Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
Pour retrouver les publications signalées par Nota Bene Cancer (archives indexées à partir du n°127 du 1" mars 2012) :
Sommaire du n° 565 du 16 mai 2023
Qualité de vie, soins de support (4)
A partir d'une revue systématique de la littérature publiée entre 2000 et 2022 (28 articles), cette étude présente des recommandations en matière de soins de réadaptation pour les enfants atteints d'un cancer
Clinical practice guideline and expert consensus recommendations for rehabilitation among children with cancer: A systematic review
A partir d'une revue systématique de la littérature publiée entre 2000 et 2022 (28 articles), cette étude présente des recommandations en matière de soins de réadaptation pour les enfants atteints d'un cancer
Clinical practice guideline and expert consensus recommendations for rehabilitation among children with cancer: A systematic review
L’Hotta, Allison J. ; Randolph, Samantha B. ; Reader, Ben ; Lipsey, Kim ; King, Allison A.
Increased attention to the rehabilitation needs of children with cancer is vital to enhance health, quality-of-life, and productivity outcomes. Among adults with cancer, rehabilitation recommendations are frequently incorporated into guidelines, but the extent to which recommendations exist for children is unknown. Reports included in this systematic review are guideline or expert consensus reports containing recommendations related to rehabilitation referral, evaluation, and/or intervention [...]
Cette étude passe en revue les traitements d'une thromboembolie veineuse chez les patients atteints d'un cancer
Treatment of Cancer-Associated Thrombosis: Recent Advances, Unmet Needs, and Future Direction
Cette étude passe en revue les traitements d'une thromboembolie veineuse chez les patients atteints d'un cancer
Treatment of Cancer-Associated Thrombosis: Recent Advances, Unmet Needs, and Future Direction
Wang, Tzu-Fei ; Khorana, Alok A ; Agnelli, Giancarlo ; Bloomfield, Dan ; Bonaca, Marc P ; Büller, Harry R ; Connors, Jean M ; Goto, Shinya ; Jing, Zhi-Cheng ; Kakkar, Ajay K ; Khder, Yasser ; Raskob, Gary E ; Soff, Gerald A ; Verhamme, Peter ; Weitz, Jeffrey I ; Carrier, Marc
Cancer-associated thrombosis, with the incidence rising over the years, is associated with significant morbidity and mortality in patients with cancer. Recent advances in the treatment of cancer-associated venous thromboembolism (VTE) include the introduction of direct oral anticoagulants (DOACs), which provide a more convenient and effective option than low-molecular-weight heparin (LMWH). Nonetheless, important unmet needs remain including an increased risk of bleeding in certain patient [...]
Menée aux Etats-Unis par enquête auprès de 324 adolescents et jeunes adultes atteints d'un cancer, cette étude analyse l'association entre leurs besoins en soins et leur état de santé auto-déclaré
The relationship between unmet cancer care needs and self-rated health among adolescents and young adults with cancer
Menée aux Etats-Unis par enquête auprès de 324 adolescents et jeunes adultes atteints d'un cancer, cette étude analyse l'association entre leurs besoins en soins et leur état de santé auto-déclaré
The relationship between unmet cancer care needs and self-rated health among adolescents and young adults with cancer
Zhang, Anao ; Delly, Joseph ; Meister, Dalton ; Jackson Levin, Nina ; Blumenstein, Kate ; Stuchell, Beth ; Walling, Emily
Background: Adolescents and young adults (AYA) with cancer face unique psychosocial challenges that often impact their outcomes, including self-rated health. To date, few studies have focused on AYA cancer survivors’ multidimensional unmet needs of cancer care in relation to their health status. Methods/Procedure: This study surveyed 324 AYA cancer survivors in a cross-sectional design using the Cancer Needs Questionnaire – Young People (CNQ-YP). In addition to descriptive statistics and [...]
A partir d'une revue systématique de la littérature (12 études), cette étude analyse l'intérêt des interventions à base d'exercices physiques chez des patients atteints d'un cancer hématologique traité par chimiothérapie
Safety and feasibility of exercise interventions in patients with hematological cancer undergoing chemotherapy: a systematic review
A partir d'une revue systématique de la littérature (12 études), cette étude analyse l'intérêt des interventions à base d'exercices physiques chez des patients atteints d'un cancer hématologique traité par chimiothérapie
Safety and feasibility of exercise interventions in patients with hematological cancer undergoing chemotherapy: a systematic review
Großek, Anja ; Großek, Karla ; Bloch, Wilhelm
Objective: Exercise during and after cancer treatment has established quality of life and health benefits. However, particularly for patients with hematological cancer clear recommendations regarding the safety and feasibility of exercise are under-investigated. The aim of our systematic review was to summarize the literature regarding the feasibility and safety of exercise interventions in patients diagnosed with hematological cancer undergoing chemotherapy. Method: A systematic literature [...]
Observation (7)
Menée à partir des données 1988-2017 du registre californien des cancers portant sur 51 533 patients atteints d'un carcinome hépatocellulaire, cette étude analyse l'association entre le lieu de naissance, l'origine ethnique et la survie
Association of Nativity with Survival among Adults with Hepatocellular Carcinoma
Menée à partir des données 1988-2017 du registre californien des cancers portant sur 51 533 patients atteints d'un carcinome hépatocellulaire, cette étude analyse l'association entre le lieu de naissance, l'origine ethnique et la survie
Association of Nativity with Survival among Adults with Hepatocellular Carcinoma
Zhou, Kali ; Song, Ziwei ; Rostomian, Nairi ; Dodge, Jennifer L ; Stern, Mariana C ; Setiawan, V Wendy ; Terrault, Norah A ; Cockburn, Myles G ; Liu, Lihua
Immigrants comprise a significant proportion of those diagnosed with hepatocellular carcinoma (HCC) in the United States (US). Nativity or birthplace impacts incidence and risk factors for HCC, but little is known about its influence on survival after diagnosis.We identified 51,533 adults with HCC with available birthplace in the California Cancer Registry between 1988 and 2017. Cases were categorized as foreign-born or US-born and stratified by mutually exclusive race and ethnicity groups. [...]
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Learning from Adaptations to the COVID-19 Pandemic: How Teleconsultation Supported Cancer Care Pathways at a Comprehensive Cancer Center in Norther...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Learning from Adaptations to the COVID-19 Pandemic: How Teleconsultation Supported Cancer Care Pathways at a Comprehensive Cancer Center in Northern Italy
Caviola, Giada ; Daolio, Jessica ; Pellegri, Carlotta ; Cigarini, Francesca ; Braglia, Luca ; Foracchia, Marco ; Mazzini, Elisa ; Cerullo, Loredana
Multidisciplinary team (MDT) meetings are recognized as the gold standard for care management of cancer patients, and during the COVID-19 pandemic they were considered a priority to be maintained. Due to pandemic-related restrictions, MDT meetings were forcibly converted from in-person to telematic format. This retrospective study evaluated the annual performance of four MDT meeting indicators (MDT members’ attendance, number of discussed cases, frequency of MDT meetings, and duration) between [...]
Deciphering the Relationship between SARS-CoV-2 and Cancer
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Deciphering the Relationship between SARS-CoV-2 and Cancer
Costanzo, Michele ; De Giglio, Maria Anna Rachele ; Roviello, Giovanni Nicola
Some viruses are known to be associated with the onset of specific cancers. These microorganisms, oncogenic viruses or oncoviruses, can convert normal cells into cancer cells by modulating the central metabolic pathways or hampering genomic integrity mechanisms, consequently inhibiting the apoptotic machinery and/or enhancing cell proliferation. Seven oncogenic viruses are known to promote tumorigenesis in humans: human papillomavirus (HPV), hepatitis B and C viruses (HBV, HCV), Epstein-Barr [...]
The impact of the Covid-19 pandemic on the stage of endometrial cancer at diagnosis
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
The impact of the Covid-19 pandemic on the stage of endometrial cancer at diagnosis
Garrett, Audrey P. ; Seidman, Benjamin C.
Background : Endometrial cancer generally presents at an early stage affording a high rate of surgical cure. Early in the Covid-19 pandemic it was suggested that treatment of tumors with favorable pathologic features might safely be delayed. Objective: We hypothesized that disruption to health care services during the pandemic would impact the stage at presentation for these patients. Here we compare the stage at presentation of Endometrial Cancer in the months immediately preceding the [...]
COVID-19 and Other Viral Infections in Patients With Hematologic Malignancies
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
COVID-19 and Other Viral Infections in Patients With Hematologic Malignancies
Courtney E. Harris ; Abi Vijenthira ; Shin Yeu Ong ; Lindsey Robert Baden ; Lisa K. Hicks ; John H. Baird
COVID-19 and our armamentarium of strategies to combat it have evolved dramatically since the virus first emerged in late 2019. Vaccination remains the primary strategy to prevent severe illness, although the protective effect can vary in patients with hematologic malignancy. Strategies such as additional vaccine doses and now bivalent boosters can contribute to increased immune response, especially in the face of evolving viral variants. Because of these new variants, no approved monoclonal [...]
Clinical Features and Risk Factors Associated With Multisystem Inflammatory Syndrome in Children With Cancer and COVID-19
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Clinical Features and Risk Factors Associated With Multisystem Inflammatory Syndrome in Children With Cancer and COVID-19
Martin, Samantha D. ; Davis, Elizabeth S. ; Dai, Chen ; Boal, Lauren H. ; Araya, Brook ; Brackett, Julienne ; Dickens, David ; Kahn, Alissa ; Martinez, Isaac ; Sharma, Archana ; Schwalm, Carla ; Aguayo-Hiraldo, Paibel ; Bhatia, Smita ; Levine, Jennifer M. ; Johnston, Emily E. ; Wolfson, Julie A. ; Pediatric Oncology COVID-19 Case Consortium
Little is known about the risk of post–COVID-19 multisystem inflammatory syndrome in children (MIS-C) in the setting of childhood cancer.To evaluate factors associated with MIS-C and describe the clinical course of COVID-19 in the setting of MIS-C.Multisite observational cohort study of a registry representing more than 100 US pediatric oncology sites. All included patients were registered between April 1, 2020, and May 18, 2022. Sites submitted deidentified data surrounding sociodemographics, [...]
Diagnosis and treatment of lung cancer in Denmark during the COVID-19 pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Diagnosis and treatment of lung cancer in Denmark during the COVID-19 pandemic
Olesen, Tina Bech ; Rasmussen, Torben Riis ; Jakobsen, Erik ; Engberg, Henriette ; Hilberg, Ole ; Møller, Henrik ; Jensen, Jens Winther ; Jensen, Henry
Background : We examined the number of lung cancers diagnosed, the quality of care and the socio-economic and clinical characteristics among patients with lung cancer during the COVID-19 pandemic compared to previous years. Methods : We included all patients ≥ 18 years old diagnosed with lung cancer from 01 January 2018 to 31 August 2021 as registered in the Danish Lung Cancer Registry. Using a generalised linear model, we estimated prevalence ratios (PR) and 95% confidence intervals (CI) of [...]
Immune Response following BNT162b2 mRNA COVID-19 Vaccination in Pediatric Cancer Patients
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Immune Response following BNT162b2 mRNA COVID-19 Vaccination in Pediatric Cancer Patients
Schmidt, K. L. Juliëtte ; Dautzenberg, Noël M. M. ; Hoogerbrugge, Peter M. ; Lindemans, Caroline A. ; Nierkens, Stefan ; Smits, Gaby ; van Binnendijk, Rob S. ; Bont, Louis J. ; Tissing, Wim J. E.
COVID-19 vaccinations are recommended for children with cancer but data on their vaccination response is scarce. This study assesses the antibody and T-cell response following a 2- or 3-dose vaccination with BNT162b2 mRNA COVID-19 vaccine in children (5–17 years) with cancer. For the antibody response, participants with a serum concentration of anti-SARS-CoV-2 spike 1 antibodies of >300 binding antibody units per milliliter were classified as good responders. For the T-cell response, [...]
Comparing telemedicine and in-person gastrointestinal cancer genetic appointment outcomes during the COVID-19 pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Comparing telemedicine and in-person gastrointestinal cancer genetic appointment outcomes during the COVID-19 pandemic
Williams, Samantha ; Ebrahimzadeh, Jessica E. ; Clay, Daniel ; Constantino, Gillian ; Heiman, Jordan ; Wangensteen, Kirk J. ; Valverde, Kathleen ; Mahmud, Nadim ; Katona, Bryson W.
Background: The study purpose is to compare outcomes associated with completion of genetic testing between telemedicine and in-person gastrointestinal cancer risk assessment appointments during the COVID-19 pandemic. Methods: Data was collected on patients with scheduled appointments between July 2020 and June 2021 in a gastrointestinal cancer risk evaluation program (GI-CREP) that utilized both telemedicine and in-person visits throughout the COVID-19 pandemic, and a survey was administered. [...]
Menée aux Etats-Unis à partir de données portant sur 25 656 patients ayant survécu à un cancer pédiatrique diagnostiqué entre 1970 et 1999 (âge médian au diagnostic : 6,1 ans ; durée médiane de suivi : 21,8 ans), cette étude de cohorte analyse l'association entre les traitements anticancéreux reçus pendant l'enfance et le nombre d'interventions chirurgicales ultérieures nécessitant une anesthésie
Cumulative burden of late, major surgical intervention in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study (CCSS) c...
Menée aux Etats-Unis à partir de données portant sur 25 656 patients ayant survécu à un cancer pédiatrique diagnostiqué entre 1970 et 1999 (âge médian au diagnostic : 6,1 ans ; durée médiane de suivi : 21,8 ans), cette étude de cohorte analyse l'association entre les traitements anticancéreux reçus pendant l'enfance et le nombre d'interventions chirurgicales ultérieures nécessitant une anesthésie
Cumulative burden of late, major surgical intervention in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study (CCSS) cohort
Dieffenbach, Bryan V. ; Murphy, Andrew J. ; Liu, Qi ; Ramsey, Duncan C. ; Geiger, Erik J. ; Diller, Lisa R. ; Howell, Rebecca M. ; Oeffinger, Kevin C. ; Robison, Leslie L. ; Yasui, Yutaka ; Armstrong, Gregory T. ; Chow, Eric J. ; Weil, Brent R. ; Weldon, Christopher B.
Background: Multimodal cancer therapy places childhood cancer survivors at increased risk for chronic health conditions, subsequent malignancies, and premature mortality as they age. We aimed to estimate the cumulative burden of late (>5 years from cancer diagnosis), major surgical interventions among childhood cancer survivors, compared with their siblings, and to examine associations between specific childhood cancer treatments and the burden of late surgical interventions. Methods: We [...]
Long-term surgical consequences of childhood cancer
Menée aux Etats-Unis à partir de données portant sur 25 656 patients ayant survécu à un cancer pédiatrique diagnostiqué entre 1970 et 1999 (âge médian au diagnostic : 6,1 ans ; durée médiane de suivi : 21,8 ans), cette étude de cohorte analyse l'association entre les traitements anticancéreux reçus pendant l'enfance et le nombre d'interventions chirurgicales ultérieures nécessitant une anesthésie
Long-term surgical consequences of childhood cancer
Youlden, Danny R. ; Pole, Jason D. ; Baxter, Nancy N. ; Aitken, Joanne F.
Late effects are a potentially life-changing complication of childhood cancer and its treatment. Cytotoxic chemotherapy and radiotherapy at a young age can seriously damage developing organs and body systems. Patients who survive childhood cancer must live with the long-term consequences of this unintended harm into adulthood and beyond.
Menée aux Etats-Unis par enquête auprès de 4 130 patients ayant survécu à un cancer, cette étude analyse leurs difficultés médicales et financières ainsi que l'insécurité alimentaire associée
Medical Financial Hardship and Food Security among Cancer Survivors in the United States
Menée aux Etats-Unis par enquête auprès de 4 130 patients ayant survécu à un cancer, cette étude analyse leurs difficultés médicales et financières ainsi que l'insécurité alimentaire associée
Medical Financial Hardship and Food Security among Cancer Survivors in the United States
Hallgren, Emily ; Narcisse, Marie-Rachelle ; Andersen, Jennifer A. ; Willis, Don E. ; Thompson, Tess ; Bryant-Smith, Gwendolyn ; McElfish, Pearl A.
Background: Some cancer survivors experience medical financial hardship, which may reduce their food security. The purpose of this study was to explore whether medical financial hardship is related to food security among cancer survivors. Methods: The study was based on cross-sectional data from the 2020 National Health Interview Survey. We used ordinal logistic regression to examine the relationship between material, psychological, and behavioral medical financial hardship and household food [...]
Menée en Allemagne à partir de données 1991-2016, cette étude analyse l'évolution de la survie globale chez des enfants atteints d'un cancer (âge : 0-14 ans)
Temporal patterns of childhood cancer survival 1991 to 2016: A nationwide register-study based on data from the German Childhood Cancer Registry
Menée en Allemagne à partir de données 1991-2016, cette étude analyse l'évolution de la survie globale chez des enfants atteints d'un cancer (âge : 0-14 ans)
Temporal patterns of childhood cancer survival 1991 to 2016: A nationwide register-study based on data from the German Childhood Cancer Registry
Wellbrock, Maike ; Spix, Claudia ; Ronckers, Cecile M. ; Grabow, Desiree ; Filbert, Anna-Liesa ; Borkhardt, Arndt ; Wollschläger, Daniel ; Erdmann, Friederike
Childhood cancer is the leading disease-related cause of death among under 15?year olds in Europe. Since primary preventive measures are lacking, improving survival probabilities and long-term well-being remain primary goals. With this report, we provide the first long-term assessment and interpretation of patterns in childhood cancer survival in Germany, covering a period of 30?years. Using data from the German Childhood Cancer Registry, we assessed temporal patterns of cancer survival among [...]
Menée à partir de données portant sur 1 175 patients atteints d'un cancer du côlon de stade III, cette étude prospective analyse l'association entre la durée du sommeil auto-déclarée, la survie sans maladie et la survie globale
Sleep and cancer recurrence and survival in patients with resected Stage III colon cancer: findings from CALGB/SWOG 80702 (Alliance)
Menée à partir de données portant sur 1 175 patients atteints d'un cancer du côlon de stade III, cette étude prospective analyse l'association entre la durée du sommeil auto-déclarée, la survie sans maladie et la survie globale
Sleep and cancer recurrence and survival in patients with resected Stage III colon cancer: findings from CALGB/SWOG 80702 (Alliance)
Lee, Seohyuk ; Ma, Chao ; Shi, Qian ; Meyers, Jeffrey ; Kumar, Pankaj ; Couture, Felix ; Kuebler, Philip ; Krishnamurthi, Smitha ; Lewis, DeQuincy ; Tan, Benjamin ; O’Reilly, Eileen M. ; Shields, Anthony F. ; Meyerhardt, Jeffrey A.
Background: We sought to assess the influences of sleep duration, sleep adequacy, and daytime sleepiness on survival outcomes among Stage III colon cancer patients. Methods: We conducted a prospective observational study of 1175 Stage III colon cancer patients enrolled in the CALGB/SWOG 80702 randomised adjuvant chemotherapy trial who completed a self-reported questionnaire on dietary and lifestyle habits 14–16 months post-randomisation. The primary endpoint was disease-free survival (DFS), and [...]
Menée en Europe, en Australie et aux Etats-Unis à partir de données portant sur 280 patients ayant survécu au moins 5 ans à un glioblastome (âge médian : 56 ans), cette étude analyse la survie globale en fonction de la présence d'une mutation au niveau du gène de l'isocitrate déshydrogénase
Long-term survival with IDH wildtype glioblastoma: first results from the ETERNITY Brain Tumor Funders' Collaborative Consortium (EORTC 1419)
Menée en Europe, en Australie et aux Etats-Unis à partir de données portant sur 280 patients ayant survécu au moins 5 ans à un glioblastome (âge médian : 56 ans), cette étude analyse la survie globale en fonction de la présence d'une mutation au niveau du gène de l'isocitrate déshydrogénase
Long-term survival with IDH wildtype glioblastoma: first results from the ETERNITY Brain Tumor Funders' Collaborative Consortium (EORTC 1419)
Hertler, Caroline ; Felsberg, Jörg ; Gramatzki, Dorothee ; Le Rhun, Emilie ; Clarke, Jennifer ; Soffietti, Riccardo ; Wick, Wolfgang ; Chinot, Olivier ; Ducray, François ; Roth, Patrick ; McDonald, Kerrie ; Hau, Peter ; Hottinger, Andreas F. ; Reijneveld, Jaap ; Schnell, Oliver ; Marosi, Christine ; Glantz, Michael ; Darlix, Amélie ; Lombardi, Giuseppe ; Krex, Dietmar ; Glas, Martin ; Reardon, David A. ; van den Bent, Martin ; Lefranc, Florence ; Herrlinger, Ulrich ; Razis, Evangelia ; Carpentier, Antoine F. ; Phillips, Samuel ; Rudà, Roberta ; Wick, Antje ; Tabouret, Emeline ; Meyronet, David ; Maurage, Claude-Alain ; Rushing, Elisabeth ; Rapkins, Robert ; Bumes, Elisabeth ; Hegi, Monika ; Weyerbrock, Astrid ; Aregawi, Dawit ; Gonzalez-Gomez, Christian ; Pellerino, Alessia ; Klein, Martin ; Preusser, Matthias ; Bendszus, Martin ; Golfinopoulos, Vassilis ; von Deimling, Andreas ; Gorlia, Thierry ; Wen, Patrick Y. ; Reifenberger, Guido ; Weller, Michael
Background: Median survival with glioblastoma remains in the range of 12 months on population levels. Only few patients survive for more than 5 years. Patient and disease features associated with long-term survival remain poorly defined. Methods: European Organization for Research and Treatment of Cancer (EORTC) 1419 (ETERNITY) is a registry study supported by the Brain Tumor Funders Collaborative in the US and the EORTC Brain Tumor Group. Patients with glioblastoma surviving at least 5 years [...]
Approches psycho-sociales (1)
Menée aux Pays-Bas à partir de données portant sur 1 713 patients ayant survécu à un cancer pédiatrique, cette étude identifie les facteurs socio-démographiques et médicaux associés aux conséquences positives ou négatives de la maladie sur leur santé psychique
Positive and negative survivor-specific psychosocial consequences of childhood cancer: the DCCSS-LATER 2 psycho-oncology study
Menée aux Pays-Bas à partir de données portant sur 1 713 patients ayant survécu à un cancer pédiatrique, cette étude identifie les facteurs socio-démographiques et médicaux associés aux conséquences positives ou négatives de la maladie sur leur santé psychique
Positive and negative survivor-specific psychosocial consequences of childhood cancer: the DCCSS-LATER 2 psycho-oncology study
Maas, Anne ; Maurice-Stam, Heleen ; van der Aa-van Delden, Alied M. ; van Dalen, Elvira C. ; van Dulmen-den Broeder, Eline ; Tissing, Wim J. E. ; Loonen, Jacqueline J. ; van der Pal, Helena J. H. ; de Vries, Andrica C. H. ; van den Heuvel-Eibrink, Marry M. ; Janssens, Geert O. ; Ronckers, Cecile ; Neggers, Sebastian ; Bresters, Dorine ; Louwerens, Marloes ; Versluys, Birgitta A. B. ; van der Heiden-van der Loo, Margriet ; Kremer, Leontien C. M. ; van Gorp, Marloes ; Grootenhuis, Martha A. ; on behalf of the Dutch, Later study group
Purpose: Numerous studies investigated generic psychosocial outcomes in survivors of childhood cancer (CCS). The present study aimed to describe survivor-specific psychosocial consequences in CCS, and to identify socio-demographic and medical associated factors. Methods: CCS from the Dutch Childhood Cancer Survivor Study (DCCSS)-LATER cohort (diagnosed 1963–2001) part 2 (age ≥ 18 years, diagnosed < 18 years, ≥ 5 years since diagnosis) completed the Benefit & Burden Scale (BBSC) and the Impact [...]