Excess Weight and Risk of Second Cancers Among Cancer Survivors—Sounding the Alarm on Future Trends

Menée à l'aide de données d'enquêtes américaines réalisées auprès de 6 894 personnes ayant survécu à un premier cancer non métastatique diagnostiqué sur la période 1992-2015 (âge moyen au premier diagnostic : 72,2 ans ; 59,2 % d'hommes), cette étude analyse le risque de second cancer primitif lié au surpoids

Résumé en anglais

In a recent study, Bodelon et al identified 26 894 participants who received a diagnosis of a first primary nonmetastatic cancer during follow-up of the Cancer Prevention Study-II cohort. They found that those with overweight (body mass index [BMI; calculated as weight in kilograms divided by height in meters squared] of 25.0-29.9) or obesity (BMI ≥30.0) around the time of the first primary cancer diagnosis had a 15% and 34% greater risk, respectively, of a second primary malignant neoplasm compared with those with normal weight (BMI, 18.5-24.9). These risks were slightly greater after restricting to obesity-related second primary malignant neoplasms. There were associations for several specific obesity-related second cancer types, including colorectal and kidney.