Denes, Sandrine ; Vernerey, Dewi ; Afchain, Pauline ; NADEGE Investigators

Small bowel adenocarcinoma (SBA) is a rare tumour. We conducted a prospective cohort to describe the prevalence, survival and prognostic factors in unselected SBA patients. The study enrolled patients with all stages of newly diagnosed or recurrent SBA at 74 French centres between January 2009 and December 2012. In total, 347 patients were analysed; the median age was 63 years (range 23–90). The primary tumour was in the duodenum (60.6%), jejunum (20.7%) and ileum (18.7%). The prevalence of [...]

Menée aux Etats-Unis auprès de 37 425 adolescents ou jeunes adultes (âge : 15-39 ans), cette étude compare le risque d'hospitalisation chez des patients ayant survécu à un cancer, chez leurs frères et sœurs et dans la population générale

Hospitalization after Adolescent and Young Adult (AYA) Cancer: A Population-Based Study in Utah

Anderson, Chelsea ; Kaddas, Heydon K. ; Ou, Judy Y. ; Ramsay, Joemy M. ; Trogdon, Justin G. ; Kirchhoff, Anne C. ; Nichols, Hazel B.

Background: Adolescents and young adults (AYA, age 15–39 years) with cancer may be at elevated risk for late morbidity following their cancer treatment, but few studies have quantified the excess burden of severe disease in this population. Using population-based data from Utah, we examined the risk of inpatient hospitalizations among AYA cancer survivors compared with their siblings and the general population. Methods: Survivors of AYA cancer who were ≥2 years from diagnosis and diagnosed from [...]

Menée à partir des données des cohortes "the Nurses’ Health Study" et "the Health Professionals Follow-Up Study" portant sur 82 348 femmes et 40 278 hommes (durée de suivi : 3 354 957 personnes-années), cette étude analyse l'association entre une consommation régulière de yaourts et la mortalité toutes causes confondues et par cancer (nombre de décès : 20 831 femmes, 12 397 hommes)

Yogurt consumption in relation to mortality from cardiovascular disease, cancer, and all causes: a prospective investigation in 2 cohorts of US women and men

Schmid, Daniela ; Song, Mingyang ; Zhang, Xuehong ; Willett, Walter C ; Vaidya, Rita ; Giovannucci, Edward L ; Michels, Karin B

Although a link between regular yogurt consumption and mortality appears plausible, data are sparse and have yielded inconsistent results.We examined the association between regular yogurt consumption and risk of all-cause and cause-specific mortality among US women and men.A total of 82,348 women in the Nurses’ Health Study and 40,278 men in the Health Professionals Follow-Up Study without a history of cardiovascular disease (CVD) and cancer in 1980 (women) or 1986 (men) were followed up until [...]

Cet article met en évidence l'inadéquation entre l'augmentation du nombre de patients atteints de cancer nécessitant des soins et le nombre de professionnels de santé exerçant en oncologie aux Etats-Unis

The Future of Cancer Care in the United States—Overcoming Workforce Capacity Limitations

Shulman, Lawrence N. ; Sheldon, Lisa Kennedy ; Benz, Edward J.

The growth in the number of patients with cancer and cancer survivors in the United States is greatly outpacing the number of clinicians available to care for them. Although age-adjusted cancer incidences and mortality rates are decreasing in the United States, population growth and aging have contributed to a substantial increase in patients requiring cancer care and survivorship care. According to the American Association for Cancer Research, approximately 1.76 million people were expected to [...]

Menée aux Etats-Unis à l'aide de données 2004-2016 des registres des cancers, cette étude analyse, en fonction de l'âge au diagnostic, l'incidence de l'adénocarcinome canalaire pancréatique de stade IA ainsi que la survie

Recent trends in the incidence and survival of Stage 1A Pancreatic Cancer: A Surveillance, Epidemiology, and End Results analysis

Blackford, Amanda L ; Canto, Marcia Irene ; Klein, Alison P ; Hruban, Ralph H ; Goggins, Michael

Rapid access to pancreatic imaging and regular pancreatic surveillance may help identify Stage I pancreatic cancer. We investigated recent trends in the stage of newly-diagnosed PDACs, age at diagnosis, and survival.Trends in age-adjusted incidence of Stage IA pancreatic ductal adenocarcinoma (PDAC) between 2004 and 2016 were determined from the National Cancer Institute’s Surveillance, Epidemiology and End Results (SEER) database. All tests were two-sided.The incidence of Stage IA PDAC cases [...]

Menée en Suisse à partir de données du registre des cancers portant sur 499 patients atteints d'un cancer du poumon non à petites cellules, cette étude compare l'effet de nouveaux traitements sur la survie spécifique en fonction de l'âge (plus ou moins de 70 ans)

Does progress achieved in the treatment of patients with metastatic non-small-cell lung cancer reach the elderly population? A cohort study from a cancer centre from Eastern Switzerland

Schmid, Sabine ; Suipyte, Jorune ; Herrmann, Christian ; Mousavi, Mohsen ; Hitz, Felicitas ; Früh, Martin

Objective : Treatment options for non-small-cell lung cancer (NSCLC) have been evolving. The goal of our study was to evaluate whether novel therapeutics are used in the elderly population and improve outcomes to a similar extent as in young patients. Methods : We enrolled patients registered in the Cancer Registry of Eastern Switzerland and grouped them into four cohorts: Elderly patients aged ≥70 years diagnosed 2005–2007 and 2015–2016 (elderly cohorts 1,2) were compared to cohorts of [...]

Menée aux Etats-Unis auprès de 1 431 femmes ménopausées atteintes d'un cancer colorectal de stade I à IV diagnostiqué entre 1993 et 2017 (âge médian au diagnostic : 72,3 ans), cette étude analyse l'association entre le soutien social perçu, l'intégration sociale, le fait de vivre seul et la mortalité globale ou spécifique

Prediagnosis social support, social integration, living status, and colorectal cancer mortality in postmenopausal women from the women's health initiative

Kroenke, Candyce H. ; Paskett, Electra D. ; Cené, Crystal W. ; Caan, Bette J. ; Luo, Juhua ; Shadyab, Aladdin H. ; Robinson, Jamaica R. M. ; Nassir, Rami ; Lane, Dorothy S. ; Anderson, Garnet L.

Background : We evaluated associations between perceived social support, social integration, living alone, and colorectal cancer (CRC) outcomes in postmenopausal women. Methods : The study included 1431 women from the Women's Health Initiative who were diagnosed from 1993 through 2017 with stage I through IV CRC and who responded to the Medical Outcomes Study Social Support survey before their CRC diagnosis. We used proportional hazards regression to evaluate associations of social support [...]

Menée à l'aide de données de l'Organisation Mondiale de la Santé, cette étude analyse l'incidence des cancers buccaux et pharyngés et la mortalité associée, par sous-sites anatomiques et en fonction du sexe

Global Trends in Oral and Pharyngeal Cancer Incidence and Mortality

Bosetti, Cristina ; Carioli, Greta ; Santucci, Claudia ; Bertuccio, Paola ; GALLUS, Silvano ; Garavello, Werner ; Negri, Eva ; La Vecchia, Carlo

To provide an up-to-date overview of recent trends in mortality from oral and pharyngeal cancer, we analysed death certification data for 61 countries worldwide provided by the World Health Organization in 2010-2015, and, for selected most populous countries, over the period 1970-2016. For 12 largest countries, we analysed incidence derived from Cancer Incidence in Five Continents in 1960-2012 for all oral and pharyngeal cancers and by subsites. In 2015, male age-standardized (world population) [...]